A5089215404- Various Chemistry Research Topics
- Chemical Synthesis and Reactions
- Coordination Chemistry and Organometallics
- Asymmetric Synthesis and Catalysis
- Inorganic and Organometallic Chemistry
- Catalytic Cross-Coupling Reactions
- Asymmetric Hydrogenation and Catalysis
- Toxin Mechanisms and Immunotoxins
- Analytical Chemistry and Chromatography
- Transgenic Plants and Applications
- Herbal Medicine Research Studies
- History and advancements in chemistry
- Chemical Reactions and Isotopes
- Mass Spectrometry Techniques and Applications
- Sulfur-Based Synthesis Techniques
- Microfluidic and Capillary Electrophoresis Applications
- Fluorine in Organic Chemistry
- Oxidative Organic Chemistry Reactions
- Synthetic Organic Chemistry Methods
- Catalytic C–H Functionalization Methods
- Synthesis and Catalytic Reactions
- Catalysis for Biomass Conversion
- Synthesis and characterization of novel inorganic/organometallic compounds
- Advanced Chemical Sensor Technologies
- Chemistry and Chemical Engineering
Indiana State University
1996-2017
Purdue University West Lafayette
1977
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRegiospecific 1,4-addition with Grignard-derived mixed triorganozincate reagentsRichard A. Kjonaas and Ronald K. HofferCite this: J. Org. Chem. 1988, 53, 17, 4133–4135Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August 1988https://pubs.acs.org/doi/10.1021/jo00252a055https://doi.org/10.1021/jo00252a055research-articleACS PublicationsRequest reuse permissionsArticle...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRegioselective 1,4-addition to .alpha.,.beta.-unsaturated ketones with Grignard reagents mediated by (N,N,N',N'-tetramethylethylenediamine)zinc(II) chlorideRichard A. Kjonaas and Edward J. VawterCite this: Org. Chem. 1986, 51, 21, 3993–3996Publication Date (Print):October 1, 1986Publication History Published online1 May 2002Published inissue 1 October...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarbopalladation-depalladation of allylic amines and sulfidesRobert A. Holton Richard KjonaasCite this: J. Am. Chem. Soc. 1977, 99, 12, 4177–4179Publication Date (Print):June 1, 1977Publication History Published online1 May 2002Published inissue 1 June 1977https://pubs.acs.org/doi/10.1021/ja00454a057https://doi.org/10.1021/ja00454a057research-articleACS PublicationsRequest reuse permissionsArticle Views303Altmetric-Citations42LEARN ABOUT THESE...
This is a correction article.
Vaccine efficacy depends significantly on the use of appropriate adjuvant(s) in formulation. Phytol, a dietary diterpene alcohol, is similar structure to naturally occurring isoprenoid adjuvants; but little known its adjuvanticity. In this report, we describe relative safety and phytol hydrogenated derivative PHIS-01 compared commercial adjuvants. We tested adjuvant properties using formulation consisting either hapten, phthalate-conjugated protein, keyhole limpet hemocyanin (KLH), or...
A method for the synthesis of ibuprofen in introductory organic chemistry laboratory courses is reported. This experiment requires two 3-h lab sessions. All reactions and techniques are a standard part any course. In first session, students reduce p-isobutylacetophenone to an alcohol then convert this corresponding chloride. second chloride Grignard reagent, which carboxylated protonated give ibuprofen. Although final yield modest, procedure offers both practicability reliability....
Adjuvants are known to significantly enhance vaccine efficacy. However, commercial adjuvants often have limited use because of toxicity in humans. The objective this study was determine the comparative effectiveness a diterpene alcohol, phytol and its hydrogenated derivative PHIS-01, relative incomplete Freund's adjuvant (IFA), commonly used augmenting protective immunity mice against E. coli S. aureus, terms inflammatory cytokines.Vaccines, consisting heat-attenuated or aureus either two...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBiaryl synthesis via coupling of arylthallium bis(trifluoroacetates) with a catalytic amount lithium tetrachloropalladateRichard A. Kjonaas and David C. ShubertCite this: J. Org. Chem. 1983, 48, 11, 1924–1925Publication Date (Print):June 1, 1983Publication History Published online1 May 2002Published inissue 1 June 1983https://pubs.acs.org/doi/10.1021/jo00159a033https://doi.org/10.1021/jo00159a033research-articleACS PublicationsRequest reuse...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Discovery-Based Experiment Involving Rearrangement in the Conversion of Alcohols to Alkyl HalidesRichard A. Kjonaas and Ryand J. F. Tucker View Author Information Department Chemistry, Indiana State University, Terre Haute, IN 47809Cite this: Chem. Educ. 2008, 85, 1, 100Publication Date (Web):January 2008Publication History Received3 August 2009Published online1 January 2008Published inissue 1...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAcid-Catalyzed Isomerization of Carvone to CarvacrolRichard A. Kjonaas and Shawn P. Mattingly View Author Information Department Chemistry, Indiana State University, Terre Haute, IN 47809Cite this: J. Chem. Educ. 2005, 82, 12, 1813Publication Date (Web):December 1, 2005Publication History Received3 August 2009Published online1 December 2005Published inissue 1...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Baeyer–Villiger Oxidation with Trifluoroacetic Acid and Household Sodium PercarbonateRichard A. Kjonaas Anthony E. Clemons View Author Information Department of Chemistry, Indiana State University, Terre Haute, IN 47809Cite this: J. Chem. Educ. 2008, 85, 6, 827Publication Date (Web):June 1, 2008Publication History Received3 August 2009Published online1 June 2008Published inissue 1...
