Shiwen Chen

ORCID: 0000-0003-2850-5310
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About
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Research Areas
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Aquaculture disease management and microbiota
  • Aquaculture Nutrition and Growth
  • Acute Ischemic Stroke Management
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Intracranial Aneurysms: Treatment and Complications
  • Venous Thromboembolism Diagnosis and Management
  • Neurosurgical Procedures and Complications
  • Cerebrospinal fluid and hydrocephalus
  • S100 Proteins and Annexins
  • Trauma and Emergency Care Studies
  • Data-Driven Disease Surveillance
  • Head and Neck Surgical Oncology
  • Spinal Fractures and Fixation Techniques
  • Cerebrovascular and Carotid Artery Diseases
  • HIV/AIDS Research and Interventions
  • Advanced Cellulose Research Studies
  • Adenosine and Purinergic Signaling
  • Anomaly Detection Techniques and Applications
  • Ginseng Biological Effects and Applications
  • Spine and Intervertebral Disc Pathology
  • RNA Research and Splicing
  • Wound Healing and Treatments
  • COVID-19 epidemiological studies
  • Electrospun Nanofibers in Biomedical Applications

Ministry of Agriculture and Rural Affairs
2022-2025

Shanghai Ocean University
2022-2025

Shanghai Sixth People's Hospital
2011-2024

Shanghai Jiao Tong University
2013-2024

Guangxi Medical University
2023-2024

China Three Gorges University
2024

China Agricultural University
2013-2024

Kerala Veterinary and Animal Sciences University
2024

Southwest Minzu University
2024

Yichang Central People's Hospital
2024

The second-generation of iron supplements is known for its instability, thus leading to the emergence polysaccharide complexes as a novel third-generation supplement, which has garnered significant scholarly attention. Yet, there limited body academic literature on stability and biological activity complexes. objective this study investigate stability, release Fe3+, fermented Tremella after complexation with Fe3+ in order address research gaps field. combination was confirmed successful by...

10.1016/j.lwt.2024.115775 article EN cc-by-nc-nd LWT 2024-01-19

Previous studies have demonstrated that patients with traumatic brain injury (TBI) who also progressive hemorrhagic (PHI), a higher risk of clinical deterioration and worse outcomes than do TBI without PHI. Therefore, the early prediction PHI occurrence is useful to evaluate status improve outcomes. The objective this study was develop validate prognostic model uses information available at admission determine likelihood after TBI. Retrospectively collected data were used logistic regression...

10.1089/neu.2011.2233 article EN Journal of Neurotrauma 2012-05-08

To improve the efficacy and safety of dural repair in neurosurgical procedures, a new material derived from bacterial cellulose (BC) was evaluated rabbit model with defects. We prepared artificial dura mater using which incubated fermented Acetobacter xylinum. The defects were repaired BC membranes. All surgeries performed under sodium pentobarbital anesthesia, all efforts made to minimize suffering. animals humanely euthanized by intravenous injection phenobarbitone, at each time point,...

10.3390/ijms150610855 article EN International Journal of Molecular Sciences 2014-06-16

Progressive epidural hematoma (PEDH) after head injury is often observed on serial computerized tomography (CT) scans. Recent advances in imaging modalities and treatment might affect its incidence outcome. In this study, PEDH was 9.2% of 412 trauma patients whom two CT scans were obtained within 24 hours injury, a majority cases, it developed 3 days injury. multivariate logistic regression, patient gender, age, Glasgow Coma Scale (GCS) score at admission, skull fracture not associated with...

10.1155/2012/134905 article EN cc-by Emergency Medicine International 2012-01-01

Abstract Purpose: We hypothesize that changes in the transcription of up-regulated genes are biologically meaningful and may be linked to variations tumor behavior clinical features. This study aimed find individual responsible for clinicopathologic human colorectal cancer. Experimental Design: Genes concurrently four microarray experiments were taken as candidate genes; 20 verified using real-time reverse transcription-PCR these experiments, along with 27 new samples. The presence or...

10.1158/1055-9965.epi-04-0396 article EN Cancer Epidemiology Biomarkers & Prevention 2005-02-01

Early estimation of prognosis for the patient with traumatic brain injury is an important factor in making treatment decisions, resource allocation, classify patients, or communicating family. We aimed to develop and validate practical prognostic models mortality at 30 days 6 months unfavorable outcome after moderate severe injury.Retrospectively collected data from our department were used outcome. developed four based on admission predictors logistic regression analysis. The performance...

10.1097/ta.0b013e31824b00ac article EN Journal of Trauma and Acute Care Surgery 2012-06-28

Yeast β-glucan (YG) possess an extensive range of biological activities, such as the inhibition oxidation, but poor water solubility macromolecular YG limits its application. In this study, through combined degradation ultrasonic waves and H2O2, optimization main process parameters for solubilizing by response surface methodology (RSM), a new product YGUH was generated. The molecular weight, structural characteristics kinetics before after solubilization were evaluated. results showed that...

10.1016/j.ultsonch.2022.106210 article EN cc-by-nc-nd Ultrasonics Sonochemistry 2022-10-25

Abstract This study evaluated the effects of chenodeoxycholic acid (CDCA), a farnesoid X receptor (FXR) potential activator, on growth performance, antioxidant capacity, glucose metabolism, and inflammation in largemouth bass ( Micropterus salmoides ) (initial body weight: 5.45 ± 0.02 g) fed high-carbohydrate diet. Experimental diets included positive control (5 % α-starch), negative (10 two containing 10 α-starch supplemented with either 0.05 or 0.10 CDCA. After 8 weeks, diet reduced...

10.1017/s0007114525000583 article EN other-oa British Journal Of Nutrition 2025-03-24

Purpose: To discuss the repeated CT scanning in patients with traumatic brain injury (TBI) and to identify conditions under which this approach is necessary.Methods: One hundred seventy-one who suffered TBI but were not surgically treated divided into two groups: routine-repeat group (n = 89) non-routine-repeat 82). The patients' clinical characteristics compared. T-tests stepwise logistic regression used for analysis. Patients three groups according GCS scores determine need routinely...

10.3109/02699052.2012.667591 article EN Brain Injury 2012-05-09

Glioblastoma (GBM) is the most malignant nervous system tumor with an almost 100 % recurrence rate. Thymopoietin (TMPO) has been demonstrated to be upregulated in various tumors, including lung cancer, breast and so on, but its role GBM not reported. This study was aimed determine of TMPO GBM. Publicly available Oncomine dataset analysis used explore expression level specimens. Then knocked down cells using lentiviral system, knockdown efficacy further validated by real-time quantitative PCR...

10.1186/s12957-016-1018-y article EN cc-by World Journal of Surgical Oncology 2016-10-19
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