Alessandro Paoletti Perini

ORCID: 0000-0003-2802-4058
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About
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Research Areas
  • Cardiac Arrhythmias and Treatments
  • Cardiac pacing and defibrillation studies
  • Cardiac electrophysiology and arrhythmias
  • Atrial Fibrillation Management and Outcomes
  • Dental Radiography and Imaging
  • Orthodontics and Dentofacial Orthopedics
  • Periodontal Regeneration and Treatments
  • Cardiovascular Function and Risk Factors
  • Dental Implant Techniques and Outcomes
  • Oral and Maxillofacial Pathology
  • Temporomandibular Joint Disorders
  • Cancer Diagnosis and Treatment
  • dental development and anomalies
  • Hemodynamic Monitoring and Therapy
  • Oral and gingival health research
  • Heart Failure Treatment and Management
  • Neurological Disorders and Treatments
  • ECG Monitoring and Analysis
  • Oral microbiology and periodontitis research
  • Cardiomyopathy and Myosin Studies
  • Adhesion, Friction, and Surface Interactions
  • Cardiac Imaging and Diagnostics
  • Endodontics and Root Canal Treatments
  • Healthcare Systems and Public Health
  • Dental Anxiety and Anesthesia Techniques

Santa Maria Nuova Hospital
2018-2025

Azienda Usl Toscana Centro
2019-2025

Veneto Nanotech (Italy)
2024-2025

Azienda Sanitaria di Firenze
2022-2024

Ospedale Santa Maria
2023-2024

Fatebenefratelli Hospital
2023

Azienda Ospedaliera San Gerardo
2023

Istituti di Ricovero e Cura a Carattere Scientifico
2023

Azienda Ospedaliero-Universitaria Careggi
2007-2023

University of Padua
1976-2022

Animal studies showed that papillary muscles can be sources of ventricular fibrillation (VF) in both the left and right ventricle, but this occurrence humans has been described only patients with ischemic heart disease.To investigate role muscle premature contractions (PVCs) as triggers for VF safety feasibility catheter ablation these patients.Six (2 male; age, 40 ± 11 years; 5 a normal structural 1 nonischemic cardiomyopathy) history resulting repetitive implantable cardioverter...

10.1111/jce.12478 article EN Journal of Cardiovascular Electrophysiology 2014-06-20

BackgroundThere are limited real-world data about the extended prognosis of patients with drug-induced type 1 Brugada electrocardiogram (ECG).ObjectiveWe assessed clinical outcomes and predictors life-threatening arrhythmias in ECG.Materials MethodsThis multicenter retrospective study, conducted at 21 Italian Swiss hospitals from July 1997 to May 2021, included consecutive ECG. The primary outcome, a composite appropriate ICD therapies sudden cardiac death (SCD), was along these...

10.1016/j.hrthm.2024.01.015 article EN cc-by-nc-nd Heart Rhythm 2024-01-21

AimsCHADS2 and CHA2DS2-VASc scores are pivotal in assessing the risk of stroke atrial fibrillation patients, were recently proved to predict hospitalizations mortality specific clinical settings. Aim this study was evaluate whether these could outcomes [first hospitalization for heart failure (HF) a combined event HF death any cause] patients candidates cardiac resynchronization therapy implantable defibrillator (CRT-D).

10.1093/europace/eut190 article EN EP Europace 2013-07-04

Hybrid versus Endocardial Ablation for LSPAF Introduction of longstanding persistent atrial fibrillation (LSPAF) is the most challenging procedure in treatment AF, either by surgical or percutaneous approach. Objective We investigated difference success and complication rates between combined epicardial endocardial catheter ablation our standard procedure. Methods Results Twenty‐four consecutive patients (group 1) with enlarged left atrium (>4.5 cm) underwent a procedure, consisting...

