A5087598618- Genetic Associations and Epidemiology
- Liver Disease Diagnosis and Treatment
- Diabetes and associated disorders
- Sepsis Diagnosis and Treatment
- Cardiomyopathy and Myosin Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Nuclear Structure and Function
- RNA Research and Splicing
- COVID-19 diagnosis using AI
- Malaria Research and Control
- Immune responses and vaccinations
- interferon and immune responses
- Mosquito-borne diseases and control
- Influenza Virus Research Studies
- Molecular Biology Techniques and Applications
- Immunotherapy and Immune Responses
- Invertebrate Immune Response Mechanisms
- Machine Learning in Healthcare
- Nutrition, Genetics, and Disease
- Single-cell and spatial transcriptomics
- Genomics and Rare Diseases
- Immunodeficiency and Autoimmune Disorders
- Tuberculosis Research and Epidemiology
- vaccines and immunoinformatics approaches
New York University Abu Dhabi
2022-2025
Moscow Institute of Thermal Technology
2024
Centre for Human Genetics
2022-2024
University of Oxford
2022-2024
University of Kent
2019
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine immunogenicity varies between individuals, and immune responses correlate with efficacy. Using data from 1,076 participants enrolled in ChAdOx1 nCov-19 efficacy trials the United Kingdom, we found that inter-individual variation normalized antibody against SARS-CoV-2 spike its receptor-binding domain (RBD) at 28 days after first vaccination shows genome-wide significant association major histocompatibility complex...
Myosin VI is involved in many cellular processes ranging from endocytosis to transcription. This multifunctional potential achieved through alternative isoform splicing and interactions of myosin with a diverse network binding partners. However, the interplay between these two modes regulation remains unexplored. To this end, we compared different partners their by exploring kinetic properties recombinant proteins distribution mammalian cells using fluorescence imaging. We found that...
Clinical evidence suggests that some patients diagnosed with coronavirus disease 2019 (COVID-19) experience a variety of complications associated significant morbidity, especially in severe cases during the initial spread pandemic. To support early interventions, we propose machine learning system predicts risk developing multiple complications. We processed data collected from 3,352 patient encounters admitted to 18 facilities between April 1 and 30, 2020, Abu Dhabi (AD), United Arab...
Existing prognostic tools mainly focus on predicting the risk of mortality among patients with coronavirus disease 2019. However, clinical evidence suggests that COVID-19 can result in non-mortal complications affect patient prognosis. To support stratification, we aimed to develop a system predicts common COVID-19. In this retrospective study, used data collected from 3,352 encounters admitted 18 facilities between April 1 and 30, 2020, Abu Dhabi (AD), UAE. The hospitals were split based...
Myosin VI is involved in a variety of cellular processes ranging from endocytosis to transcription. This multi-functional potential achieved through alternative isoform splicing and the interaction with diverse network binding partners. However, interplay between two modes regulation remains unexplored. To this end, we have compared different partners, Dab2 CALCOCO2/NDP52, their myosin splice isoforms. We found that both isoforms adopt an auto-inhibited state are subsequently activated by...