A5046725620- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Neurological Complications and Syndromes
- Organ Donation and Transplantation
- Dialysis and Renal Disease Management
- Renal and Vascular Pathologies
- Pharmacological Effects and Toxicity Studies
- Connective Tissue Growth Factor Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Blood Pressure and Hypertension Studies
- Pregnancy and Medication Impact
- Potassium and Related Disorders
- Peptidase Inhibition and Analysis
- dental development and anomalies
- Palliative Care and End-of-Life Issues
- Research on Leishmaniasis Studies
- Mental Health Treatment and Access
- Ethics in Clinical Research
- Methemoglobinemia and Tumor Lysis Syndrome
- Oral and gingival health research
- Nausea and vomiting management
- Lymphatic System and Diseases
- Pesticide Exposure and Toxicity
- Erythropoietin and Anemia Treatment
- Magnesium Alloys: Properties and Applications
Agostino Gemelli University Polyclinic
2014-2016
Hospital de Clínicas de Porto Alegre
2009-2015
Universidade Federal do Rio Grande do Sul
2009-2015
Università Cattolica del Sacro Cuore
2013-2015
Catholic University of America
2013
Aim of this study was to evaluate the association between attachment style, compliance, quality life and renal function in adult patients after kidney transplantation.A total 43 who received a transplant more than 3 months before were enrolled asked complete two Self-Report questionnaires: Attachment Style Questionnaire (ASQ-40) Short Form Health Survey (SF-36). Also compliance measured using appropriate questions.Linear regression analysis showed associations confidence relationships [beta...
Kidney injury molecule-1 (KIM-1) is expressed in tubular epithelial cells after and may have a role the development of renal graft fibrosis. In this study we evaluated molecular protein expressions KIM-1 dysfunctional allografts also mRNA expression urine as potential biomarkers Protein levels tissue urinary sediment 69 kidney transplant recipients that undertook for-cause biopsies were by immunohistochemistry real-time polymerase chain reaction. The histopathology was classified according...
Multiple organ failure syndrome and acute renal dysfunction share many of physiologic factors involved in their development. Recent studies correlate the susceptibility to critically ill patients with genetic inheritance. Many them consider ACE gene could be a possible candidate elucidate predisposition or risk factor. We aimed examine effects I/D -262A > T polymorphisms function severely southern Brazilians patients. A multi-organic worldwide known score, SOFA (sequential assessment), was...
Abstract We compared in kidney transplantation two immunosuppressive regimens: tacrolimus plus mycophenolate mofetil (MMF) ( TAC ) and everolimus low‐dose cyclosporine EVE ). Sixty consecutive patients received (30 patients) or as regimen; all subjects also induction with basiliximab corticosteroids. After three‐yr follow‐up, no difference was found patient graft survival PTS : TAC: 97% vs. 100%; GS: 93% 93%). The incidence of acute rejection higher the group but not statistically...
Intoxicações acidentais e intencionais constituem- se em fonte significativa de morbimortalidade. Em emergências ou UTIs, frequentemente o Nefrologista é chamado como consultor para auxiliar na indicação medidas aumento da depuração renal agentes tóxicos. Revisamos emprego diálise nas intoxicações agudas por medicamentos pesticidas, cujo suporte especializado toxicológico foi realizado telefone pelo Centro Informação Toxicológica do Rio Grande Sul (CIT-RS). Avaliamos a correlação entre...
Calcineurin inhibitors have been the mainstay of immunosuppression for last decades and nowadays still remain as relevant drugs in setting solid organ transplantation. Nevertheless, balance between excess with cyclosporine (leading to increased risk metabolic complications, nephrotoxicity or cancer), its insufficiency (with augmented rejection), is even so a challenge clinical practice. The aim this paper review pharmacokinetic pharmacodynamic evolution landmark drug. We also discuss what...
Background: There are not enough middle term data on the outcomes of CNIs and Everolimus (EVE) regimens in de novo renal transplantation (KTx). Methods: We report 3y a prospective study assessing CNI reduction vs Tacrolimus, 96 low to moderate immunological risk pts, who received basiliximab rabbit anti-thymocyte globulin at 50 mg/day for 4 days post KTx were then randomized 1:1:2 to: a) TAC+EVE, b) CsA+EVE, c) TAC+MMF. All pts steroid first 3m, was selectively withdrawn. Data with kidney...
Background The predictive value of preimplantation biopsies for long-term graft function is often limited by conflicting results. aim this study was to evaluate the influence time-zero biopsy histological scores on early and late function, survival patient survival, at different time points. Methods We retrospectively analyzed 284 a single center, in cohort recipients with grafts from live deceased donors (standard nonstandard), their impact posttransplant renal after mean follow-up 7 years...
Introduction: Aim was to design, test and validate a new predictive score index for 5-yr kidney graft survival. Methods: Pre-transplant risk factors pre-implantation biopsy data were evaluated in 601 renal transplants performed from 1997 2012. The points model included donor recipients the implantation (IBS). system generated by collected 323 pts tested 278 out of 601. Results: Considering groups, mean recipient age respectively 45±12 vs 46±12 (p=0.99), 52.5% 47.5% males (p=0.43), BMI 24.6...
Background: Kidney graft fibrosis is a major factor related to chronic loss of kidney function. Graft different factors including alloimmune mechanisms, drug toxicities and infections among others. Evaluation genes development may lead the useful biomarkers such process. In this study we evaluated molecular expression test hypothesis that, in patients with disease renal transplant, these molecules are fibrosis, presenting elevated mRNA transcripts levels. Patients methods: RNA was extracted...