10.1111/jce.12926 article EN Journal of Cardiovascular Electrophysiology 2016-01-14

Three different methods, morphologic, immunocytochemic, and fluorescence activated cell sorter (FC) analysis, were compared with respect to their efficiency in detecting breast cancer cells bone marrow. In the first series of experiments, three techniques using marrow artificially mixed a known amount cells, whereas second from patients metastases used. The following results obtained: When mixtures analyzed, FC analysis detected 1% 10% (0.2% was border line value), morphologic method 0.05%...

10.1002/1097-0142(19910215)67:4<1033::aid-cncr2820670428>3.0.co;2-h article EN Cancer 1991-02-15

Summary Following favourable results from a previous study, large, multicentre, prospective, case-control study was performed to further assess the incidence of bleeding complications after dental extraction in patients taking oral anticoagulant therapy (OAT). Four hundred fifty-one being treated with warfarin who required were compared control group 449 non-anticoagulated subjects undergoing same procedure. In warfarin-treated group, regimen maintained unchanged, such that had an...

10.1160/th10-02-0139 article EN Thrombosis and Haemostasis 2010-01-01

Aim: Gender related differences in epidemiology, treatment, and prognosis of heart failure (HF) have been reported. We examined the sex influence patients treated with cardiac resynchronization therapy (CRT). Methods Results: Out 334 consecutive HF (19.7% women) who underwent CRT, 195 reached clinical echocardiographic evaluation at six 12 months were selected for analysis. A reduction left ventricular (LV) end‐diastolic volume/m 2 (EDVi) end systolic (ESVi) was evident overall population (P...

10.1111/j.1540-8159.2007.00870.x article EN Pacing and Clinical Electrophysiology 2007-10-29

Abstract Objective To investigate the influence of presence or absence keratinized mucosa on alveolar bony crest level as it relates to different buccal marginal bone thicknesses. Material and methods In six beagle dogs, mandibular premolars first molars were extracted bilaterally. right side mandible (test), flaps elevated, well part lingual masticatory was removed. The flap released coronally allow a primary wound closure. left side, wounds unsutured with remaining (control). After 3...

10.1111/clr.12233 article EN Clinical Oral Implants Research 2013-07-29

In candidates for cardiac resynchronization therapy (CRT), the choice between pacemaker (CRT-P) and defibrillator (CRT-D) implantation is still debated. We compared long-term prognosis of patients who received CRT-D or CRT-P according to class IA recommendations European Society Cardiology (ESC) were enrolled in a multicentre prospective registry. A total 620 heart failure underwent successful CRT device Contak Italian Registry. This analysis included 266 108 ESC indications. Their survival...

10.1093/europace/eut032 article EN EP Europace 2013-02-24

Abstract Background Few studies have analyzed the clinical and echocardiographic differences between light‐chain ( AL ) transthyretin TTR amyloidosis. Hypothesis The aim of present research was to compare, in a real‐world setting, profiles these kinds amyloidosis, at time diagnosis, using new‐generation echocardiography. Methods Seventy‐nine patients with 48 amyloidosis were studied. Results According criterion mean left ventricular LV thickness &gt;12 mm, 45 (C‐ all had cardiac amyloidotic...

10.1002/clc.22353 article EN Clinical Cardiology 2015-02-01

Premature ventricular complexes (PVCs) and tachycardia (VT) arising from papillary muscles of both ventricles have recently been described. There is a lack data on VT originating the right (RV PAP) muscles. no prior studies focused electrocardiogram (ECG) features ablation PVC/VT septal muscle ventricle.Among 155 consecutive patients with normal structural heart who underwent catheter PVC/VT, 8 RV PAP were identified. The site origin arrhythmias was identified through activation/pace mapping...

10.1111/jce.12551 article EN Journal of Cardiovascular Electrophysiology 2014-09-17

The awareness of radiation doses and risks, also during interventional cardiology procedures, is essential today in order to apply the risk-benefit assessment reinforce principles justification optimisation clinical practice.A voluntary survey with 10 questions multiple-choice answers was run on a popular website (www.cardiolink.it) independently by scientific publisher, evaluate contemporary level multi-speciality sample physicians Italy.One thousand eight hundred sixty-one completed test....

