About
Contact & Profiles
A5011442048
Research Areas
- Signaling Pathways in Disease
- Viral Infectious Diseases and Gene Expression in Insects
- Nerve injury and regeneration
Columbia University
2017
Brain-derived neurotrophic factor (BDNF) and its receptor, tropomyosin-related kinase B (TrkB), have emerged as key regulators of brain plasticity represent disease-modifying targets for several disorders, including Alzheimer's disease major depressive disorder. Because poor pharmacokinetic properties BDNF, the interest in small-molecule TrkB agonists modulators is high. Several compounds been reported to act agonists, their increasing use various nervous system disorder models creates...
10.1126/scisignal.aal1670
article
EN
Science Signaling
2017-08-22
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