A5007587098- Leprosy Research and Treatment
- Nonmelanoma Skin Cancer Studies
- Cutaneous Melanoma Detection and Management
- Drug-Induced Adverse Reactions
- Mycobacterium research and diagnosis
- Cutaneous lymphoproliferative disorders research
- Contact Dermatitis and Allergies
- Nail Diseases and Treatments
- Infectious Diseases and Tuberculosis
- Urticaria and Related Conditions
- Eosinophilic Disorders and Syndromes
- Autoimmune and Inflammatory Disorders
- Dermatological and COVID-19 studies
- Fungal Infections and Studies
- Psoriasis: Treatment and Pathogenesis
- Ear and Head Tumors
- Immune Cell Function and Interaction
- Sarcoidosis and Beryllium Toxicity Research
- COVID-19 and healthcare impacts
- Dermatologic Treatments and Research
- Genetic and rare skin diseases.
- Histiocytic Disorders and Treatments
- Vascular Tumors and Angiosarcomas
- Ocular Diseases and Behçet’s Syndrome
- Body Contouring and Surgery
Universidade de São Paulo
2012-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2014-2024
Universidade Federal de São Paulo
2018
Hospital Universitário da Universidade de São Paulo
2016
Ministério da Saúde
2016
Centro Universitário das Faculdades Metropolitanas Unidas
2015
Drug reaction with eosinophilia and systemic symptoms (DRESS) [also called drug-induced hypersensitivity syndrome (DIHS)] includes severe reactions to drugs that need be promptly recognized by physicians.To explore heterogeneity in the clinical presentation of DRESS/DIHS at a large academic hospital Latin America, using criteria defined European Registry Severe Cutaneous Adverse Reactions (RegiSCAR) scoring system.A retrospective medical record review 60 patients diagnostic suspicion...
Leprosy is frequently complicated by the appearance of reactions that are difficult to treat and main cause sequelae. We speculated disturbances in regulatory T-cells (Tregs) could play a role leprosy reactions. determined frequency circulating Tregs patients with type 1 reaction (T1R) 2 (T2R). The situ interleukin (IL)-17, IL-6, transforming growth factor beta (TGF)-β-expressing cells was also determined. T2R showed markedly lower number than T1R controls. This decrease paralleled increased...
Leprosy is a chronic granulomatous infection caused by Mycobacterium leprae. It polymorphic disease with wide range of cutaneous and neural manifestations. Ulcer not common feature in leprosy patients, except during reactional states, Lucio's phenomenon (LP), or secondary to neuropathies.We report eight patients multibacillary who presented specific skin ulcers as part their main manifestation. Ulcers were mostly present on lower limbs (eight patients), followed the upper (three abdomen (one...
Histoid leprosy (HL) is a rare form of lepromatous leprosy, characterized by hyperchromic indurated nodules above normal skin. Its main histopathological aspect spindle cells. Because it may simulate other aspects, such as dermatofibroma and neurofibroma, histoid poses itself diagnostic challenge.This retrospective study with all patients having been selected from the clinic Hospital das Clínicas da Universidade de São Paulo 2006 to 2016.There were 12 in this study, eight group four group....
Brazilian Unified Health System presents a long waiting period for dermatology appointment, varying from 34 to 239 days.
Abstract We present a 16‐year‐old boy with multiple, well‐circumscribed, atrophic, light‐brown patches on his neck, chest, and back. The authors believe that it represents an unusual presentation of atrophoderma Pasini Pierini suggest the designation “generalized lenticular APP .”
A 70-year-old male presenting a 3-month history of genital painless erythematous nodules in the balanopreputial sulcus was referred to our service. Histopathological exam presented chronic dermatitis with epithelioid granulomas and Grocott staining revealed numerous fungal structures suggestive morphology Histoplasma sp. Cultures evidenced capsulatum var. capsulatum. Treatment oral itraconazole led complete remission lesions.
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare conditions characterized by necrosis, mostly caused drugs. Despite the rarity of these conditions, morbidity mortality high (even in previously healthy patients), they may be associated with permanent sequelae.A retrospective study conducted at a quaternary hospital Brazil period 10 years.The sample was composed 41 patients SJS, SJS/TEN, TEN confirmed skin biopsy. Antibiotics anticonvulsants were most frequently...
Objectives: This work aims to determinate the main severe adverse reactions multidrug therapy (MDT), as well characteristics of patients who had them and period when they were more prevalent. Results: Of 158 undergoing treatment for leprosy in 2012–2017, 22 (13.9%) using substitutive presented criteria enter this study. Adverse frequent women (59.1%), above 45 years age during second month treatment. Dapsone was most frequently implied drug (86.4%), hemolytic anemia reaction (72.7%)....
Leprosy is a contagious and chronic systemic granulomatous disease caused by the bacillus Mycobacterium leprae. To our knowledge, no case of leprosy in childhood-onset lupus erythematosus (c-SLE) patient has been reported. For period 31 years, 312 c-SLE patients were followed at Pediatric Rheumatology Unit University Hospital. One them (0.3%) had tuberculoid skin lesions during course here A 10-year-old boy from Northwest Brazil was diagnosed with based on malar rash, photosensitivity, oral...
The most commonly seen nail change in sarcoidosis, often associated with chronic systemic disease, is onychodystrophy. Imaging of hands, feet and chest paramount importance when sarcoidosis suspected, for evaluation bone cysts pulmonary involvement, respectively. We report 2 cases that developed involvement - one the other without any evidence which very rare.
Erythroderma is characterized by erythema and scaling affecting more than 90% of the body surface area. Inflammatory, neoplastic and, rarely, infectious diseases may culminate with erythroderma. Diagnosis underlying disorder therefore crucial to institute appropriate therapy. Leprosy a chronic disease that endemic in Brazil. Here we present an unusual case leprosy reversal reaction causing erythroderma, discuss immunological mechanisms which could contribute generalized skin inflammation. We...
Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) a member the herpes family with tropism for endothelial cells and it has been proven to induce neoplasms, such as Kaposi's sarcoma. The role HHV-8 in pathogenesis angiosarcoma not well defined.To investigate relationship between presence angiosarcoma.In this study, team investigated HHV-8, determined by polymerase chain reaction, angiosarcoma, using samples from patients epidemic sarcoma...
Abstract Background Dermoscopy is a non‐invasive, cost‐effective tool useful in the assessment of pigmented lesions. The aim this study was to analyze dermoscopic features excised melanomas tertiary hospital Brazil and influence Breslow thickness on observed. Methods An observational, cross‐sectional which images 43 were evaluated. patients divided into three groups: situ , thin invasive melanoma (Breslow <1 mm), thick ≥1 mm). Results We studied 33 with melanomas. Twenty‐one (48.8%) 16...