A5010830053- Bioactive Compounds and Antitumor Agents
- Natural product bioactivities and synthesis
- Cell death mechanisms and regulation
- Bioactive natural compounds
- Traditional Chinese Medicine Analysis
- Bioactive Natural Diterpenoids Research
- Plant biochemistry and biosynthesis
- Molecular Sensors and Ion Detection
- Chemical Reactions and Isotopes
- Genomics, phytochemicals, and oxidative stress
- Biological Activity of Diterpenoids and Biflavonoids
- Cancer, Lipids, and Metabolism
- Immune Response and Inflammation
- Metabolomics and Mass Spectrometry Studies
- Phytochemical compounds biological activities
- Biological and pharmacological studies of plants
Northeast Normal University
2013-2014
Jilin University
2014
Isoalantolactone, a medicinal plant-derived natural compound, is known to induce apoptosis in various cancer cell lines. However, its effect on prostate cells has not been addressed. Thus, we examined the effects of isoalantolactone cells. It was found that inhibits growth both androgen-sensitive (LNCaP) as well androgen-independent (PC3 and DU-145) dose-dependent manner. Furthermore, our results indicate isoalantolactone-induced PC3 associated with generation ROS dissipation mitochondrial...
Pinocembrin, (5, 7-dihydroxyflavanone), has been shown to possess anticancer activity against various cancer cells. However, its effect prostate cells remained enigmatic. In this study, for the first time, we investigated whether pinocembrin could inhibit growth of human MTT assay and flow cytometric analysis were performed examine effects on cell proliferation, cycle, apoptosis. The results revealed that attenuated viability both androgen-sensitive (LNCaP) as well androgen-independent (PC3...
Eriocalyxin B (EriB) has been shown to possess promising anticancer potential against various cancer cells. However, its effect bladder cells remained unexplored. In this study, for the first time, we investigated effects of EriB on cell proliferation, cycle, and apoptosis in T24 order examine apoptosis, performed MTT assay, flow cytometric analysis western blot. The results revealed that decreased viability Flow demonstrated markedly induced arrested cycle at G2/M phase a dose-dependent...
Urinary bladder cancer is one of the most commonly diagnosed urological malignancies worldwide. Dracorhodin perchlorate, anthocyanin red pigment, has been recently shown to induce apoptotic cell death in several types cells. However, there no report elucidating its effect on T24 In this study, for first time, we investigated effects dracorhodin perchlorate viability and apoptosis human DNA flow cytometric analysis demonstrated that markedly rendered cells a time-dependent manner....