A5048755324- Antifungal resistance and susceptibility
- Tuberculosis Research and Epidemiology
- Bacterial Identification and Susceptibility Testing
- Mycobacterium research and diagnosis
- Diphtheria, Corynebacterium, and Tetanus
- Plant Pathogens and Fungal Diseases
- Insect and Pesticide Research
- Bee Products Chemical Analysis
- Mosquito-borne diseases and control
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Mycotoxins in Agriculture and Food
- Infections and bacterial resistance
- Fungal Infections and Studies
- Antimicrobial Resistance in Staphylococcus
- Infectious Diseases and Tuberculosis
- Nail Diseases and Treatments
- Forensic Entomology and Diptera Studies
- Complementary and Alternative Medicine Studies
- Plant Reproductive Biology
- Healthcare and Venom Research
- Clostridium difficile and Clostridium perfringens research
- Respiratory Support and Mechanisms
- Viral Infections and Vectors
- Insects and Parasite Interactions
Balıkesir University
2022-2024
Sağlık Bilimleri Üniversitesi
2017-2023
City Hospital
2022-2023
University of Health Science
2017-2023
Hacettepe University
2018-2022
State Hospital
2021
Military Medical Academy
2016-2017
University of Health Sciences
2017
Gülhane Askerî Tıp Akademisi
2016-2017
Erzurum Regional Training and Research Hospital
2017
Aspergillus fumigatus causes several diseases in humans and azole resistance A. strains is an important issue. The aim of this multicentre epidemiological study was to investigate the prevalence clinical environmental isolates Turkey.Twenty-one centres participated from 1 May 2018 October 2019. One participant each centre asked collect isolates. Azole screened for using EUCAST agar screening methodology (EUCAST E.DEF 10.1) confirmed by 9.3 reference microdilution method. Isolates with a...
Abstract The aim of this multicenter study was to evaluate the performance crystal violet decolorization assay (CVDA) for detection multidrug resistant tuberculosis (MDR-TB). This performed in 11 centers two phases. A total 156 isolates were tested INH and RIF resistance. In phase I, 106 clinical Center 1–7. 2, center 1–6, 8–11. Eighty six same I. Agreements 96.2–96.8% 98.1–98.7% I-II, respectively. Mean time obtain results I 14.3 ± 5.4 days. II, mean 11.6 3.5 Test obtained within 14days...
Abstract Background/aim : This prospective study aimed to determine the presence of most common carbapenemase genes, blaOXA-48, blaKPC, blaIMP, blaVIM and blaNDM on carbapenem resistant clinical K.pneumoniae E.coli isolates. Materials methods Isolates were selected according EUCAST guideline; gradient test disc diffusion with both meropenem ertapenem discs. Resistance rates these isolates other antimicrobial agents also examined by method. Carbapenem resistance gene investigated using...
Superficial fungal infections caused by
The frequency of invasive fungal infections shows a rising trend as well high morbidity and mortality. Among the causative agents, shift toward non-albicans Candida species including glabrata complex is being observed in several centers. Echinocandin resistance increasingly published; however, isolates presenting with an vitro have not yet been reported from Turkey. We, herein, report first FKS mutant phenotypically echinocandin-resistant C. clinical strains single center In 43-year-old...
Objective: The present study aimed to evaluate the performances of BACTEC MGIT 960 SL DST kit and GenoType MTBDRsl test for detecting second-line antituberculosis drug resistance in Multidrugresistant TB (MDR-TB) cases.Materials Methods: Forty-six MDR-TB strains were studied.Second-line resistances detected using test.The Middlebrook 7H10 agar proportion method was used as reference test. Results:The sensitivity specificity values both 100% amikacin, kanamycin, capreomycin (4 µg/mL),...
Royal jelly is a secretion of honeybees that actually for feeding bee larvae. It contains many bioactive substances such as jelleins, royalisin, major royal proteins and 10-hydroxy-2-decenoic acid. Recently, studies were published investigating activities jelly. In overall, found to have antioxidant, neurotrophic, antidiabetic, hypocholesterolemic, regulatory on blood pressure, antimicrobial, immunomodulatory, anti-tumor tissue-protective effects. These are strongly related each other cannot...
BACKGROUND Bloodstream infections are one of the major causes healthcare-associated morbidity and mortality. The present study aims to investigate prevalence microorganisms isolated from blood cultures evaluate susceptibilities antimicrobial agents in a tertiary center, Gulhane Training Research Hospital, Ankara, Turkey. METHODS Blood (BCs) were incubated BACTEC/9050 (Becton Dickinson, USA) (2007 - 2015) BacT/ALERT (bio-Merieux, France) (2014 2016) automated systems. PhoenixTM 100 system...
The frequency and variety of infections caused by fungi are increasing. However, changes intercenter regional differences observed in the distribution fungal species over years. It is important to update epidemiological data order enable early appropriate treatment. In this retrospective study, number isolated from clinical samples, their at genus/ level variations years Hacettepe University hospital which a center for patients risk infection were investigated. For purpose, laboratory...
