Hans-Martin Klein

ORCID: 0000-0003-3218-1945
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About
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Research Areas
  • Advanced MRI Techniques and Applications
  • Mesenchymal stem cell research
  • Tissue Engineering and Regenerative Medicine
  • Gallbladder and Bile Duct Disorders
  • Cardiac pacing and defibrillation studies
  • Cardiac Arrhythmias and Treatments
  • Electrospun Nanofibers in Biomedical Applications
  • Anatomy and Medical Technology
  • Spinal Fractures and Fixation Techniques
  • Pediatric Hepatobiliary Diseases and Treatments
  • Medical Imaging Techniques and Applications
  • Cardiac Imaging and Diagnostics
  • Urinary Tract Infections Management
  • Gastrointestinal disorders and treatments
  • Abdominal vascular conditions and treatments
  • Meningioma and schwannoma management
  • Digital Radiography and Breast Imaging
  • Radiation Dose and Imaging
  • Advanced X-ray and CT Imaging
  • Gastroesophageal reflux and treatments
  • Pluripotent Stem Cells Research
  • Pelvic and Acetabular Injuries
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Pelvic floor disorders treatments
  • Intestinal and Peritoneal Adhesions

Heinrich Heine University Düsseldorf
2005-2011

Diakonie Klinikum Jung-Stilling
2004-2008

Medical Radiological Research Center
2007

Federal Highway and Transport Research Institute
2004

Ihre-Radiologen
2002-2003

FH Aachen
1992-1997

RWTH Aachen University
1991-1996

Westfälische Hochschule
1993

Universitätsklinikum Aachen
1990

University of Münster
1986

To determine the value of diagnostic imaging in management mesenteric infarction.Within 8 years, 54 patients with infarction underwent before surgery, including plain radiography (n = 45), ultrasound (US) 29), small bowel follow-through examination 7), colon enema study angiography 16), and computed tomography (CT) 22). Clinical course, laboratory values, findings were considered diagnosis.Radiography US allowed correct diagnoses five 18 cases (28%). Only one 14 fluoroscopic examinations...

10.1148/radiology.197.1.7568858 article EN Radiology 1995-10-01

Cell transplantation for myocardial regeneration has been shown to have beneficial effects on cardiac function after infarction. Most clinical studies of intramyocardial cell were performed in combination with coronary artery bypass grafting (CABG). The contribution implanted stem cells could yet not be clearly distinguished from the effect CABG surgery. Our current phase 1 study focused safety and feasibility CD133+-enriched without its potential function.Ten patients end-stage chronic...

10.1532/hsf98.20061054 article EN The Heart Surgery Forum 2006-12-08

Functional improvement after acute myocardial ischaemia (MI) has been achieved by transplantation of different adult stem and progenitor cell types. It is controversial whether these types are able to form novel functional myocardium. Alternatively, graft-related or immune-related paracrine mechanisms may preserve existing myocardium, improve neovascularisation, affect tissue remodelling induce endogenous de novo formation We have applied an alternative somatic type, human cord-blood-derived...

10.1136/hrt.2007.139329 article EN Heart 2008-06-03

SummaryThe authors report their experiences gained from 19 patients with ventral or ventrolateral foramen magnum meningiomas operated on via the dorsolateral, suboccipital transcondylar access route. It is emphasized that microsurgical management of these lesions includes two important aspects which increase safety procedure: a meticulous preoperative planning based micro-anatomical details each patient, as well an individualized tailoring surgical approach. There were no deaths, and, in...

10.1007/978-3-7091-9450-8_23 article EN 1996-01-01

To investigate whether the sphincter area in women can be seen and quantified with intra-urethral ultrasound (IUUS). Currently, capacity is determined by clinical tests, vaginal palpation, urodynamics urethral pressure profile.A pilot study using IUUS was carried out 32 stress incontinent 12 healthy to enable urethra para-urethral tissue visualized. Round-tipped miniature transducer-containing (20 MHz) catheters (6 9 F) were tested. Both provided 15 frames per second. Real-time 360 degrees...

10.1111/j.1464-410x.1994.tb16618.x article EN British Journal of Urology 1994-09-01

Transmyocardial laser revascularization for angina relief and intramyocardial autologous endothelial progenitor cell injection neoangiogenesis may offer a new treatment strategy patients with intractable ischemic heart disease.Transmyocardial of bone marrow-derived CD133+ cells was performed in six highly symptomatic patients. channels were created isolated injected intramyocardially. All followed up minimum 6 months postoperatively.One patient died shortly after the operation due to...

10.1055/s-0029-1186199 article EN The Thoracic and Cardiovascular Surgeon 2010-01-13

We examined ways to improve energy efficiency in radiology by using regenerative and energy-friendly technology the construction operation of two radiological facilities.In years 2009 2010 an energy-optimized medical center with different clinical disciplines a practice was built. used production (photovoltaic system, 29.92 kWp). A heat exchanger also regain thermal support heating building, thereby reducing cooling consumption. The operates 1.5 T MRI machine computed tomography scanner....

