A5038470007- Pharmaceutical Practices and Patient Outcomes
- Public Health in Brazil
- Patient Safety and Medication Errors
- Cardiac Arrest and Resuscitation
- Antifungal resistance and susceptibility
- Essential Oils and Antimicrobial Activity
- Microencapsulation and Drying Processes
- Nail Diseases and Treatments
- Characterization and Applications of Magnetic Nanoparticles
- Pesticide Exposure and Toxicity
- Surfactants and Colloidal Systems
- Pharmaceutical studies and practices
- Phytochemistry Medicinal Plant Applications
- Advancements in Transdermal Drug Delivery
- Nanoparticle-Based Drug Delivery
- Pharmacovigilance and Adverse Drug Reactions
- Analytical Chemistry and Chromatography
- Polysaccharides Composition and Applications
- Biosimilars and Bioanalytical Methods
- Botanical Research and Applications
- Schizophrenia research and treatment
- Virus-based gene therapy research
- Plant-Derived Bioactive Compounds
- Safe Handling of Antineoplastic Drugs
- Pharmacy and Medical Practices
Universidade Federal do Rio Grande do Norte
2007-2024
Universidade Federal Fluminense
2002
National Oceanography Centre
2002
Fundação Oswaldo Cruz
1996-1997
Aims: To investigate the effects of periodontitis, alone or in combination with dexamethasone treatment, on growth, viability, and cyclicity ovarian follicles mice. Study Design: The animals were divided into four different groups, kept polyethylene boxes, eight per box. Place Duration Study: It was performed Federal University Ceara, between January 2021 December 2021. Methodology: Swiss mice (N=32) groups: naive, treatment dexamethasone, periodontitis dexamethasone. induce periodontal...
Amphotericin B remains the drug of choice for treatment most systemic fungal infections in immunodeficient patients. Because high incidence adverse reactions clinical use is rather limited. To reduce its toxicity new delivery systems has been suggested. Nevertheless, these carriers present several technological drawbacks that impair development a marketable product. The aim this work was to develop an microemulsion order increase efficacy and decrease compared Fungizon, widely know...
Objective To identify risk factors for potential Drug-Related Problems (DRP) at admission in hospitalized patients. Methodology Prospective cohort study conducted adults patients (May 2016 to May 2018) a general tertiary care hospital Brazil. Potential DRP were detected by daily review of 100% electronic medication orders pharmacists and classified the Pharmaceutical Care Network Europe classification system (PCNE version 6.2). For identification DRP, backward stepwise logistic regression...
The drawbacks related to the use of viral vectors in gene therapy have been stimulated research non-viral strategies such as cationic nanoemulsions. aim this work was develop a stearylamine-containing nanoemulsion for purpose. formulation chosen from Pseudo-Ternary Phase Diagram and had its long-term stability assessed by Dynamic Light Scattering Analysis during 180 days at 4 degrees C, 25 C 40 C. Besides, studies sterilization scale up product were conducted. It demonstrated that proposed...
Objectives To evaluate the incidence and types of drug-related problems (DRP) in a general teaching hospital to acceptability pharmaceutical interventions by medical team. Design Prospective cohort study during 2 years. Setting Conducted Brazilian University Hospital. Participants The patient consisted 9303 patients with total 12 286 hospitalisation episodes. Primary outcome measures DRP detected pharmacists’ review 100% medication orders using Pharmaceutical Care Network Europe 6.2...
Although there is a conflict between the treatment benefits for single individual and society, restrictions on antibiotic use are needed to reduce prevalence of resistance these drugs, which main result irrational use. Brazil, cataloged as pharmemerging market, has implemented restrictive measures consumption antibiotics. The objective this study was investigate quality antimicrobial prescriptions user knowledge their with drugs.A two-stage cross-sectional, combined stratified survey...
The crude latex of Crown-of-Thorns (Euphorbia milii var. hislopii) is a potent plant molluscicide and promising alternative to the synthetic molluscicides used in schistosomiasis control. present study was undertaken investigate embryofeto-toxic potential E. latex. part comprehensive safety evaluation this molluscicide. Lyophilized (0, 125, 250 500 mg/kg body weight) corn oil given by gavage Wistar rats (N = 100) from days 6 15 pregnancy cesarean sections were performed on day 21 pregnancy....
In this article, a nanosuspension of AmB was prepared and mixed with the preformed parenteral emulsion Lipofundin® subjected to high-pressure homogenization (SolEmuls® technology). Characterization performed by photon correlation spectroscopy (PCS), laser diffractometry (LD), zeta potential measurements. Drug incorporation studied using light microscopy. The produced emulsions were further investigated comparing them commercially available Fungizone® in regard antifungal efficiency toxicity....
Objective Development and internal validation of a clinical tool for assessment the risk adverse drug reactions (ADR) in hospitalized patients. Methodology Nested case-control study an open cohort all patients admitted to general hospital. Cases ADR were matched two controls. Eighty four patient variables collected at time analyzed by conditional logistic regression. Multivariate regression with clustering cases random sample 2/3 respective controls, baseline odds-ratio corrected estimate...
To assess the analgesic efficacy of subcutaneous lidocaine and multimodal analgesia for chest tube removal following heart surgery.Sixty volunteers were randomly allocated in two groups; 30 participants experimental group given 1% lidocaine, controls a regime comprising systemic anti-inflammatory agents opioids. The intensity quality pain trait state anxiety assessed. association between independent variables final outcome was assessed by means Chi-squared test with Yates' correction...
Aqueous suspensions containing magnetic microparticles have been increasingly used in biosciences and biotechnology. This work describes an experimental procedure to produce superparamagnetic microparticles. The particles were prepared based on the coprecipitation of iron salts alkaline medium. Afterwards, characterization was performed. Characterization data demonstrated that magnetite dominant phase analyzed sample, 50% them size range 0.5-5 microm. results suggest protocol provided a...
The relationship between internal wave (IW) signatures in Synthetic Aperture Radar (SAR) images and wind velocity is investigated. effect of the relative to IW propagation direction on signature studied by means a defined mode parameter ( S m ). that quantifies intensity profile relation mean backscatter image background. A contrast model based simple first-order Bragg scattering theory combined with hydrodynamic modulation explain signatures. It takes into account short-scale surface waves...