Amaç: Mycobacterium tuberculosis kompleks’in çok ilaca dirençli suşlarının ortaya çıkması ve tüberkülozun yeniden önem kazanması, yeni tanı antibiyotik duyarlılık test yöntemlerinin geliştirilmesini teşvik etmiştir. Biz de çalışmamızda bu amaçla son zamanlarda geliştirilmiş bir yöntemi olan GeneXpert MTB/RIF testini, klinik örneklerden M. kompleksin tanımlanması rifampisin direncinin saptanmasında değerlendirdik. Gereç Yöntem: Çalışmamızda klasik tam otomatize kültür yöntemleri ile testi...
Apitherapy is a complementary medical technique that has an old history and applied in various diseases worldwide. Apitherapeutical applications are not treatment methods by themself, but theycan be substantial parts of multidisciplinary approaches. One them, bee venom therapy, currently-applied method Bee (BV) includes several substances such as peptides, phospholipids, bioactive amines, amino acids, sugars, pheromones, enzymes minerals.Studies on whole BV its singular components indicated...
Özgün Araştırma
Fungi are common contaminants of cheeses that provide suitable conditions for their growth. Although they added during the cheesemaking process as starter cultures, might also be from cheese ripening or storage environments. This study aimed to investigate diversity fungal microbiota and screen azole resistance Aspergillus flavus isolated these samples. A hundred samples (20 aged kashar, 20 fresh 25 white pickled, curd cheese, 10 cream cheese) were collected different vendors in bazaars...
Invazif fungal enfeksiyonlarda (IFE) erken tanı ve tedavi prognoz için çok kritiktir.Antimikrobiyal duyarlılık testleri, genel olarak seçenekleri klinik açısından önemli bir role sahiptir.
Objective: The prevalence of chronic hepatitis C worldwide is defined in three categories: low (<2.5%),medium (2.5-10%) and high (>10%) while the it seen between 0.5-1.9% Turkey.This study aims to identify most appropriate signal cut-off (S/Co) value observe viremia decrease number unnecessary virus-ribonucleic acid (HCV-RNA) analyzes due false positive anti-HCV results.Methods: A retrospective analysis was performed regarding relationship HCV-RNA results January 2019-September 2021.Adult...
Cystic fibrosis is an autosomal recessive disease with a defect in mucociliary activity that characterized by recurrent pulmonary infections. Bacterial agents frequently implicated airway colonization are Haemophilus influenzae, Staphylococcus spp., and Pseudomonas spp. Fungal isolation from sputum common adults. However, growth of fungal agent only culture patients cystic insufficient for the diagnosis diseases. There limited data about clinical significance cultures. The aim study was to...
Aim: The aim of this study is to investigate the prevalence Enterococcus species and evaluate susceptibilities antimicrobial agents in a state (secondary) hospital.
 Material Methods: A total 1676 enterococci strains (490 E.faecium, 1146 E.faecalis, 10 E.casseliflavus/E.gallinarum 30 other species) isolated from cultures obtained January 2017 December 2019 XXX Hospital were included. Blood incubated automated device (Render Biotech Co.Ltd., PRC). Other with conventional methods. Grown...
Objective: Staphylococci cause community-acquired and hospital-acquired infections, Staphylococcus aureus is one of leading agents. In the last decades methicillin-resistant S.aureus (MRSA), vancomycin-intermediate (VISA) vancomycin-resistant (VRSA) became as major concerns. Resistance to other antibiotics also another growing issue. The aim this study was investigate prevalence species evaluate susceptibilities antimicrobial agents in a state (tertiary) hospital.
 Methods: Clinical...
Clinical presentation of brucellosis is variable. Therefore, it must be confirmed with laboratory findings. Standard tube agglutination test (STAT) commonly used for diagnosis brucellosis. ELISA tests differentiate between IgM and IgG antibodies. However, there are evidences revealing that they do not have sufficient specificity. This study aimed to determine an optimal index value in the brucellosis.Brucella STAT IgM/IgG patients admitted hospital signs symptoms January 2017 December 2019...
ÖzLyme disease is a multisystemic and involvement of the nervous system called neuroborreliosis.Clinical manifestations peripheral neuroborreliosis include asymmetric polyradiculopathy, cranial nerve paralysis, multifocal mononeuropathies sensorymotor polyneuropathies.Guillain-Barré syndrome also known as acute inflammatory demyelinating polyneuropathy an immune-mediated neuropathy.Only limited number cases with Lyme presented Guillain-Barré symptoms are encountered in literature reviews,...
Mycobacterium abscessus kompleksin de dahil olduğu hızlı üreyen mikobakteriler, doğal ortamda bulunan ve özellikle bağışıklığı baskılanmış hastalarda fırsatçı patojen olabilen mikroorganizmalardır. Evre 4 nöroblastoma tanısı olan 10 yaşında bir kız hastada, M. tarafından oluşturulan kan dolaşımı enfeksiyonunu bildiriyoruz. Mikroorganizmanın kültürü şişesinden izole edilmesini müteakip; mikroorganizma, MALDI-TOF MS BD Phoenix otomatize tanımlama ilaç duyarlılık cihazı ile tanımlanmıştır....