A5040338200- Dementia and Cognitive Impairment Research
- Parkinson's Disease Mechanisms and Treatments
- Alzheimer's disease research and treatments
- Advanced Neuroimaging Techniques and Applications
- Ginkgo biloba and Cashew Applications
- Climate Change and Health Impacts
- Porphyrin Metabolism and Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Neurological diseases and metabolism
- Sleep and Wakefulness Research
- Neurological disorders and treatments
- Air Quality and Health Impacts
- Iron Metabolism and Disorders
- Noise Effects and Management
- Down syndrome and intellectual disability research
- Sleep and related disorders
Yonsei University
2017-2024
International St. Mary's Hospital
2023-2024
Catholic Kwandong University
2023-2024
Gangnam Severance Hospital
2017-2023
Inje University Ilsan Paik Hospital
2023
Chung-Ang University
2023
Inje University Sanggye Paik Hospital
2023
Severance Hospital
2023
Abstract Objective Although chronic exposure to air pollution is associated with an increased risk of dementia in normal elderlies, the effect on rates cognitive decline Alzheimer's disease (AD) has not been elucidated. Methods In this longitudinal study, a total 269 patients mild impairment or early due AD evidence brain β‐amyloid deposition were followed‐up for mean period 4 years. Five‐year normalized hourly cumulative value each pollutant, such as carbon monoxide (CO), nitrogen dioxide...
Neuropsychiatric symptoms (NPS) are closely associated with cognitive decline in patients Parkinson disease (PD). We investigated which profiles of NPS the risk dementia PD mild impairment (PD-MCI).
This study aimed to determine the pattern of 18 F-fluorodeoxyglucose positron emission tomography (FDG-PET) related postmortem Lewy body disease (LBD) pathology in clinical Alzheimer (AD).FDG-PET scans were analyzed 62 autopsy-confirmed patients and 110 controls Alzheimer's Disease Neuroimaging Initiative. Based on neuropathologic evaluations Braak stage for neurofibrillary tangle, Consortium Establish a Registry AD score neuritic plaque, Lewy-related pathology, subjects classified into...
This study aimed to determine the neuropsychological differences between patients with early-stage Alzheimer's disease (AD) and dementia Lewy bodies (DLB) a Clinical Dementia Rating (CDR) score of ≤1.We examined 168 AD (126 CDR score=0.5, 42 score=1) 169 DLB (104 65 whose diagnoses were supported by 18F-flobetaben positron-emission tomography (PET) 18F-N-(3-fluoropropyl)-2β-carbon ethoxy-3β-(4-iodophenyl) nortropane PET. Neuropsychological test scores compared after controlling for age, sex,...
Patients with Alzheimer disease (AD) frequently suffer from various sleep disturbances. However, how disturbance is associated AD and its progression remains poorly investigated. We investigated the association of total time brain amyloid tau burden, cortical atrophy, cognitive dysfunction, their longitudinal changes in spectrum.In this retrospective cohort study, we enrolled participants on spectrum who were positive 18F-florbetaben (FBB) PET. All underwent Pittsburgh Sleep Quality Index,...
The co-occurrence of amyloid-β pathology in Parkinson's disease (PD) is common; however, the role deposition motor prognosis remains elusive. This study aimed to investigate association between striatal amyloid deposition, complications and patients with PD.
Down syndrome is likely to develop Alzheimer's disease (AD) at an extremely young age due overproduction of β-amyloid protein by the trisomy amyloid precursor gene on chromosome 21. We present a patient with showing excessive tau accumulation in diffuse neocortex 18F-AV-1451 positron emission tomography (PET) study. A was included for this For comparison, 15 early-onset AD patients (mean 61 years) and 20 healthy controls were included. All participants underwent PET 18F-florbetaben. Based...