A5069298770- Antifungal resistance and susceptibility
- Bacterial biofilms and quorum sensing
- Legionella and Acanthamoeba research
- Bee Products Chemical Analysis
- Insect and Pesticide Research
- Heavy metals in environment
- Phytochemicals and Antioxidant Activities
- Parasitic Diseases Research and Treatment
- Isotope Analysis in Ecology
- Cystic Fibrosis Research Advances
- Systemic Sclerosis and Related Diseases
- Antimicrobial Peptides and Activities
- Fermentation and Sensory Analysis
- Plant Stress Responses and Tolerance
- Pediatric health and respiratory diseases
- Fungal Infections and Studies
- Fungal Biology and Applications
- Plant Micronutrient Interactions and Effects
- Peatlands and Wetlands Ecology
- Mycotoxins in Agriculture and Food
- Constructed Wetlands for Wastewater Treatment
University of Debrecen
2021-2025
Given the risk of Candida albicans overgrowth in gut, novel complementary therapies should be developed to reduce fungal dominancy. This study highlights antifungal characteristics a Bacillus subtilis-derived secondary metabolite, surfactin with high potential against C. albicans. Surfactin inhibited growth following 1-hour exposure, addition reduced adhesion and morphogenesis. Specifically, did not affect level reactive oxygen species but increased glutathione. Surprisingly, ethanol...
Abstract Metal contamination poses a high risk for organisms, especially those with extensive food chain relevancy. Thus, elevated concentration of metals is considered major cause concern in crops. This study aimed to evaluate the short-term responses sorghum and Sudan grass different Cd/Zn doses complex germination test by assessing growth parameters, tissue metal concentrations, interaction accountant ecophysiological elemental alterations. To do so, radicle hypocotyl length were...
Candida auris is a dangerous fungal pathogen that causes outbreaks in health care facilities, with infections associated high mortality rate. As conventional antifungal drugs have limited effects against the majority of clinical isolates, new and innovative therapies are urgently needed.
is frequently associated with biofilm-related invasive infections. The resistant profile of these biofilms necessitates innovative therapeutic options, where quorum sensing may be a potential target. Farnesol and tyrosol are two fungal quorum-sensing molecules antifungal effects at supraphysiological concentrations. Here, we performed genome-wide transcript profiling
Soil contamination caused by the presence of Cd and excess amount Zn is a widespread concern in agricultural areas, posing significant risks to growth development crops. In this paper, early-stage metal (Cd Zn) accumulation potential rapeseed (Brassica napus L.) grown under different application schemes were assessed determining radicle hypocotyl length micro- macro elemental composition plantlets after 24, 72, 120 h. The results indicated that single co-application significantly reduced...
In this study, growth and ionomic responses of three duckweed species were analyzed, namely Lemna minor, Landoltia punctata, Spirodela polyrhiza, exposed for short-term periods to hexavalent chromium or nickel under laboratory conditions. It was found that different had distinct patterns can change considerably due metal treatments. The results also show that, because the stress-induced increase in leaf mass-to-area ratio, studied showed order uptake efficiency if plant area used as unit...
A comprehensive understanding of carbon cycling pathways in the soil-plant system is needed to develop models that accurately predict global reservoir responses anthropogenic perturbations. Honey a carbon-rich natural food produced by wild and managed pollinating insects all over world; composition single sample function millions pollinator-plant interactions. We studied
Abstract Tyrosol, a secondary metabolite of Candida species, regulates fungal morphogenesis, and its application may represent novel innovative therapy against emerging multi-resistant superbug such as auris . In the current study, effects tyrosol on growth, redox homeostasis, intracellular microelement contents activities virulence-related enzymes released by C. were examined. To gain further information about effect exposure, we revealed gene transcriptional changes using total...
Abstract Candida auris is frequently associated with biofilm-related invasive infections. The resistant profile of these biofilms necessitates innovative therapeutic options, where quorum sensing may be a potential target. Farnesol and tyrosol are two fungal quorum-sensing molecules antifungal effects at supraphysiological concentrations. To date there has been no high-throughput comparative molecular analysis regarding the background farnesol– or tyrosol-related against C. biofilms. Here,...
Honey is thought to be a food source with indefinite shelf life - this statement questioned in present work by analysing the 5-hydroxymethylfurfural (HMF) content of unique series old products from 1959 2020. Two special are included where honey was produced and kept yearly same beekeeper for 30 years. Application development carried out White method scaling down volumes analysis. The HMF acacia honeys vary wide range (9-1320 mg/kg honey), but tendentially increase age. However, rape...
Abstract Given the risk of Candida albicans overgrowth in gut, novel complementary therapies should be developed to reduce fungal dominancy. This study highlights antifungal characteristics a Bacillus subtilis -derived secondary metabolite, surfactin with high potential against C. . Surfactin inhibited growth following 1-hour exposure, addition reduced adhesion and morphogenesis. Specifically, did not affect level reactive oxygen species but increased glutathione. Surprisingly, ethanol...
Abstract The antifungal resistance threat posed by Candida auris necessitates bold and innovative therapeutic options. Farnesol, a quorum-sensing molecule with potential and/or adjuvant effect; it may be promising candidate in alternative treatment regimens. To gain further insights into the farnesol-related effect on C. , genome-wide gene expression analysis was performed using RNA-Seq. Farnesol exposure resulted 1,766 differentially expressed genes. Of these, 447 304 genes at least...