Mathew J. Thomas

ORCID: 0000-0003-2820-151X
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About
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Research Areas
  • Retinal Development and Disorders
  • Transplantation: Methods and Outcomes
  • Retinal Diseases and Treatments
  • Surgical Simulation and Training
  • Complement system in diseases
  • Yersinia bacterium, plague, ectoparasites research
  • Corneal surgery and disorders
  • Health and Conflict Studies
  • Viral Infections and Immunology Research
  • Abdominal vascular conditions and treatments
  • Zoonotic diseases and public health
  • Viral Infections and Outbreaks Research
  • Simulation-Based Education in Healthcare
  • Global Security and Public Health
  • Pleural and Pulmonary Diseases
  • CRISPR and Genetic Engineering
  • Mechanical Circulatory Support Devices
  • Herpesvirus Infections and Treatments
  • Corneal Surgery and Treatments
  • Mosquito-borne diseases and control
  • Foreign Body Medical Cases
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Viral-associated cancers and disorders
  • Animal Disease Management and Epidemiology

University of Nevada, Reno
2022-2024

Jacksonville College
2024

Mayo Clinic in Florida
2018-2024

WinnMed
2024

Sierra Eye Associates
2023

Regenxbio (United States)
2023

Betsi Cadwaladr University Health Board
2021

Cardiff and Vale University Health Board
2021

University of Washington
2013

Office of International Affairs
2012

Abstract Management of vitreoretinal disorders (e.g., neovascular age-related macular degeneration [nAMD] and diabetic edema [DME]) have assumed the standard therapy lifelong anti-VEGF injections with drugs like aflibercept, brolucizumab, ranibizumab bevacizumab. However, burden imposed on patients is a major deterrent for continual recovery. Faricimab, bispecific antibody, blocking both VEGF-A Ang-2 molecules, produces comparable functional anatomical results, less injections, significantly...

10.1186/s40942-024-00525-9 article EN cc-by International Journal of Retina and Vitreous 2024-01-17

ABSTRACT The complete sequence of retroperitoneal fibromatosis-associated herpesvirus Macaca nemestrina (RFHVMn), the pig-tailed macaque homolog Kaposi's sarcoma-associated (KSHV), was determined by next-generation analysis a sarcoma (KS)-like tumor. Colinearity genes observed with KSHV genome, and core had strong homology to corresponding genes. RFHVMn lacked homologs open reading frame 11 (ORF11) ORFs K5 K6, which appear have been generated duplication K3 K4 after divergence RFHV....

10.1128/jvi.02331-13 article EN Journal of Virology 2013-10-10

Aziz, Aamir A. BS; Khan, Hannah MPH; Khanani, Zoha A.; Thomas, Mathew J. Huma; Ahmed, Abrahim Gahn, Greggory M. MD; Arshad MD, MA Author Information

10.1097/iio.0000000000000517 article EN International Ophthalmology Clinics 2023-12-26

Introduction Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) and a leading cause vision loss for which there are currently two FDA-approved treatments (pegcetacoplan avacincaptad pegol). The complement system, major effector arm innate adaptive immunity, has been implicated in the pathogenesis GA. This review aims to provide comprehensive overview mechanisms underlying dysregulation GA current therapeutic strategies treat via targeting system.

10.1080/17469899.2023.2286607 article EN Expert Review of Ophthalmology 2023-11-21

Lung volume reduction surgery (LVRS) has historically been performed as a bilateral operation. We aimed to compare the short-term morbidity and mortality between unilateral LVRS.

10.21037/jtd-23-1655 article EN Journal of Thoracic Disease 2024-10-01

Introduction/Background: Patients with heart failure and those waiting for a transplant often experience significant decrease in their ability to perform daily activities exercise, leading lower quality of life. Although exercise-based cardiac rehabilitation (EBCR) is possible treatment option, its effectiveness has not been well measured, resulting limited adoption. Research Questions/Hypothesis: Could physical before receiving improve functional status better outcomes? Goals/Aims: Our...

10.1161/circ.150.suppl_1.4146528 article EN Circulation 2024-11-12

10.1016/j.ajo.2022.10.005 article EN American Journal of Ophthalmology 2022-10-14

Abstract Introduction Studies that have reviewed technologies including haptic feedback and virtual reality indicate the usefulness of simulation. However, these are not universally available. Less technologically innovative simulation methods utilise learning environment, equipment presentation can still effectively support surgical teaching. A review was undertaken to assess effect lower fidelity on skill acquisition. Method Two courses enrolled 12 14 respectively, with trainees ranging in...

10.1093/bjs/znab117.057 article EN British journal of surgery 2021-03-01
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