A5101420489- Growth Hormone and Insulin-like Growth Factors
- Thyroid Disorders and Treatments
- Pituitary Gland Disorders and Treatments
- Glaucoma and retinal disorders
- Diabetes and associated disorders
- Diabetes Management and Research
- Pancreatic function and diabetes
- Adrenal and Paraganglionic Tumors
- Effects and risks of endocrine disrupting chemicals
- Cardiovascular Disease and Adiposity
- Vitamin D Research Studies
- Carcinogens and Genotoxicity Assessment
- Retinal Diseases and Treatments
- Diet and metabolism studies
- Neonatal Health and Biochemistry
- Nutrition, Health and Food Behavior
- Neuroscience of respiration and sleep
- Obesity, Physical Activity, Diet
- Thyroid Cancer Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Childhood Cancer Survivors' Quality of Life
- Neuroblastoma Research and Treatments
- Food Quality and Safety Studies
- Birth, Development, and Health
- Body Image and Dysmorphia Studies
Seoul National University
2014-2025
Seoul National University Children's Hospital
2015-2024
Seoul National University Hospital
2021-2023
Kyungpook National University Hospital
2022
Rural Development Administration
2021
Kyungpook National University Medical Center
2020
Korea Maritime Institute
2014
Inje University
2013
Inje University Ilsan Paik Hospital
2010-2012
Korea University
2007-2009
Over the last decades, onset of puberty in girls has occurred earlier, but tempo pubertal progression been relatively slower, resulting a younger age at without change menarche. Sufficient energy availability and adiposity contribute to early development, environmental factors, such as endocrine-disrupting chemicals (EDCs), may affect not only control balance, also reproduction. EDCs are hormonally active substances that can perturb by acting both peripherally on target organs, adipose...
Growth charts are important tools used to evaluate the growth status of children and estimate nutritional health general population. In Korea, national standardized were updated in 2017. However, developed by World Health Organization (WHO) being adopted for under 3 years age despite a lack evidence their applicability Koreans. Here we aimed collect accurate physical measurement data, develop infants toddlers based on breastfeeding, feasibility adopting WHO standards as reference Korea....
Microalbuminuria is associated with increased risk of renal disease and cardiovascular diseases even in non-diabetic subjects. High incidence rates microalbuminuria have been found a number population-based studies. However, the prevalence factors general population Korea are unclear.The present study was performed to estimate investigate adult using Fifth National Health Nutrition Examination Survey (KNHANES V-2) data from 2011.A total 5,202 participants (mean age, 45.6 years; men, 2,337;...
Discontinuing growth hormone (GH) treatment during the transition to adulthood has been associated with adverse health outcomes in patients childhood-onset deficiency (CO-GHD). This study investigated metabolic changes interrupting GH adolescents CO-GHD period.This included 187 who were confirmed have adult GHD and treated at six academic centers Korea. Data on clinical parameters, including anthropometric measurements, profiles, bone mineral density (BMD) end of childhood treatment,...
Hyperuricemia has a suspected relationship with hypertension, metabolic syndrome, kidney disease, and cardiovascular disease. Endocrine disruptors may affect uric acid metabolism; however, few epidemiologic studies have been performed in children regarding newly developed bisphenol A (BPA) substitutes. We evaluated the associations between BPA, S (BPS), F (BPF) exposure serum concentrations 6-year-old Korean children.From Environment Development of Children cohort study, six-year-old (N =...
We hypothesized that overweight or obese children might develop type 1 diabetes mellitus (T1DM) early despite residual beta-cell function. Factors independently associated with preservation of C-peptide level were analyzed.We retrospectively reviewed the medical data 135 aged 2.1-16.5 years autoimmune T1DM. Body mass index (BMI), pubertal stage, and glycosylated hemoglobin (HbA1c) levels evaluated. Patients assigned to underweight (22.2%), normal weight (63.7%), (14.1%) groups according...
Background: Obesity, a chronic low-grade inflammatory state, increases the risk of cardiovascular disease. Elevated high-sensitivity C-reactive protein (hs-CRP) levels are associated with disease, type 2 diabetes, and metabolic syndrome in adults. This study aimed to determine association hs-CRP cardiometabolic factors, including obesity, prediabetes, hypertension, dyslipidemia, nationally representative data Korean youth. Methods: Anthropometric, biochemical, physical activity (PA),...
Background: Endocrinopathy is a risk factor for slipped capital femoral epiphysis (SCFE). We aimed to determine (1) the incidence of endocrinopathy-associated SCFE compared with that non-endocrinopathy-associated SCFE, (2) whether increases number deficient hormones, and (3) clinical characteristics SCFE. Methods: conducted population-based cohort study using nationwide database in South Korea. All new diagnoses endocrinopathy or between 2002 2019 children born 2005 were identified. The was...
Adequate iodine intake is essential for growing children, as both deficient and excessive status can result in thyroid dysfunction. We investigated the its association with function 6-year-old children from South Korea. A total of 439 aged 6 (231 boys 208 girls) were Environment Development Children cohort study. The test included free thyroxine (FT4), triiodothyronine (T3), thyroid-stimulating hormone (TSH). Urine was evaluated using urine concentration (UIC) morning spot categorized into...
The rates, patterns and associated factors for false-positive classification of deviation maps by Cirrus optical coherence tomography (OCT) have been reported. However, research on OCT layer-by-layer is lacking. We aimed to determine the rates segmented macular layers retinal nerve fiber layer (RNFL) Spectralis OCT, identify maps. 118 healthy eyes normal participants who had undergone imaging were included. False-positive was determined area location yellow or red color-coded regions map....
Purpose Hypothalamic obesity in childhood-onset (CO-) craniopharyngioma patients may predispose to nonalcoholic fatty liver disease (NAFLD). This study reviewed the characteristics of NAFLD associated with CO-craniopharyngioma. Methods retrospectively 75 who underwent surgery for while younger than 15 years age between 2000 and 2016. Results Elevated aspartate aminotransferase (AST) or alanine (ALT) above 40 IU/L was observed 51 (68%) CO-craniopharyngioma patients. Imaging studies were...
Abstract To evaluate histopathological characteristics of conjunctival pigmented lesions and analyze clinical features related to histologic classification in Asian population, we analyzed medical records, anterior segment photographs, histological specimen 85 eyes who had undergone biopsy for at Seoul National University Hospital between 1999 2018. Compound nevus was the most common type (67.1%), followed by melanocytic intraepithelial neoplasia (primary acquired melanosis)(11.8%),...
Unfavorable Course of Subclinical Hypothyroidism in Children with Hashimoto's Thyroiditis Compared to Those Isolated Non-Autoimmune Hyperthyrotropinemia hypothyroidism (SCH) is a common problem pediatric population, and the natural history SCH varies depending on its etiology.Whether thyroiditis (HT) negatively affects course was investigated patients without concomitant diseases.Predictors for levothyroxine medication were also evaluated.Medical records 109 children (91 girls, 5-18 years)...