Guanfeng Chen

ORCID: 0000-0003-3017-731X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Cell Adhesion Molecules Research
  • Advanced MRI Techniques and Applications
  • Peroxisome Proliferator-Activated Receptors
  • Cancer, Lipids, and Metabolism
  • Sleep and Wakefulness Research
  • Neutropenia and Cancer Infections
  • Inflammatory Biomarkers in Disease Prognosis
  • Immune Response and Inflammation
  • Cancer, Hypoxia, and Metabolism
  • Protease and Inhibitor Mechanisms
  • Sleep and related disorders
  • MRI in cancer diagnosis
  • S100 Proteins and Annexins
  • Glioma Diagnosis and Treatment

Xuzhou Medical College
2024-2025

Fujian Medical University
2021-2022

Background: Gynecological malignancies, such as endometrial cancer (EC) and uterine are prevalent. Increased Acyl-CoA synthetase long-chain family member 1 (ACSL1) activity may contribute to aberrant lipid metabolism, which is a potential factor that contributes the pathogenesis of cancer. This study aimed elucidate molecular mechanisms by ACSL1 involved in metabolism cancer, providing valuable insights for targeted therapeutic strategies. Methods: Xenograft mouse models were used assess...

10.31083/j.fbl2902066 article EN cc-by Frontiers in Bioscience-Landmark 2024-02-06

Epithelial ovarian cancer (EOC) is a highly aggressive malignancy with poor prognosis due to late-stage diagnosis and the lack of reliable biomarkers for early detection. Exosomes, small vesicles involved in intercellular communication, play critical role progression by promoting migration, proliferation, metastasis. This study investigates exosomal proteins EOC cell migration identifies potential biomarkers. Exosomes are isolated from ascites fluid patients (C-Exos) benign disease (B-Exos),...

10.3724/abbs.2025024 article EN cc-by-nc-nd Acta Biochimica et Biophysica Sinica 2025-02-19

Background.The T lymphocyte subset levels are an indicator used to evaluate the immune status of body.In recent years, many studies have investigated correlation between and postoperative infection. Objectives.To investigate incidence infection after liver cancer interventional therapy its influence on toll-like receptors (TLRs). Materials methods.A total 325 patients with primary receiving were divided into group (n = 37) a non-infection 288).The site distribution pathogenic bacteria in...

10.17219/acem/141499 article EN cc-by Advances in Clinical and Experimental Medicine 2021-11-04

Based on multimodal functional magnetic resonance imaging technology, explore the changes of local brain function in whole range patients with primary insomnia at rest, and conduct correlation analysis to relationship between this locality clinical features. Provide further evidence for exploration neural mechanism insomnia. Using imaging, self-rating anxiety scale, depression scale assess status factor trait STAI (88 cases) normal sleepers (82 cases). Factors total scores, depressive mental...

10.1166/jmihi.2021.3712 article EN Journal of Medical Imaging and Health Informatics 2021-05-21
Coming Soon ...