- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrospinal fluid and hydrocephalus
- Cervical and Thoracic Myelopathy
- Hip and Femur Fractures
- Brain Metastases and Treatment
- Emergency and Acute Care Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Marine Toxins and Detection Methods
- Cardiac, Anesthesia and Surgical Outcomes
- Nerve Injury and Rehabilitation
- Trauma and Emergency Care Studies
- Pituitary Gland Disorders and Treatments
- Cardiac Arrest and Resuscitation
- Long-Term Effects of COVID-19
- Spinal Cord Injury Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Cardiovascular and Diving-Related Complications
- Neurosurgical Procedures and Complications
- Heart Rate Variability and Autonomic Control
- Spinal Fractures and Fixation Techniques
- Photoreceptor and optogenetics research
- Non-Invasive Vital Sign Monitoring
- Frailty in Older Adults
National Neuroscience Institute
2021-2025
National University of Singapore
2015-2019
Little information is available on a direct comparison of the antibacterial efficacy light emitting diode (LEDs) different peak wavelengths. Thus, objective this study was to evaluate effect LEDs three wavelengths bacterial inactivation.Lactobacillus plantarum, Staphylococcus aureus and Vibrio parahaemolyticus were illuminated with 405, 460 520 nm at 4, 10 25°C respectively. Inactivation curves plotted fitted using Gompertz Model. Illumination 405 LED produced significant inactivation (P <...
Thoracic spinal meningiomas (TSMs) are common intradural extramedullary tumors and usually surgically treated. Although surgery generally results in positive outcomes, some patients experience residual or new neurological impairments. The authors conducted a multicenter cohort study to investigate prognostic factors that affect functional recovery following TSM resection. A retrospective from 3 tertiary centers was included all who underwent resection between 2015 2023. Patients had minimum...
Objective: Multimorbidity burden across disease cohorts and variations in clinico-radiographic presentations within normal pressure hydrocephalus (NPH) confound its diagnosis, the assessment of amenability to interventions. We hypothesized that novel imaging techniques such as 3-directional linear morphological indices could help distinguishing between vs. non-hydrocephalus correlate with responsiveness external lumbar drainage (CSF responsiveness) NPH subtypes. Methodology: Twenty-one...
Owing to the scarcity of randomized controlled trials guide treatment for decompression illness (DCI), there are many unanswered questions about its management. Apart from reviews and expert opinion, surveys that report practice patterns provide information useful management strategies. Hence, this study aimed identify current preferences DCI amongst diving physicians in Singapore.An anonymous web-based questionnaire was sent known Singapore. The demographics respondents were captured....
Triage trauma scores are utilised to determine patient disposition, interventions and prognostication in the care of patients. Heart rate variability (HRV) heart complexity (HRC) reflect autonomic nervous system derived from electrocardiogram (ECG) analysis. In this study, we aimed develop a model incorporating HRV HRC, predict need for life-saving (LSI) patients, within 24 h emergency department presentation.We included adult patients (≥ 18 years age) presenting at Singapore General...
Abstract Introduction Aneurysmal subarachnoid haemorrhage (aSAH) is a condition with significant morbidity and mortality. Traditional markers of aSAH have established their utility in the prediction outcomes while frailty been validated other surgical specialties. We aimed to compare predictive value indices sarcopaenia osteopaenia, against traditional for outcomes. Methods An observational study tertiary neurosurgical unit on 51 consecutive patients ruptured was performed. The best...
Background: Primary intracranial malignant melanoma (PIMM) is an uncommon brain malignancy that often diagnosed after excluding metastases.It life-limiting with early relapse and portends a poor prognosis.Given its rarity, there are no well-defined standard treatments.Case Description: Here we described middle-aged lady who has underlying nevus of Ota presents new onset vision changes unilateral headaches.The initial radiological diagnosis was thought to be sphenoid wing meningioma but...