10.1055/a-2021-7386 article DE RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 2023-03-16

To explore the usefulness of intraluminal ultrasound (US) for diagnostic imaging female urethra, 22 patients with different degrees urinary incontinence and 10 normal continence underwent examination by means a 20-MHz intravascular US system. Contiguous sections were used three-dimensional reconstructions on personal computer-based system in two patients. The circumference area internal urethral sphincter measured all patients; measurements obtained manual delineation inner outer contours...

10.1148/radiology.187.1.8451400 article EN Radiology 1993-04-01

Our goal was to assess the value of CT and MRI for detection bowel wall changes in experimentally induced mesenteric ischemia.in 18 female pigs, a percutaneous embolization superior artery performed with buthyl-2-cyanoacrylate Lipiodol (1:1) (experimental group). In six animals, only diagnostic imaging histologic evaluation were (control carried out 3, 6, 12 h after occlusion. Incremental (1 s scan time, 5 mm slice thickness, 7 increment, 120 kV/290 mAs) spiral (slice thickness mm, pitch...

10.1097/00004728-199603000-00016 article EN Journal of Computer Assisted Tomography 1996-03-01

To evaluate cardiac magnetic resonance imaging (MRI) using a 0.35 T system with open design.Eleven patients were examined in an MRI field strength of T. Myocardial function was assessed cine true fast steady-state precession sequences 2 planes. Perfusion images acquired T1-weighted gradient echo sequence. Late enhancement performed inversion recovery-prepared technique. Image quality 4-point score consensus. Signal-noise ratio measured.For functional imaging, average 1.65 (SD, 0.6). For...

10.1097/01.rct.0000238010.64931.c6 article EN Journal of Computer Assisted Tomography 2007-05-01

If traditional treatment of coronary artery disease has failed, intramyocardial transplantation CD133+ stem cells with the potential to improve myocardial function is an alternative approach treating ischemic cardiomyopathy. The INSTEM trial aims at evaluating safety and feasibility isolation subsequent in combination bypass grafting (CABG). Patients suffering from severe cardiomyopathy (ejection fraction ≫15% ≪35%) are enrolled this trial. Bone marrow harvested iliac crest purified up 99%....

10.1510/mmcts.2009.003947 article EN Multimedia Manual of Cardio-Thoracic Surgery 2010-01-01

Ziel: Die Untersuchung der diagnostischen Aussagekraft von Magnetresonanz-Tomographie (MRT), Arthrographie (AG) und Arthro-CT (ACT) bei Erkrankungen des Handgelenkes. Methodik: Insgesamt 346 Untersuchungen Handgelenkes wurden für einen dreijährigen Beobachtungszeitraum retrospektiv ausgewertet. Es 211 MRT, 151 Arthrographien 126 durchgeführt. Alle Diagnosen operativ (n = 78) oder durch den klinischen Verlauf in einer 6-monatigen Nachbeobachtung gesichert. Ergebnisse: Für die Diagnostik...

10.1055/s-2002-20103 article DE RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 2002-02-13

Hintergrund: Die Leber kann sich nach einer Teilresek­tion quantitativ und qualitativ sehr gut regenerieren. Unter bestimmten kriti­schen Grenze des prospektiven Leberrestvolumens (FLRV), geht eine Leberteilresektion dennoch mit großen Gefahr Lebersynthesestörung bis hin zur Leberinsuffizienz einher. Verschiedene Untersuchungen deuten auf einen wesentlichen Einfluss von Knochenmarksstammzellen (KMSZ) die Leberregeneration hin. Wir berichten hier über unsere Erfahrungen Kombination aus...

10.1055/s-0031-1271587 article DE Zentralblatt für Chirurgie - Zeitschrift für Allgemeine Viszeral- Thorax- und Gefäßchirurgie 2011-11-15

We have developed electroabsorption modulated DFB Lasers at 1305 nm using an identical InGaAlAs MQW core in the and EAM section. A 50Ω matching circuit is realized on-chip giving f3dB of 39.4 GHz. present 56 Gbit/s eyes with a dynamic extinction ratio 9.5 dB. The fiber coupled output power under modulation +5 dBm 45°C.

10.1049/cp.2013.1505 article EN 2013-01-01

Characterisation of focal liver lesions on computed tomography (CT) depends correct interpretation morphology and dynamic changes during bolus injection contrast medium. The aim this study was to develop a texture analysis concept for computer based CT images. 148 were investigated by serial CT. comprised 61 haemangiomas, 25 other benign (FNH/adenomas) 62 malignant (primary or secondary). FNH, adenomas histologically proven. Diameter 8-145 mm (mean 31 mm). Regions interest interactively...

10.1055/s-2008-1032713 article EN RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 1993-07-01

10.1016/s0140-6736(66)92905-9 article EN The Lancet 1966-09-01
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