A5071805322- Traditional Chinese Medicine Analysis
- Spectroscopy and Chemometric Analyses
- Traditional Chinese Medicine Studies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Flavonoids in Medical Research
- Chromatography in Natural Products
- Natural product bioactivities and synthesis
- Advanced Chemical Sensor Technologies
- Medicinal Plant Pharmacodynamics Research
- Pharmacological Effects of Natural Compounds
- Ginkgo biloba and Cashew Applications
- Neurological Disease Mechanisms and Treatments
- Bone Metabolism and Diseases
- Bone health and osteoporosis research
- Metabolomics and Mass Spectrometry Studies
- Polysaccharides and Plant Cell Walls
- Viral Infectious Diseases and Gene Expression in Insects
- Nutrition and Health in Aging
- Bee Products Chemical Analysis
- Total Knee Arthroplasty Outcomes
- Seaweed-derived Bioactive Compounds
- Biomarkers in Disease Mechanisms
- Macrophage Migration Inhibitory Factor
- Supramolecular Self-Assembly in Materials
- Bioactive Compounds in Plants
China Pharmaceutical University
2022-2025
Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine
2016-2024
Beijing University of Chinese Medicine
2019-2023
Fujian University of Traditional Chinese Medicine
2019-2022
Jiangxi University of Traditional Chinese Medicine
2021
Guangzhou University of Chinese Medicine
2016
Abstract Spectra-structure interrelationship is still the weakness of NIR spectral assignment. In this paper, a comprehensive investigation from chemical structural property to natural compounds was carried out for Surprisingly, we discovered that absorption frequency skeleton structure with sp 2 hybridization higher than one 3 hybridization. Specifically, substituent another vital factor be explored, first theory discovery demonstrated intensity methyl substituted benzene at 2330 nm has...
Enhancing the dissolution, permeation and absorption of active components with low solubility poor permeability is crucial for maximizing therapeutic efficacy optimizing functionality. The objective this study to investigate potential natural polysaccharides as carriers improve biopharmaceutical properties components.In study, we employed four representative flavonoids in Astragali Radix, namely Calycosin-7-O-β-D-glucoside (CAG), Ononin (ON), Calycosin (CA) Formononetin (FMN), a...
This research introduces a systems theory-driven framework to integration artificial intelligence (AI) into traditional Chinese medicine (TCM) research, enhancing the understanding of TCM's holistic material basis while adhering evidence-based principles. Utilizing System Function Decoding Model (SFDM), progresses through define, quantify, infer, and validate phases systematically explore basis. It employs dual analytical approach that combines top-down, theory-guided perspectives with...
Abstract Chinese medicine processing (CMP) is a unique pharmaceutical technology that distinguishes it from natural medicines. Current research primarily focuses on changes in chemical components to understand the mechanisms behind efficacy enhancement processing. However, this paper presents novel perspective biopharmaceutics of CMP. It provides comprehensive overview current research, emphasizing two crucial aspects: role ‘heat’ during and utilization adjuvants. The highlights generation...
Abstract: The self-assembling aggregated structures of natural products have gained significant interest due to their simple synthesis, lack carrier-related toxicity, and excellent biological efficacy. However, the mechanisms assembly ability traverse gastrointestinal (GI) barrier remain unclear. This review summarizes various intermolecular non-covalent interactions structures, drawing on research indexed in Web Science from 2010 2024. Cheminformatics analysis self-assembly behaviors small...
Type 1 diabetes (T1D) is a metabolic disease commonly affecting adolescents and causing various health complications. Corn silk (CS), traditional Chinese medicine with medicinal edible properties, has been extensively researched for its anti-diabetes anti-inflammatory effects. This study aimed to investigate the hypoglycemic effect of CS extract on T1D mice by modulating composition gut microbiota. The results demonstrated that had significant therapeutic STZ-induced reducing fasting blood...
Red ginseng (RG) was widely used as traditional Chinese medicine (TCM) or dietary supplement. However, few researches had been reported on the red polysaccharide (RGP).
Purpose: Asperosaponin VI (ASP VI) as an active ingredient of Dipsacus asperoides , which has a wide range biological and pharmacological activity. However, its development application are restricted due to the poor gastrointestinal permeability oral bioavailability. This investigation aims reveal influence self-assembled structure by interaction between ASP endogenous components NaTC and/or DOPC in environment on biopharmaceutical properties, novelty elucidated molecular mechanism for...
The present study aimed to investigate the effect of co‑culture fibroblast‑like synoviocytes (FLS) with human umbilical cord‑mesenchymal stem cells (UC‑MSCs) on rheumatoid arthritis (RA) and understand mechanisms that mediate induced changes. FLS UC‑MSCs were isolated cultured individually, then or without UC‑MSCs. phenotype was analyzed prior co‑culture. successfully expanded, exhibited a morphology. Enzyme‑linked immunosorbent assay (ELISA) reverse transcription‑quantitative polymerase...
Abstract Introduction The on‐line analysis of active pharmaceutical ingredients (APIs) during the extraction process in herbal medicine is a challenge. Establishing reliable and robust model critical procedure for industrial application near‐infrared (NIR) technology. Objective To evaluate advantages NIR development using system optimisation strategy, Glycyrrhiza uralensis Fisch was used as case. content liquiritin glycyrrhizic acid monitored pilot scale three batches. Methods...