A5000320934- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- S100 Proteins and Annexins
- Intracerebral and Subarachnoid Hemorrhage Research
- Long-Term Effects of COVID-19
- Autoimmune Neurological Disorders and Treatments
- Neurological disorders and treatments
- Vasculitis and related conditions
- Peripheral Neuropathies and Disorders
- Neurological and metabolic disorders
- Retinal and Optic Conditions
- Genetic Neurodegenerative Diseases
- Neurogenetic and Muscular Disorders Research
- Parkinson's Disease Mechanisms and Treatments
- COVID-19 Clinical Research Studies
- Stroke Rehabilitation and Recovery
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Retinal Imaging and Analysis
- Cardiovascular Health and Disease Prevention
- Inflammatory Myopathies and Dermatomyositis
- Sleep and related disorders
- Otitis Media and Relapsing Polychondritis
- Blood Coagulation and Thrombosis Mechanisms
- Obstructive Sleep Apnea Research
- Protease and Inhibitor Mechanisms
All India Institute of Medical Sciences
2015-2024
All India Institute of Medical Sciences Raipur
2019-2024
All India Institute of Medical Sciences Bhopal
2019-2024
Neurology, Inc
2022-2023
Rajendra Institute of Medical Sciences
2022
Banaras Hindu University
2018
Institute of Medical Sciences
2018
Post Graduate Institute of Medical Education and Research
2017
In-Q-Tel
2015
Abstract There is a pressing clinical need for thrombolytic agents that can effectively disaggregate arterial thrombi in acute ischemic stroke without significantly increasing the risk of bleeding. This pilot study aimed to investigate safety and efficacy N -acetylcysteine (NAC) as an adjunctive therapy intravenous recombinant tissue plasminogen activator (rtPA or alteplase). A randomized, open-label, blinded assessor was conducted. Patients presenting with within 4.5 h from onset were...
Early prognostication of patient outcomes in intracerebral hemorrhage (ICH) is critical for care. We aim to investigate protein biomarkers’ role prognosticating ICH patients. assessed 22 biomarkers using targeted proteomics serum samples obtained from the dataset (N = 150). defined poor as modified Rankin scale score 3–6. incorporated clinical variables and regression models random forest-based machine learning algorithms predict mortality. report Odds Ratio (OR) or Hazard (HR) with 95%...
Abstract Primary CNS Vasculitis (PCNSV) is a rare inflammatory disorder affecting the blood vessels of central nervous system. Patients present with combination headaches, seizures, and focal neurological deficits. There usually diagnostic delay. Treatment based on observational studies expert opinion. Our objective was to identify clinical, laboratory, neuroimaging, pathologic or management-related associations 2 year outcome in patients primary vasculitis. We conducted cohort study at...
[13][14][15][16][17][18] Numerous studies have investigated the association of IL-6 G174C and G572C gene polymorphisms in relation to various ischaemic atherosclerotic cardiovascular diseases.Associations been reported between GG genotype asymptomatic carotid artery atherosclerosis, [19][20][21][22] risk coronary heart disease, 23 peripheral arterial occlusive 24 multiinfarct dementia, 25 longer hospital intensive care unit stay after bypass graft surgery. 26However, other found associations...
Abstract Primary CNS Vasculitis (PCNSV) is a rare, diverse, and polymorphic blood vessel inflammatory condition. Due to its rarity, clinical variability, heterogeneous imaging results, lack of definitive laboratory markers, PCNSV diagnosis challenging. This retrospective cohort analysis identified patients with histological PCNSV. Demographic data, presentation, neuroimaging studies, histopathologic findings were recorded. We enrolled 56 positive biopsy vasculitis. Most had cerebral...
To determine the association of smartphone use with occurrence new-onset headache and/or increased severity headaches in patients primary headache.In a cross-sectional study between June 2017 and December 2018, were divided into 2 groups: users (SUs) non-smartphone (NSUs). A questionnaire was administered for characteristics treatment taken. The objective to or increase severity. secondary any differences requirement acute medication prophylaxis.Four hundred included study, which 194 NSUs...
Recent developments in high-throughput proteomic approach have shown the potential to discover biomarkers for diagnosing acute stroke and elucidate pathomechanisms specific different subtypes. We aimed determine blood-based protein diagnose total (IS+ICH) from healthy controls, ischemic (IS) intracerebral hemorrhage (ICH) control subjects within 24 h using a discovery-based SWATH-MS approach.In this discovery phase study, serum samples were collected (IS & ICH) patients controls subjected...
(1) Background: During the second wave of COVID-19, India faced a rapid and sudden surge not only COVID19-delta variant cases but also mucormycosis, making infection even more fatal. We conducted study to determine factors associated with occurrence mucormycosis in patients COVID-19. (2) Methods: This case-control comprised 121 patients; 61 (mucormycosis COVID-19) 60 controls. Patients were included from April 10, 2021 onwards. Follow-up was after about 90 days health status recorded based...
Stroke is a devastating and disabling cerebrovascular disease with some amount of residual deficit leading to economic loss. Recent Indian studies have shown stroke prevalence rate 471.58/100,000 populations. Hypertension has been known be the main risk factor for causing stroke.To investigate hypertension in first-ever patients its comparison previous registry.The study was hospital-based cross-sectional study. Consecutive patients, who were admitted Neurology ward All India Institute...