- Neurological Disorders and Treatments
- Musculoskeletal pain and rehabilitation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pain Mechanisms and Treatments
- Sleep and related disorders
- Rheumatoid Arthritis Research and Therapies
- Spine and Intervertebral Disc Pathology
- Vestibular and auditory disorders
- Migraine and Headache Studies
- Healthcare Systems and Public Health
- Heart Rate Variability and Autonomic Control
- Sleep and Wakefulness Research
- Multiple Sclerosis Research Studies
- Human Health and Disease
- Osteoarthritis Treatment and Mechanisms
- Peripheral Neuropathies and Disorders
- Parkinson's Disease Mechanisms and Treatments
- Myofascial pain diagnosis and treatment
- Neurological Disease Mechanisms and Treatments
- Dementia and Cognitive Impairment Research
- Neurological disorders and treatments
- Pharmacological Effects of Natural Compounds
- Stroke Rehabilitation and Recovery
- Botulinum Toxin and Related Neurological Disorders
- Spondyloarthritis Studies and Treatments
Kazan State Medical University
2014-2023
Consultative and Diagnostic Center
2023
Izhevsk State Medical Academy
2023
The First Republican Clinical Hospital of the Ministry of Health of the Udmurt Republic
2023
Ministry of Health of the Russian Federation
2018-2022
KLE Society Hospital
2018
Sir Ganga Ram Hospital
2018
Research Medical Center
2017
In-Q-Tel
2013
ABSTRACT Motor complications in Parkinson's disease (PD) are associated with long‐term oral levodopa treatment and linked to pulsatile dopaminergic stimulation. l ‐dopa‐carbidopa intestinal gel (LCIG) is delivered continuously by percutaneous endoscopic gastrojejunostomy tube (PEG‐J), which reduces l‐ dopa‐plasma–level fluctuations can translate reduced motor complications. We present final results of the largest international, prospective, 54‐week, open‐label LCIG study. PD patients severe...
Examination of a patient with chronic low back pain (LBP) is aimed at eliminating its specific cause and assessing the social psychological factors pain. The diagnosis nonspecific (musculoskeletal) LBP based on exclusion pain, discogenic radiculopathy, lumbar stenosis. It advisable to identify possible sources: pathology intervertebral disc pathology, facet joints, sacroiliac joint myofascial syndrome. An integrated multidisciplinary approach (a high level evidence), including therapeutic...
Objective. To present the recommendations of expert council Russian Society for Study Pain on “Dorsumio” drug in treatment chronic nonspecific back pain (CNBP). Key points. Currently, CNBP is leading disease associated with disability worldwide. Patients often experience concomitant depressive and anxiety symptoms complicating course therapy, as well worsening quality life working capacity. Various problems care include not only impact pathogenesis pain, but also depression, anxiety,...
This consensus was developed to establish the terms, basic concepts, and approaches of non-drug treatment chronic insomnia — cognitive-behavioral therapy (CBT-I). The text captures view professional community that both clinical psychologists psychotherapists, as well doctors various specializations with experience in diagnosis sleep disorders, can use CBT-I knowledge skills listed relevant section. Indications contraindications are also listed, a brief description behavioral cognitive...
When examining a patient with lumbosacral pain, it is necessary to rule out the specific cause of disease. The diagnosis discogenic radiculopathy (DLSR) based on clinical examination; magnetic resonance imaging (MRI) informative value in excluding other causes and evaluating disk herniation. If signs cauda equina spinal cord compression are absent, no epidural glucocorticoid injection or urgent surgical treatment scheduled, there reason for early (within first 4 weeks) MRI.It recommended...
In recent decades, there has been an increase in the prevalence and medical social burden of osteoarthritis (OA) nonspecific back pain all countries world. The First Multidisciplinary Bilateral Russia-Uzbekistan Expert Council presented innovations prognosing, personalized prevention adjuvant therapy degenerative-dystrophic diseases joints spine, evidence base for effectiveness safety use drugs that modify course OA (Disease-modifying drugs, DMOADs): chondroitin sulfate, glucosamine...
