A5040465178- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- Genomics and Phylogenetic Studies
- RNA Research and Splicing
- Nematode management and characterization studies
- Molecular Biology Techniques and Applications
- Insect symbiosis and bacterial influences
- Parasitic Diseases Research and Treatment
Université de Montpellier
2019-2023
Centre National de la Recherche Scientifique
2019-2023
Institut de Recherche pour le Développement
2019-2023
Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle
2019-2023
Centre National pour la Recherche Scientifique et Technique (CNRST)
2020
Agropolis International
2019
Molécules de Communication et Adaptation des Micro-organismes
2015
Sorbonne Université
2015
During the past twenty years, a number of molecular analyses have been performed to determine evolutionary relationships Onchocercidae, family filarial nematodes encompassing several species medical or veterinary importance. However, opportunities for broad taxonomic sampling scarce, and were based mainly on 12S rDNA coxI gene sequences. While being suitable differentiation, these mitochondrial genes cannot be used infer phylogenetic hypotheses at higher levels. In present study, 48 species,...
Gene paralogs are copies of an ancestral gene that appear after or full genome duplication. When two sister maintained in the genome, redundancy may release certain evolutionary pressures, allowing one them to access novel functions. Here, we focused our study on history three polypyrimidine tract binding protein genes (PTBP) and their concurrent evolution differential codon usage preferences (CUPrefs) vertebrate species. PTBP1-3 show high identity at amino acid level (up 80%) but display...
Abstract Codon Usage Preferences (CUPrefs) describe the unequal usage of synonymous codons at gene, genomic region or genome scale. Numerous indices have been developed to measure CUPrefs a sequence. We introduce normalized index calculate called COUSIN for COdon Similarity INdex. This compares query against those reference dataset and normalizes output over Null Hypothesis random codon usage. results can be easily interpreted, quantitatively qualitatively. exemplify use highlight its...
A bstract Gene paralogs are copies of an ancestral gene that appear after or full genome duplication. When two sister maintained in the genome, redundancy may release certain evolutionary pressures, allowing one them to access novel functions. Here, we focused our study on history three polypyrimidine tract binding protein genes ( PTBP ) and their concurrent evolution differential codon usage preferences (CUPrefs) vertebrate species. PTBP1-3 show high identity at amino acid level (up 80%),...