10.1080/00015385.2020.1733303 article EN Acta Cardiologica 2020-03-31

Abstract Background Very high‐power short‐duration (vHPSD) catheters are associated with less irrigation fluid load than standard (STD RF) ablation catheters. However, the impact of this reduction on biomarkers in pulmonary vein isolation (PVI) for atrial fibrillation (AF) remains unknown. Methods and Aim Biomarkers heart failure, myocardial injury, systemic inflammation status as Brain Natriuretic Peptide (BNP), high‐sensitivity Troponin I (hsTnI), C‐reactive protein (CRP) were collected...

10.1002/joa3.70060 article EN cc-by Journal of Arrhythmia 2025-04-01

In this study, we investigate the current accuracy of widely used microplastic (MP) detection methods through an interlaboratory comparison (ILC) involving ISO-approved techniques. The ILC was organized under prestandardization platform VAMAS (Versailles Project on Advanced Materials and Standards) gathered a large number (84) analytical laboratories across globe. aim (i) to test compare two thermo-analytical three spectroscopical with respect their suitability identify quantify...

10.1021/acs.analchem.4c05403 article EN cc-by Analytical Chemistry 2025-04-17

Abstract Background Very–high–power–short duration (vHPSD) catheters are associated with less irrigation fluid load than standard (STD RF) ablation catheters. However, the impact of this reduction on biomarkers in pulmonary vein isolation (PVI) for atrial fibrillation (AF) remains unknown. Methods and aim Biomarkers heart failure, myocardial injury, systemic inflammation status as Brain Natriuretic Peptide (BNP), high sensitivity Troponin I (hsTnI), C–reactive protein (CRP) were collected...

10.1093/eurheartjsupp/suaf076.104 article EN European Heart Journal Supplements 2025-05-01

Abstract Introduction Atrial fibrillation (AF) is one of the most common arrhythmias and its diagnosis often challenging yet crucial for therapeutic, prognostic, quality–of–life considerations. Event recorders may offer an efficient solution diagnosing AF or other in patients with paroxysmal palpitations. We tested a 6–lead event recorder (Kardia6L) symptomatic presenting Materials Methods This prospective study was conducted at Santa Maria Nuova Hospital (Florence, Italy). Thirty–seven were...

10.1093/eurheartjsupp/suaf076.135 article EN European Heart Journal Supplements 2025-05-01

Purpose: Although biomarkers of myocardial fibrosis and inflammation have been proposed as potential modulators response to cardiac resynchronization therapy (CRT), their clinical utility interaction with echocardiographic parameters remain incompletely understood. This study aims assess the dynamic changes in these biomarkers, relationship variables, association structural CRT. Methods: We retrospectively evaluated 86 consecutive patients referred for CRT symptomatic heart failure, left...

10.3390/jcm14103496 article EN Journal of Clinical Medicine 2025-05-16

Introduction: Although optimization of atrioventricular and interventricular delays has been demonstrated to improve hemodynamics in patients with cardiac resynchronization therapy (CRT), the required time‐consuming procedure discourages its use clinical practice. Recently, a new method for CRT based on intracardiac electrogram (IEGM) detected by implanted leads, developed. We evaluated effectiveness this improving left ventricular (LV) asynchrony performance using real‐time 3D...

10.1111/j.1540-8159.2007.00925.x article EN Pacing and Clinical Electrophysiology 2007-12-20

Early and Late Recurrences in AF Cryoablation Introduction within the blanking period (early recurrences) are common after atrial fibrillation (AF) ablation by pulmonary vein isolation (PVI), but their clinical significance is still controversial. We aimed at evaluating of within‐blanking recurrences 12‐month follow‐up cryoballoon (CB) PVI, to assess real procedural success rate continuous monitoring cardiac rhythm. Methods Results Sixty consecutive patients (34 paroxysmal, 56.7%) underwent...

10.1111/jce.13190 article EN Journal of Cardiovascular Electrophysiology 2017-02-17
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