The first reports of narcolepsy with cataplexy in Russia were made by Mankovsky (The pathogenesis (the case epidemic encephalitis cataplexy) published the Sovremennaya psihonevrologia) 1925. largest series patients (n = 110) was reported A. Vein (doctoral thesis: Hypersomnia Syndrome) 1964. However, until today, remained relatively unknown Russia. aim this study is to report clinical and polysomnography (PSG)/multiple sleep latency test (MSLT) results Russian population compare them European...
Diagnosis and treatment of early forms cognitive impairment: possibilities influencing neuronal energy metabolism. Resolution the Council Experts.Диагностика и лечение ранних форм когнитивных нарушений. Возможности воздействия на энергетический метаболизм нейронов. Резолюция Совета экспертов.
One of the key mediator systems involved in pathogenesis migraine is serotonergic system, which led to development and introduction serotonin 5-HT1 receptor agonists (triptans) into clinical practice as most important means preventing attacks. Serotonin have a high selectivity for 5-HT1B 5-HT1D subtypes, ensures their effect on attack development. Objective : evaluate efficacy standard dose Relonova relief four moderate severe attacks outpatients reallife practice, including assessment rate...
To assess the role of music therapy in recovery motor, speech and autonomic functions patients with ischemic stroke (II).Forty-five II middle cerebral artery were examined. The randomized into three groups (main, comparison control) 15 individuals each. With first second on 3rd, 5th, 7th 9th days rehabilitation period special set exercises without that respectively was fulfilled. third group received a basic physical (a control group).The control. Dynamics patients' state estimated by NIHSS,...
Alzheimer's disease (AD) is a devastating and progressive form of dementia that typically associated with build-up amyloid-β plaques hyperphosphorylated misfolded tau protein in the brain. Presently, there no single test confirms AD; therefore, definitive diagnosis only made after comprehensive medical evaluation, which includes history, cognitive tests, neurological examination and/or brain imaging. Additionally, protracted prodromal phase makes selection control subjects for clinical...
Despite the variety of treatment options, pain syndromes are widespread in population. Adjuvant methods, particular vitamins and vitamin combinations, widely used, along with nonsteroidal anti-inflammatory drugs, myorelaxants anticonvulsants, by physicians different specialties. In recent years, new drugs containing pyrimidine nucleotides (uridine monophosphate) were brought to market. The paper describes analgesic effects uridine monophosphate choline, possibilities their simultaneous use...
Остеоартрит суставов позвоночника как причина хронической боли в нижней части спины
To study the impact of combination therapy with mexidol and cerebrolysin on clinical status patients chronic cerebral ischemia (CCI), II stage, in ambulatory conditions.The included 36 CCI, stage. In addition to basic therapy, received two courses mexidol/cerebrolysin during 6 weeks 3 month-interval between courses. The dynamics subjective complaints objective signs was assessed after each course. content 13 chemical elements hair determined by atomic-emission method treatment.Based results...
The article presents the results of first observational study in Russian Federation on efficacy and safety high doses uridine monophosphate (150 mg) combination with choline (the supplement neurouridine) treatment patients nonspecific low back pain.The Visual Analogue scale (VAS), painDETECT questionnaire (PD-Q), Roland-Morris Low Back Pain Disability Questionnaire, Hospital Anxiety Depression Scale (HADS) Pittsburgh Sleep Quality Index were used to assess neurouridin 50 lower pain.A...
Реферат.В статье приведен обзор литературы, касающийся особенностей течения, клинических проявлений и диагностики хронической формы клещевого энцефалита.Подробно изложены версии развития патологического процесса рассмотрены такие варианты патогенеза, как длительная, немая персистенция вируса в организме вследствие поражения клеток глии; затронуты вопросы сохранения человека вирусного генома пути его «активации».В приведена классификация инфекции с обзором вариантов течения...
To perform a differential analysis of the efficacy combination therapy by drugs with different modalities (mexidol, aescusan, halidorum) in outpatients chronic cerebral ischemia (CCI), stages I- III.A study included 50 patients CCI atherosclerotic, hypertensive and mixed genesis (stage I - 20 patients, stage II 20, III 10 patients). In addition to somatic therapy, received three courses mexidol, halidorum aescusan during 6 weeks 3 month interval between courses. The changes subjective...