J. Jacobs

ORCID: 0000-0003-2913-6297
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About
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Research Areas
  • Digital Radiography and Breast Imaging
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Smoking Behavior and Cessation
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Medical Imaging Techniques and Applications
  • AI in cancer detection
  • School Health and Nursing Education
  • Advanced X-ray and CT Imaging
  • Advanced Radiotherapy Techniques
  • Breast Cancer Treatment Studies
  • Cardiac Imaging and Diagnostics
  • Cancer Treatment and Pharmacology
  • Radiation Dose and Imaging
  • Asthma and respiratory diseases
  • Pluripotent Stem Cells Research
  • Health, psychology, and well-being
  • Chronic Disease Management Strategies
  • Nursing Diagnosis and Documentation
  • Cancer Immunotherapy and Biomarkers
  • Congenital heart defects research
  • Brain Metastases and Treatment
  • Pediatric health and respiratory diseases
  • Ear and Head Tumors
  • Peptidase Inhibition and Analysis
  • Reconstructive Facial Surgery Techniques

KU Leuven
2009-2025

Universitair Ziekenhuis Leuven
1989-2025

A.T. Still University
2024

Mayo Clinic in Arizona
2023

Jacobs (United States)
2023

Mayo Clinic
2023

Radboud University Medical Center
2004-2013

Radboud University Nijmegen
2004-2013

Sunnybrook Research Institute
2011

University of Freiburg
2010

In rare cases, immune checkpoint inhibitors (ICIs) cause immune-mediated myocarditis. However, true incidence of other major adverse cardiovascular events (MACEs) after ICI treatment remains unknown, mainly because late occurring side effects are rarely reported in prospective clinical trials. The aims this study were (1) to identify and risk factors MACE a real-life ICI-treated cancer cohort (2) compare rates with patients who not treated ICIs population controls.In total, 672 included....

10.1200/jco.21.01808 article EN Journal of Clinical Oncology 2022-06-30

Abstract Aims Cardiotoxicity is a serious side effect of anthracycline treatment, most commonly manifesting as reduction in left ventricular ejection fraction (EF). Early recognition and treatment have been advocated, but robust, convenient, cost-effective alternatives to cardiac imaging are missing. Recent developments artificial intelligence (AI) techniques applied electrocardiograms (ECGs) may fill this gap, no study so far has demonstrated its merit for the detection an abnormal EF after...

10.1093/eurjpc/zwad348 article EN European Journal of Preventive Cardiology 2023-11-07

Background Treatment for breast cancer (BC) frequently involves radiotherapy. Guidelines recommend screening cardiac adverse events starting 10 years after The rationale this interval is unclear. Methods and Results We aimed to study cardiovascular event rates in the first decade following curative radiotherapy BC. compared mortality with an age‐ risk factor‐matched control population. included 1095 patients BC (mean age 56±12 years). Two hundred eighteen (19.9%) women died. Cancer caused...

10.1161/jaha.122.027855 article EN cc-by-nc-nd Journal of the American Heart Association 2023-04-07

A Gram-positive, irregular rod-shaped, non-motile, yellow-pigmented bacterium, strain JG 31(T), was isolated in the course of identifying chromium-resistant soil bacteria. 16S rRNA gene sequence analysis bacterium indicated its phylogenetic position within genus Leucobacter. Binary alignments with 11 species recognized at time writing revealed similarities more than 97 % Leucobacter alluvii (GenBank accession no: AM072820; 99.4 %), iarius (AM040493; 98.2 aridicollis (AJ781047; 97.8 komagatae...

10.1099/ijs.0.022780-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2010-05-29

The present study reports on the biochemical validation of self-reported smoking status patients with chronic obstructive pulmonary disease (COPD). objective is to establish proportion overestimation success rates.A cross-sectional smoking-status including 60 COPD who reported that they had stopped smoking. In analysis urine samples, a cut-off point 50 ng/mL cotinine was used.At time validation, 55 quit while five resumed Smoking biochemically confirmed for 43 (78%) and 12 (22%) were...

