A5077415457- Bacillus and Francisella bacterial research
- Yersinia bacterium, plague, ectoparasites research
- Zoonotic diseases and public health
- Vibrio bacteria research studies
- Healthcare Systems and Public Health
- Animal Ecology and Behavior Studies
- Metabolomics and Mass Spectrometry Studies
- Biomedical and Engineering Education
- COVID-19 epidemiological studies
- Supply Chain Resilience and Risk Management
- Education, Law, and Society
- Medical Research and Treatments
- Escherichia coli research studies
- Rabies epidemiology and control
- Arctic and Russian Policy Studies
- Bacteriophages and microbial interactions
- Technology and Human Factors in Education and Health
- Brucella: diagnosis, epidemiology, treatment
- Clostridium difficile and Clostridium perfringens research
Russian Scientific Research Institute Microbe
2008-2022
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2020
Rostov-on-Don Anti-plague Institute Rospotrebnadzor
2020
Objective of the investigation was to assess epidemiological and epizootiological conditions in natural plague foci Russian Federation, neighboring states foreign countries 2019. Negative effect current climate warming on state parasitic systems with circulation microbe main subspecies, medieval biovar, phylogenetic branch 2.MED1 is emphasized. In 2019, local epizooties were registered territory two (Gorno-Altai high-mountain Tuva mountain) out 11 Federation. The total area epizooty covered...
Up to date there is a narrow and broad interpretation of the term biological safety (BS) world over. In sense it defined as availability international regulations applied diagnostic, manufacturing, or experimental works with pathogenic agents (PBA) in accordance specified levels hazard BS. broader context has no national, conceptual, terminological defying basis. Therewith, establishment this framework become core issue study. Investigations have revealed that BS should conceptually cover...
Consequent of investigation concerned with biological safety (BS) framework development in its broad interpretation, reflected the Russian Federation State Acts, identified have been conceptual entity parameters up-to-date interpretation BS, which formed a part developed by authors system for surveillance (prophylaxis, localization, indication, identification, and diagnostics) control localization , response/ elimination) over emergency situations (ES) (sanitary-epidemiological) character....
Live plague vaccines have saved thousands of human lives in the 20th century and continued to be used Russia other countries former Soviet Union for prophylaxis plague. A live attenuated Y. pestis EV strain line NIIEG is routine annual vaccination workers, as well people from groups at risk. This can offer immunity against both bubonic pneumonic However, serologic markers response with are poorly investigated. It not clear whether antigens, addition established capsular antigen F1...
A set of risk assessment methods was used for substantiation safe functioning mobile laboratories (ML) specialized anti-epidemic teams (SAET). The utilized were borrowed from diverse spheres activity and recommended evaluation biological hazard associated with work pathogenic agents. obtained data represent the basis biorisk management in SAET` ML functioning.
Human leukocytes containing less than 2C DNA per cell (damaged or dead cells) were detected and quantified by flow cytometry DNA-specific staining with ethidium bromide mithramycin in whole blood infected Staphylococcus aureus Yersinia pestis. Addition of live S. to the (100 microbe cells one leukocyte) resulted rapid degradation leukocyte within 3 6 hours incubation at 37 degree(s)C. However, only about 50 percent damaged intact genetic apparatus could be found for a period up 24 hours. The...
Carried out is a range of investigations aimed at the improvement anti-epidemic procedures for works with infectious disease agents (herein biological safety provision) in mobile laboratories specialized teams (SAET). Evaluation operational experience stationary and field laboratories, as well comparative analysis national requirements pathogenic WHO international regulations sphere provision has made it possible to outline common all types microbiological principles biosafety provision....
At present, in compliance with sanitary and epidemiologic regulations force, equipping of microbiological laboratory modern engineering technical systems equipment is considered to be the important condition ensuring adherence biological safety requirements. The abovementioned equipment, together rules techniques safe work pathogenic microorganisms, should provide set measures for personnel. Biological cabinets second third classes serve as additional protection means. Considered are...
Population approach to determination of the borders and number natural plague foci implies specialists’ acceptance concept that existence a focus is always provided by single population main carrier. Motivation for our discussion such an was data long-term study Hissar (Tadzhikistan). The area only 300 km2 its functioning maintained single, relatively small Microtus carruthersi (Thomas, 1909) – carrier plague. mountain range territories adjacent have been surveyed more than 20 years,...
Objective of the study was to select criteria and methodological approaches reclassify avirulent strains plague agent from pathogenicity (hazard) group I into III. Materials methods . We have reviewed domestic foreign normative, documents, scientific publications in field laboratory diagnostics biosafety provision while working with pathogenic biological agents. Results discussion. A complex for reclassification Y. pestis hazard III has been substantiated; their assessment identified....
The aim was to present the experience of using mobile laboratory for monitoring and diagnostics (MLMD) during epizootiological northern provinces Vietnam. MLMD transferred by Federal Service Surveillance in Sphere Consumers Rights Protection Human Welfare Socialist Republic Vietnam as part implementation cooperation programs on combating infectious diseases. use made it possible obtain new information circulation pathogens natural-focal diseases territory It also provided necessary...
Presented is the algorithm of assessment level professional qualification personnel authorized for work with pathogenic biological agents I-II groups, developed first time. Determined are essence, requirements organization and order indices that predict presence occupational knowledge skills necessary safe, high-quality effective execution duties.
Analyzed is the performance of works with strains fixed rabies virus under conditions anti-rabies immunoglobulin manufacturing. Evaluated effectiveness established system for provision biological safety, which has allowed safe manufacturing within period 12 years.
The results of the second phase experiments are presented in paper, where β-propiolactone was used to decontaminate materials from Yersinia pestis. Both slurries and suspensions internal organs were decontaminated Y. pestis 231 with 0.1 % concentrations preparation after 18 24 hours' exposition refrigerator, as well at 37 °C for long 6 hours or more. Optimal schedules immunologic examination offered prepare samples taken combined foci plague arboviral infections.
Within the frames of an analytical review, modern approaches are described whose development is considered to be very important in order rationally operate secure working procedures at facilities medical and biological profile. Peculiarities formulating methods assess hazards analyzed together with ways their objectivization. The place role safety as a scientific trend discussed relation problem availability practical application "risk theory" elements aim making governing decisions based on...
For a reliable assessment of the presense immune layer to cholera agent, it is necessary determine level specific antibodies in human blood serum. To detect anticholera serological methods are used, aimed identify agglutinating, vibriocidal and toxin neutralizing antibodies. At same time, stated have several drawbacks which can be eliminated when using biological microarrays Object work . Assessment agent individuals residing territory Republic Guinea, microchip. Materials 190 serum samples...