A microscale isotopic labeling experiment is described for the introductory organic chemistry laboratory course wherein half of students use sodium borohydride (NaBH4) and other borodeuteride (NaBD4) to reduce acetophenone 1-phenylethanol then compare spectral data. The cost reasonable, well-suited serve as a first experience with 1H NMR spectroscopy, infrared and/or mass spectrometry. No special apparatus are required reaction. entire experiment, including an extensive prelab lecture...
A kinetic isotope effect (KIE) experiment is described for the physical chemistry laboratory. Students conduct a hypochlorite (household bleach) oxidation of an equimolar mixture 1-phenylethanol and 1-deuterio-1-phenylethanol to acetophenone. The reaction occurs in biphasic follows first-order kinetics with respect either isotopomer 1-phenylethanol. Reaction progress measured by gas chromatography–mass spectrometry (GC–MS). Alternatively, could be conducted each serially followed GC alone....
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKetovinylation of arylthallium compounds catalyzed by lithium tetrachloropalladateRichard A. KjonaasCite this: J. Org. Chem. 1986, 51, 19, 3708–3710Publication Date (Print):September 1, 1986Publication History Published online1 May 2002Published inissue 1 September 1986https://pubs.acs.org/doi/10.1021/jo00369a031https://doi.org/10.1021/jo00369a031research-articleACS PublicationsRequest reuse permissionsArticle Views108Altmetric-Citations12LEARN...
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTSimple Apparatus for Vacuum FiltrationDenis M. Zhilin*† and Richard A. Kjonaas‡View Author Information† Moscow Institute Open Education, 125167, Aviacionnyj per., 6 Moscow, Russia‡ Department of Chemistry Physics, Indiana State University, Terre Haute, Indiana, 47809, United States*E-mail: [email protected]Cite this: J. Chem. Educ. 2013, 90, 1, 142–143Publication Date (Web):October 15, 2012Publication History Published online15 October...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNumber of oxidations relative to methylene: A convenient method recognizing and quantifying organic oxidation-reductionRichard A. Kjonaas Cite this: J. Chem. Educ. 1986, 63, 4, 311Publication Date (Print):April 1, 1986Publication History Received3 August 2009Published online1 April 1986Published inissue 1 1986https://doi.org/10.1021/ed063p311Request reuse permissionsArticle Views120Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn analogy for solubility: Marbles and magnetsRichard A. Kjonaas Cite this: J. Chem. Educ. 1984, 61, 9, 765Publication Date (Print):September 1, 1984Publication History Received3 August 2009Published online1 September 1984Published inissue 1 1984https://doi.org/10.1021/ed061p765RIGHTS & PERMISSIONSArticle Views171Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA simple apparatus for laboratory dry ice productionMyong-Ku Ahn and Richard A. Kjonaas Cite this: J. Chem. Educ. 1985, 62, 1, 90Publication Date (Print):January 1985Publication History Received3 August 2009Published online1 January 1985Published inissue 1 1985https://doi.org/10.1021/ed062p90RIGHTS & PERMISSIONSArticle Views128Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads...
By placing a piece of chewing gum (Wrigley's) or crushedpiece hard candy (LifeSavers Runts) into vial, followedby GC/MS analysis five microliter sample the headspace,students are able to identify several volatile flavoringcomponents which present. The experiment has been usedsuccessfully with sophomore organic chemistry students, and withvisiting groups talented high school students over threeyear period. Identification is simplified by handing out listof structural formulas some likely...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA study of the Lucas testRichard A. Kjonaas and Bernie Riedford Cite this: J. Chem. Educ. 1991, 68, 8, 704Publication Date (Print):August 1, 1991Publication History Received3 August 2009Published online1 1991Published inissue 1 1991https://doi.org/10.1021/ed068p704RIGHTS & PERMISSIONSArticle Views2883Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are COUNTER-compliant sum full text article downloads since November 2008 (both PDF HTML)...