A5022276572- Leptospirosis research and findings
- Veterinary medicine and infectious diseases
- Viral Infections and Vectors
- Orthopedic Infections and Treatments
- Bacterial Identification and Susceptibility Testing
Universiti Putra Malaysia
2018-2022
Leptospirosis is often misdiagnosed with several other tropical febrile illnesses in Malaysia due to similarities clinical manifestations. Although treatment regimens could be started based on judgments, early diagnosis has become paramount as a guide chemotherapeutic interventions. Confirmed laboratory through MAT or PCR time consuming and usually available only reference laboratories not practical healthcare settings. Rapid easy perform diagnostic tests are widely used these settings the...
Background Leptospirosis is a zoonotic disease caused by bacteria of the genus Leptospira that affects both humans and animals worldwide. Early detection pathogen in crucial for early intervention control progression to severe state. It also vitally important be able detect presence carrier spread from environment. Here we developed simple rapid loop-mediated isothermal amplification (LAMP) assay targeting leptospiral secY gene. Results Several reaction conditions LAMP were optimized ensure...
Leptospirosis is a zoonotic disease that has been reported in Malaysia and associated with recent trend of recreational activities among the youth. Thus, efforts such as educational interventions high-risk populations, especially youth, are key to increasing public awareness regarding leptospirosis. This paper presents findings pilot study wherein an intervention using gamification method was used determine changes leptospirosis knowledge On this note, students from university Seremban...
The zoonotic disease leptospirosis is caused by pathogenic species of the genus Leptospira. With advancement studies in leptospirosis, several new are being reported. It has always been a query, whether Leptospira species, serovars, and strains isolated from different geographical locations contribute to difference presentations severity. In an epidemiological surveillance study performed Malaysia, we seven novel intermediate saprophytic (Leptospira semungkisensis, fletcheri, langatensis,...
Background: Leptospirosis is a zoonotic and re-emerging disease caused by the Leptospira spp. Human leptospirosis presents with wide range of symptoms often being misdiagnosed other diseases. It well-known that broad clinical presentations severity depend on individual's age immune status. However, species also contribute to vast variation in presentations. Hence, this study aimed evaluate virulence three pathogenic (ST 238 L. interrogans, ST 242 weillii, 143 borgepetersenii) six novel (L....
The data provided in this article is the genomic sequence of new Leptospira isolate, interrogans strain HP358 (L. HP358) isolated from rodent, Sundamys muelleri (S. muelleri), captured human leptospirosis suspected area, forest environment, Hulu Perdik, Selangor. kidney rodent was cultured, and DNA pure isolate extracted sequenced. de novo assembly genome generated 118 contigs with N50 133,176bp. size L. determined a length 4,808,724 35.01% G+C content 229 subsystems, 5236 coding sequences...