About
Contact & Profiles
A5035740015
Research Areas
- Peptidase Inhibition and Analysis
- Neuropeptides and Animal Physiology
- Chemical Synthesis and Analysis
Osaka University of Pharmaceutical Sciences
2020
Most enzymes act on more than a single substrate. There is frequently need to block the production of pathogenic outcome enzymatic activity substrate but avoid blocking others its catalytic actions. Full might cause severe side effects because some products that catalysis may be vital. Substrate selectivity required not possible achieve by residues an enzyme. That basis for "Substrate Selective Inhibitors" (SSI), and there are several molecules characterized as SSI. However, none have yet...
10.1371/journal.pcbi.1007713
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PLoS Computational Biology
2020-03-20
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