Lucanus Steven Koldewyn

ORCID: 0000-0003-3139-4164
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About
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Research Areas
  • Mesenchymal stem cell research
  • Proteoglycans and glycosaminoglycans research
  • Hematological disorders and diagnostics

The Spine Institute
2022

Bone marrow aspirate concentrate (BMC) is commonly used as a therapeutic agent to resolve orthopedic injuries, using its unique cellularity reduce inflammation and prime the region for repair. The aspiration of bone performed either sodium citrate (SC) or heparin (HS) an anticoagulant processed via centrifugation cellular constituents. To date, consideration impact two anticoagulants on mesenchymal stem/stromal cell (MSC) population has been overlooked. current study assesses differences in...

10.1155/2022/8259888 article EN cc-by Stem Cells International 2022-07-22

Background: The field of orthobiologics traditionally utilizes cellular products, including bone-marrow aspirate concentrate (BMAC), micronized adipose tissue, and platelet preparations to address pain from degenerative processes, orthopedic injuries medical conditions characterized by chronic inflammation tissue degradation. For BMAC, maximizing the concentration mesenchymal stem cells (MSCs) in a reduced volume is thought allow for therapeutic delivery concentrate, secretome, extracellular...

10.22374/boj.v6i1.61 article EN cc-by Biologic Orthopedics Journal 2024-04-24
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