A5079514639- Evolution and Genetic Dynamics
- Evolutionary Game Theory and Cooperation
- Plant and animal studies
- Genetic diversity and population structure
- Mathematical and Theoretical Epidemiology and Ecology Models
- Chromosomal and Genetic Variations
- Ecology and Vegetation Dynamics Studies
- Animal Behavior and Reproduction
- Genomics and Phylogenetic Studies
- CRISPR and Genetic Engineering
- Species Distribution and Climate Change
- Plant Reproductive Biology
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- COVID-19 epidemiological studies
- Plant Parasitism and Resistance
- Evolution and Paleontology Studies
- Genetic Mapping and Diversity in Plants and Animals
- Fungal and yeast genetics research
- Plant Virus Research Studies
- Animal Ecology and Behavior Studies
- SARS-CoV-2 and COVID-19 Research
- Insect and Arachnid Ecology and Behavior
- Marine Bivalve and Aquaculture Studies
- Insect symbiosis and bacterial influences
- Gene Regulatory Network Analysis
University of British Columbia
2016-2025
Okanagan University College
2019-2024
University of British Columbia Hospital
2021
Oxford University Press (United Kingdom)
2021
American Institute of Biological Sciences
2021
Carleton University
2020
Hudson Institute
2019
John Wiley & Sons (United States)
2019
British Academy
2015
Epistem (United Kingdom)
2015
Determining whether speciation and extinction rates depend on the state of a particular character has been long-standing interest to evolutionary biologists. To assess effect diversification using likelihood methods requires that we be able calculate probability group extant species would have evolved as observed, given model character's effect. Here describe how this for phylogenetic tree two-state (binary) under simple evolution (the "BiSSE" model, binary-state extinction). The involves...
Species traits may influence rates of speciation and extinction, affecting both the patterns diversification among lineages distribution species. Existing likelihood approaches for detecting differential require complete phylogenies; that is, every extant species must be present in a well-resolved phylogeny. We developed 2 methods can used to infer effect trait on extinction without phylogenetic information, generalizing recent binary-state method. Our where phylogeny reasonably assumed...
The doubling of genomes does not cause increased plant speciation unless the progenitor lineages are highly fit.
We inferred phylogenetic trees from individual genes and random samples of nucleotides the mitochondrial genomes 10 vertebrates compared results to those obtained by analyzing whole genomes. Individual are poor in that they infrequently lead whole-genome tree. A large number nucleotide sites is needed exactly determine relatively small sites, however, often a tree close found blocks contiguous were less likely than composed drawn individually throughout genome. Samples not representative...
Scientists perform experiments and gather data to gain evidence for or against various hypotheses about how the world works. This sounds straightforward, but exactly we use this make quantitative statements requires a bit more care. In fact, there are two related, philosophically distinct, approaches scientific inference. To some extent these parallel frequency interpretation subjective of probability. “Classical” statistical analysis is most closely allied with interpretation, whereas...
The vast majority of eukaryotic organisms reproduce sexually, yet the nature sexual system and mechanism sex determination often vary remarkably, even among closely related species. Some species animals plants change across their lifespan, some contain hermaphrodites as well males females, determine with highly differentiated chromosomes, while others according to environment. Testing evolutionary hypotheses regarding causes consequences this diversity requires interspecific data placed in a...
There is a long tradition in population genetics of exploring the maintenance variation under migration-selection balance using deterministic models that assume infinite size. With finite size, stochastic dynamics can greatly reduce potential for polymorphism, but this has yet to be explored detail. Here, classical two-patch are extended predict: (1) probability locally beneficial mutation rising frequency patch where it favored and (2) critical threshold migration rate above which...
Evolutionary biologists have often assumed that ecological generalism comes at the expense of less intense exploitation specific resources and this trade-off will promote evolution ecologically specialized daughter species. Using a phylogenetic comparative approach with butterflies as model system, we test hypotheses incorporate changes in niche breadth location into explanations taxonomic diversification insect herbivores. Specifically, compare oscillation hypothesis, where speciation is...
The rate of adaptive evolution a population ultimately depends on the incorporation beneficial mutations. Even mutations may, however, be lost from since mutant individuals by chance, fail to reproduce. In this paper, we calculate probability fixation that occur in populations changing size. We examine number demographic models, including whose size changes once, experiencing exponential growth or decline, one is logistic and fluctuates results are based branching process model but shown...
One of the oldest hypotheses for advantage recombination is that allows beneficial mutations arise in different individuals to be placed together on same chromosome. Unless occurs, one alleles doomed extinction, slowing rate at which adaptive are incorporated within a population. We model effects modifier fixation probability when segregating other loci. find increase do mutants and subsequently hitchhike along as rise frequency. The strength selection favoring increases proportional...
The Red Queen hypothesis posits that sex has evolved in response to the shifting adaptive landscape generated by evolution of interacting species. Previous studies supporting have considered a narrow region parameter space and only subset ecological genetic interactions. Here, we develop population genetics model circumscribes broad array interactions among species derive first general analytical conditions for impact on sex. Our results show typically select against We conclude that,...
Abstract The reasons that sex and recombination are so widespread remain elusive. One popular hypothesis is promote adaptation to a changing environment. strongest evidence increased may evolve because promotes comes from artificially selected populations. Recombination rates have been found increase as correlated response selection on traits unrelated in several artificial experiments comparison of domesticated nondomesticated mammals. There are, however, alternative explanations for the...