A5040351029- Synthesis and biological activity
- Petroleum Processing and Analysis
- Catalysis and Hydrodesulfurization Studies
- Biodiesel Production and Applications
- Computational Drug Discovery Methods
- Organic Chemistry Cycloaddition Reactions
- Enzyme function and inhibition
- Bioactive Compounds and Antitumor Agents
- Neuropeptides and Animal Physiology
- Mass Spectrometry Techniques and Applications
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Biological Evaluation
- Chemical and Environmental Engineering Research
- Peptidase Inhibition and Analysis
- Free Radicals and Antioxidants
- Crystallization and Solubility Studies
- Diabetes and associated disorders
- Metal Extraction and Bioleaching
- Extraction and Separation Processes
- Hydrocarbon exploration and reservoir analysis
- Estrogen and related hormone effects
- Cancer therapeutics and mechanisms
- Catalysis for Biomass Conversion
- Chemical Reaction Mechanisms
Ecopetrol (Colombia)
2016-2017
Instituto Colombiano del Petróleo y Energías de la Transición - Icpet
2016-2017
University of Cartagena
2007-2012
Industrial University of Santander
2010
Fundación Ciencias Exactas y Naturales
2009
Abstract A theoretical study for the determination of chemical reactivity a series 2‐adamantyl‐thiazolidine‐4‐one derivatives was performed. These molecules are inhibitors inverse transcriptase activity human immunodeficiency virus type 1 (HIV‐1) that prevents replication HIV‐1 in cells without causing an appreciable effect on other retroviral particles or cellular polymerases. To determine nature bond, enzyme substrate used quantum similarity molecular calculations, using alignment...
Abstract A group of presumed drug‐like molecules that possess high in silico affinity for angiotensin‐converting enzyme 2 were computationally designed. This is a promising new target both cardiorenal disease and some coronavirus infections. set substrate analogous optimized by means the LeapFrog module SYBYL package. Later, Molinspiration Molsoft used screening out compounds with low oral bioavailability. Similarly, OSIRIS was having serious side effects. At end several stages screening,...
A methodology for structurally representing the molecules of three Colombian vacuum residues (538+ °C) and one Mexican atmospheric residue (300+ is reported. Information obtained by Fourier transform ion cyclotron resonance mass spectrometry coupled to positive electrospray ionization, negative pressure photoionization sources conventional standardized analytical methods was used molecular representation samples. The generation performed a Monte Carlo technique, obtaining set representative...