A5068907012- Dialysis and Renal Disease Management
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Metabolism and Genetic Disorders
- Renal function and acid-base balance
- Blood Pressure and Hypertension Studies
- Central Venous Catheters and Hemodialysis
- Chronic Kidney Disease and Diabetes
- Parathyroid Disorders and Treatments
- Renal Diseases and Glomerulopathies
- Vascular Procedures and Complications
- Renal and Vascular Pathologies
- Pharmacological Effects and Toxicity Studies
- Electrolyte and hormonal disorders
- Abdominal vascular conditions and treatments
- Drug-Induced Hepatotoxicity and Protection
- Poisoning and overdose treatments
- Diet and metabolism studies
- Potassium and Related Disorders
- Eosinophilic Disorders and Syndromes
- Acute Kidney Injury Research
- Bipolar Disorder and Treatment
- Methemoglobinemia and Tumor Lysis Syndrome
- Systemic Sclerosis and Related Diseases
- Neurological and metabolic disorders
- Muscle and Compartmental Disorders
Harvard University
2015-2025
The University of Texas Southwestern Medical Center
1996-2025
Massachusetts General Hospital
2014-2023
Brigham and Women's Hospital
2017-2018
Pediatric Nephrology of Alabama
2017
Baylor University Medical Center
2001-2014
Harvard University Press
2014
Health Affairs
2011
Buffalo General Medical Center
2010
Dallas Nephrology Associates
1996-2009
Collapsing focal segmental glomerulosclerosis (FSGS) is a distinct clinicopathologic entity seen most commonly in young African American patients who present with renal insufficiency and nephrotic syndrome. The only epidemiologic factor previously linked to collapsing FSGS HIV infection. Here findings are reported for distinctive population of seven patients, were older, Caucasian, negative developed during active treatment malignancy (multiple myeloma six metastatic breast carcinoma one)....
Atrial natriuretic peptide, a hormone synthesized by the cardiac atria, increases glomerular filtration rate dilating afferent arterioles while constricting efferent arterioles. It has been shown to improve filtration, urinary output, and renal histopathology in laboratory animals with acute dysfunction. Anaritide is 25-amino-acid synthetic form of atrial peptide.
Arteriovenous graft stenosis leading to thrombosis is a major cause of complications in patients undergoing hemodialysis. Procedural interventions may restore patency but are costly. Although there no proven pharmacologic therapy, dipyridamole be promising because its known vascular antiproliferative activity.We conducted randomized, double-blind, placebo-controlled trial extended-release dipyridamole, at dose 200 mg, and aspirin, 25 given twice daily after the placement new arteriovenous...
ObjectiveEarly thrombosis (ET) contributes to autogenous arteriovenous fistula (AVF) failure. We studied patients undergoing AVF placement in the Hemodialysis Fistula Maturation Study, a prospective, observational cohort study, using nested case-control analysis identify preoperative and intraoperative predictors of ET.MethodsET cases were compared with controls, who matched for gender, age, diabetes, dialysis status, surgeon volume. ET was defined as diagnosed by physical examination or...
Hyperammonemic encephalopathy is an uncommon but severe complication of the Roux-en-Y gastric bypass surgery for obesity. Mechanisms underlying this are incompletely understood, resulting in delayed recognition and management. This study evaluated common laboratory findings possible etiology hyperammonemic after successful surgery.A retrospective review 20 patients identified through our own clinical practice was conducted, with addition similar cases from other institutions...
Abstract The pathogenesis of arteriovenous fistula (AVF) maturation failure is unclear. We evaluated the associations wall shear stress (WSS) with subsequent AVF remodeling and clinical using regression models in this prospective cohort study. Participants underwent duplex ultrasound at postoperative Day 1, Week 2, 6 to measure blood flow rate diameter draining vein proximal artery. median WSS 602 participants decreased from 1 (from 33.4 21.6 dyne/cm 2 ) but did not change noticeably for...
1MGH and Harvard Medical School 2Division of Nephrology, Department Medicine, Massachusetts General Hospital, Boston, MA This is an open access article distributed under the terms Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it permissible to download share work provided properly cited. The cannot be changed in any way or used commercially without permission from journal.
Disseminated adenovirus (ADV) infection in solid organ transplant patients is associated with high mortality. Limited studies have shown benefit from using cidofovir (CDV), as well intravenous immunoglobulin (IVIG). In this study, we report 2 renal who presented fever and pulmonary infiltrates. Both continued to worsen despite antibiotic therapy. Bronchoalveolar lavage viral culture serum polymerase chain reaction (PCR) were positive for ADV. Patients treated CDV, IVIG, reduction...
Background Hyperhemolysis is a serious transfusion reaction, most often described in patients with hemoglobinopathies. characterized by the destruction of host red blood cells ( RBCs ), addition to donor , via an unknown mechanism. Study Design and Methods We present case 58‐year‐old woman treated human immunodeficiency virus normal hemoglobin Hb ) electrophoresis who developed hyperhemolysis setting delayed hemolytic reaction DHTR ). Results The patient was ABO group B had previously...
"5-Oxoproline (Pyroglutamic) Acidosis Associated with Chronic Acetaminophen Use." Baylor University Medical Center Proceedings, 23(1), pp. 19–20
Worldwide, there have been <25 reported cases of hyperammonemic encephalopathy associated with Roux-en-Y gastric bypass surgery in the absence cirrhosis. We describe a 42-year-old woman who presented subacute but progressive neurological decline late her postoperative course, which deteriorated despite multiple conservative and aggressive measures, including hemodialysis, an attempt to reduce measured plasma ammonia levels. This syndrome represents serious, underrecognized, potentially...