A5066567815- Estrogen and related hormone effects
- Breast Cancer Treatment Studies
- Retinal Imaging and Analysis
- HER2/EGFR in Cancer Research
- Retinal Diseases and Treatments
- Surgical Simulation and Training
- Acute Myeloid Leukemia Research
- Anatomy and Medical Technology
- Glaucoma and retinal disorders
- Rheumatoid Arthritis Research and Therapies
- Augmented Reality Applications
- Nuclear and radioactivity studies
- Retinal and Optic Conditions
- Soft Robotics and Applications
- Monoclonal and Polyclonal Antibodies Research
- Advanced Breast Cancer Therapies
- Lung Cancer Treatments and Mutations
- Systemic Sclerosis and Related Diseases
- Artificial Intelligence in Healthcare
- Protease and Inhibitor Mechanisms
- COVID-19 diagnosis using AI
- Cell Adhesion Molecules Research
- Radiopharmaceutical Chemistry and Applications
- Brain Tumor Detection and Classification
- Blood Coagulation and Thrombosis Mechanisms
University of Southern Denmark
2018-2025
Maersk (Denmark)
2018-2025
Ramboll (United Kingdom)
2025
Steno Diabetes Centers
2018-2024
Odense University Hospital
1988-2024
Robotics Research (United States)
2021
University of Copenhagen
2021
Danish Breast Cancer Cooperative Group
2015
Aarhus University Hospital
1997-2009
Nordic Society of Gynecologic Oncology
2003
The development of standardised methods for ultrasound (US) scanning and evaluation synovitis activity by the OMERACT-EULAR Synovitis Scoring (OESS) system is a major step forward in use US diagnosis monitoring patients with inflammatory arthritis. variation interpretation disease on images can affect diagnosis, treatment outcomes clinical trials. We, therefore, set out to investigate if we could utilise neural network architecture Doppler images, using OESS scoring system.Two...
Two independent and consecutive randomized clinical trials, conducted by the American Gynecological Oncology Group an European-Canadian Intergroup, have shown superiority, in response rate, progression-free survival, overall of a cisplatin-paclitaxel regimen over cisplatin-cyclophosphamide given as first-line chemotherapy for women with advanced epithelial ovarian cancer. The results these studies, published median follow-up about 3 years, been updated 6.5-year follow-up: In each case, 11%...
Waste-to-energy (WtE) facilities present an attractive option for CO2 capture. In the study, post-combustion amine-based carbon capture with energy integration coupling to a district heating network has been explored Sysav waste-to-energy facility in city of Malmö, Sweden. The potential is 59 ton CO2/h or ~450.000 annually.Chemical process modeling using ProMax® conducted establish performance both 30% MEA and CESAR-1 solvents various optimizations. chemical combined THERMOFLEX®...
Existing deep learning (DL) algorithms lack the capability to accurately identify patients in immediate need of treatment for proliferative diabetic retinopathy (PDR). We aimed develop a DL segmentation model detect active PDR six-field retinal images by annotation new vessels and preretinal hemorrhages. identified classified at level 4 International Clinical Diabetic Retinopathy Disease Severity Scale collected Island Funen from 2009 2019 as part Danish screening program (DR). A certified...
The aim of this study was to make prognostic comparisons between the modified scheme Pedersen et al. definitions Tavassoli and Ridolfi criteria for medullary carcinomas. Sixty breast carcinomas primarily diagnosed as were reclassified into typical carcinoma (TMC), atypical (AMC) non-medullary (NMC) according three classifications. classification proved be superior two other schemes in discriminating survival differences groups TMC, AMC NMC. All 13 patients with TMC are still alive indicating...
We describe an immunohistochemical method using a monoclonal antibody to localize estrogen receptors (ER) in formalin-fixed, paraffin-embedded tissue. The avidin-biotin-peroxidase complex was used, preceded by trypsin treatment expose antigenic sites. In 111 breast cancer specimens studied simultaneously dextran-coated charcoal (DCC) assay and the paraffin section method, agreement on receptor status found 101 (91%) specimens. Quantitative staining features showed high degree of correlation...
We have previously shown that neural network technology can be used for scoring arthritis disease activity in ultrasound images from rheumatoid (RA) patients, giving scores according to the EULAR-OMERACT grading system. now further developed architecture of this and here present a new idea applying cascaded convolutional (CNN) design with even better results. evaluate generalisability method on unseen data, comparing CNN an expert rheumatologist.The were graded by rheumatologist synovitis...
Of the 3 802 patients enrolled in DBCG 77 protocols, 863 developed clinical recurrence within a median follow-up time of 4.9 years (range 2.0–7.0). More than 69% these had their first confined to single anatomical site and 12% more two metastatic sites. The most common sites were bone (35%), lung (23%), skin (22%), regional lymph nodes (16%). observation period after was 3.6 0.8–6.4). Survival significantly related both location number metastases. Patients who given adjuvant chemotherapy...
Tumour angiogenesis and the levels of plasminogen activator inhibitor type 1 (PAI-1) are both informative prognostic markers in breast cancer. In cell cultures animal model systems, PAI-1 has a proangiogenic effect. To evaluate interrelationship level cancer, we have evaluated value those factors total 228 patients with primary, unilateral, invasive at median follow-up time 12 years. Microvessels were immunohistochemically stained by antibodies against CD34 quantitated Chalkley counting...
Several reports have claimed that perioperative blood transfusion promotes recurrence and death after cancer surgery. We studied the effect of in 315 patients who had radical resection for carcinoma colon rectum. The disease recurred 113 (42%) 268 transfused patients, versus 15 (32%) 47 non-transfused (P = 0.2). Of 102 (38%) died cancer, 13 (28%) group 5-year recurrence-free survival rate was 0.59 0.72 0.10). When differences confounding background variables were accounted by Cox multiple...
MOPS is a platform for surgical robotics research. It consists of hardware and software components building robot systems based on existing arms. The reference system presented in this paper has two arms, each with an adapter mounting actuating different types instruments. Additionally, the high-resolution stereo camera simple operator console haptic devices foot pedals teleoperating manipulators. Software are Robot Operating System (ROS) to keep them modular reusable hardware. We evaluate...
We present a novel application of Learning from Demonstration to realize fully autonomous bi-manual surgical suturing task, including needle pick up, insertion, re-grasping, extraction and hand-over. Surgical action primitives are learned single human demonstration encoded into an library which they pulled compose more elaborate tasks at planning/execution time. The method is demonstrated in non-clinical setting, using unmodified instruments with custom robot system. use stereo vision...
The incidence of diabetes continues to increase across the world. As number patients rises, so does need for educated health care professionals. Diabetic retinopathy (DR) remains one primary complications in diabetes, and screening has proved be a cost-effective measure avoid DR-related blindness. Denmark an established programme, but no formal training people responsible analysing retinal images.We here present online learning platform that offers diabetic eye course professionals...