10.2147/ijgm.s15231 article EN cc-by-nc International Journal of General Medicine 2011-01-01

Objective. To investigate the effect of a primary care model for COPD on process and patient outcome. Design. Controlled study with delayed intervention in control group. Setting. The GP delegates tasks to support service (CSS) practice nurse. CSS offers logistic through register recall system annual history-taking lung function measurement. It also forms link chest physician diagnostic therapeutic advice. nurse's most important are education counselling. Subjects. A total 44 practices (n...

10.1080/02813430701573943 article EN Scandinavian Journal of Primary Health Care 2007-01-01

Journal Article Image quality measurements and metrics in full field digital mammography: an overview Get access H. Bosmans, Bosmans Department of Radiology, University Hospitals Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium *Corresponding author: hilde.bosmans@uz.kuleuven.ac.be Search for other works by this author on: Oxford Academic PubMed Google Scholar A.-K. Carton, Carton F. Rogge, Rogge Zanca, Zanca J. Jacobs, Jacobs C. Van Ongeval, Ongeval K. Nijs, Nijs A. Steen, Steen G....

10.1093/rpd/nci711 article EN Radiation Protection Dosimetry 2005-12-01

Digital breast tomosynthesis is a new three-dimensional (3D) breast-imaging modality that produces images of cross-sectional planes parallel to the detector plane from limited number X-ray projections over angular range. Several technical and clinical parameters have not yet been completely optimised. Some open questions could be addressed experimentally; other parameter settings cannot easily realised in practice associated optimisation process requires therefore theoretical approach....

10.1093/rpd/ncq084 article EN Radiation Protection Dosimetry 2010-03-05

For the dose study, a semi-automated method of data collection is used in this study. The participating centres were asked to fill out spreadsheet with all necessary and return it. direct digital (DR) systems, relevant available DICOM header used. All automatically added database processed. calculate mean glandular for every image different thicknesses polymethyl methacrylate phantoms using conversion factors. Second-degree polynomials fitted patient reference curve was constructed range...

10.1093/rpd/ncn152 article EN Radiation Protection Dosimetry 2008-02-18

To compare two methods for assessment of image-processing algorithms in digital mammography: free-response receiver operating characteristic (FROC) the specific task microcalcification detection and visual grading analysis (VGA).The FROC study was conducted prior to VGA reported here. 200 raw data files low breast density (Breast Imaging-Reporting Data System I-II) mammograms (Novation DR, Siemens, Germany)-100 which abnormal-were processed by four algorithms: Raffaello (IMS, Bologna,...

10.1259/bjr/22608279 article EN British Journal of Radiology 2012-07-29

Smoking influences oral health in several ways (such as the occurrence of periodontitis, teeth discolouration and cancer); therefore, smoking behaviour should be addressed dental care. Dentists can play a role primary secondary prevention tobacco dependence. They see their patients repeatedly over time. This study investigates whether complaints seized an opportunity to start cessation counselling.A structured patient questionnaire sample 1101 smokers (52.1% women, mean age 40.4 years)...

10.1111/j.1600-0528.2010.00553.x article EN Community Dentistry And Oral Epidemiology 2010-06-11

Purpose To investigate the dosimetric impact of breathing motion on robustly optimized proton therapy treatment plans for left-sided breast cancer patients with an indication locoregional irradiation.Materials and methods Clinical Target Volumes (CTVs) (left-sided breast, level 1 to 4 axillary lymph nodes, interpectoral internal mammary node regions) organs at risk were delineated D-CTs ten female patients. After planning a prescribed dose 40.05 Gy(RBE) in 15 fractions time-averaged CT, was...

10.1080/0284186x.2020.1825800 article EN cc-by-nc-nd Acta Oncologica 2020-12-03
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