A5020276010- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Drug Transport and Resistance Mechanisms
- Pharmacological Effects and Toxicity Studies
- Fatty Acid Research and Health
- Gestational Diabetes Research and Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Neonatal Health and Biochemistry
Affiliated Hospital of Southwest Medical University
2022-2024
Abstract The objective of this study is to investigate the expression and influence adenosine triphosphate-sensitive potassium channel (KATP) in human umbilical arterial smooth muscle cells (HUASMCs) patients with hypertensive disorders pregnancy (HDP). Western blotting was used detect protein levels KATP inwardly rectifying (Kir)6.1 sulphonylurea receptor (SUR)2B subunits HUASMCs from normal parturients (NP), gestational hypertension (GH), chronic (CH), preeclampsia (PE) superimposed...
Objective To characterize the bile acid metabolomic profiles of umbilical cord blood and meconium in healthy newborns. Methods Fifteen newborns, which born Obstetrics Department Affiliated Hospital Southwest Medical University between July 1 August 31, 2023, were selected as study subjects. Umbilical samples collected, metabolomics analyzed using ultra-high performance liquid chromatography-tandem mass spectrometry. Results The ratio primary to secondary acids was significantly higher than...
The offspring of pregnant women with gestational diabetes mellitus (GDM) are vulnerable to be glucometabolic disorders. However, date, few current studies focused on the associations maternal accumulated glucose exposure before delivery neonatal disorders and large for age (LGA) infants. This study is aimed at exploring fructosamine (FMN) in GDM first 3 days life LGA subjects were women, who gave birth our hospital from September 1, 2018 January 31, 2021, their newborns. FMN adjusted by...