A5088563140- Mesenchymal stem cell research
- Diabetes Management and Research
- Reconstructive Surgery and Microvascular Techniques
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Thyroid Disorders and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Selenium in Biological Systems
- Diphtheria, Corynebacterium, and Tetanus
- Intramuscular injections and effects
- Wound Healing and Treatments
- Vitamin D Research Studies
Universidade Federal do Rio Grande do Sul
2015-2019
Hospital de Clínicas de Porto Alegre
2015
Nonthyroidal illness syndrome (NTIS) is marked by low T3 and high reverse levels. The physiopathology poorly understood but involves oxidative stress-induced disruption of the iodothyronine deiodinases, which activate or inactivate thyroid hormones. Selenium, an essential trace element, exerts antioxidant function mainly through thioredoxin reductase (TRx) glutathione peroxidase (GPx) redox-regulating systems. We evaluated effect sodium selenite on IL6-induced deiodinase function. Cell lines...
To evaluate the use of adipose-derived stem cells (ADSC) in reducing necrosis area an experimental model cutaneous ischemic flap rats submitted to subcutaneous nicotine injection simulate a smoker patient.In study, 30 were enrolled and divided into two groups 15 animals all create flaps on their backs. Other 10 used only obtain adipose tissue derived (ADSC). The first group (n=15) received ADSC treatment at end surgery while other group, control (n=15), no interventions. After euthanasia,...