A5089152622- Liver physiology and pathology
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Respiratory Support and Mechanisms
- Liver Disease Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Inhalation and Respiratory Drug Delivery
- Pancreatic and Hepatic Oncology Research
- Tracheal and airway disorders
- Optical Imaging and Spectroscopy Techniques
- Anesthesia and Sedative Agents
- Neonatal Respiratory Health Research
- Drug-Induced Hepatotoxicity and Protection
- Cancer Research and Treatments
- Organ Transplantation Techniques and Outcomes
- Pharmacogenetics and Drug Metabolism
- Virus-based gene therapy research
- Hepatocellular Carcinoma Treatment and Prognosis
- Drug Transport and Resistance Mechanisms
- T-cell and Retrovirus Studies
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Cancer, Hypoxia, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
Tokyo Metropolitan Police Hospital
2021-2025
Toho University
2024
Toho University Ohashi Medical Center
2024
Funabashi Municipal Medical Center
2022
The University of Tokyo
2010-2020
International University of Health and Welfare
2018-2020
University of Tokyo Hospital
2014-2018
Tokyo Women's Medical University
2011-2016
Chiba University Hospital
2013
Tokyo Women's Medical University Yachiyo Medical Center
2012
Isono, Shiroh, John E Remmers, Atsuko Tanaka, Yasuhide Sho, Jiro Sato, and Takashi Nishino. Anatomy of pharynx in patients with obstructive sleep apnea normal subjects. J. Appl. Physiol. 82(4): 1319–1326, 1997.—Anatomic abnormalities the are thought to play a role pathogenesis (OSA), but their contribution has never been conclusively proven. The present study tested this anatomic hypothesis by comparing mechanics paralyzed OSA According evaluation sleep-disordered breathing (SDB) nocturnal...
The purpose of this study was to evaluate whether model-based iterative reconstruction (MBIR) enables dose reduction over adaptive (ASIR) while maintaining diagnostic performance.In institutional review board-approved and Health Insurance Portability Accountability Act-compliant study, 59 patients (mean [SD] age, 64.7 [13.4] years) gave informed consent undergo reference-, low-, ultralow-dose chest computed tomography (CT) with 64-row multidetector CT. reference- low-dose CT involved the use...
Furosemide is known to influence the activity of vagally mediated mechanoreceptors in airways. Because vagal afferent fibers may play an important role modulation sensation dyspnea, it possible that inhaled furosemide modify dyspnea. In a double-blind, randomized, crossover study, we compared effect on dyspneic with placebo. Severe was induced 12 healthy subjects two ways: (1) breathholding and (2) loaded breathing combination inspiratory resistive load (240 cm H2O/L/s) hypercapnia by extra...
The placement of an endotracheal tube (ETT) may promote laryngeal swelling, which is important cause upper airway obstruction after extubation. authors hypothesized that swelling ETT increases resistance and tested hypothesis by comparing postoperative patency between patients with those a Laryngeal Mask Airway trade mark (LMA).Fourteen adult who underwent elective minor surgeries were randomly allocated to two groups whose would be managed through ETTs (the group) or LMAs LMA during the...
Recent studies suggest advantages of muscle relaxants for facemask ventilation. However, direct effects on mask ventilation remain unclear because these did not control mechanical factors influencing We tested a hypothesis that relaxants, either rocuronium or succinylcholine, improve ventilation.In anesthetized adult persons with normal upper airway anatomy, tidal volumes during were measured while maintaining the neutral head and mandible positions pressures ventilator before paralysis...
To evaluate dose reduction and image quality of abdominopelvic computed tomography (CT) reconstructed with model-based iterative reconstruction (MBIR) compared to adaptive statistical (ASIR).In this prospective study, 85 patients underwent referential-, low-, ultralow-dose unenhanced CT. Images were ASIR for low-dose (L-ASIR) CT (UL-ASIR), MBIR (UL-MBIR). Image noise was measured in the abdominal aorta iliopsoas muscle. Subjective analyses a lesion detection study (adrenal nodules) conducted...
Radiation therapy (RT) continues to play a central role as an effective therapeutic modality for variety of tumors and vascular malformations in the nervous system. Although planning delivery techniques RT have evolved substantially during past few decades, structures surrounding target lesion are inevitably exposed radiation. A wide radiation-induced changes may be observed at posttreatment imaging, which confusing when interpreting images. Histopathologically, radiation can deleterious...
Abstract Next‐generation sequencing ( NGS ) has been implemented in clinical oncology to analyze multiple genes and guide therapy. In patients with advanced lung cancer, small biopsies such as computed tomography‐guided needle biopsy CTNB ), endobronchial ultrasound‐guided transbronchial aspiration EBUS ‐ TBNA TBB are less invasive preferable resection make a pathological diagnosis. However, the quality of DNA / RNA from tumor samples is unknown. Between April 2017 March 2018, 107...
We have developed a technique for installing alveolar capsules in dogs with intact chest wall, by exposing region of parietal pleura between pair ribs and gluing the visceral together around small lung. This allows direct measurement pressure during spontaneous breathing. measured normal using this while suddenly interrupting flow at trachea passive expiration. Tracheal exhibited very rapid rise immediately on interruption that we showed to be composed two distinct roughly equal parts: one...
Chromosome studies were conducted on 15 patients with adult T-cell leukemia. Cells chromosomal abnormality seen in 14 of the patients. The modal chromosome number was near diploid range all most common 14q+ marker and partial deletion long arm 6, i.e., 6q-, which eight seven cases, respectively. Donor chromosomes involved varies, Yq, #5p, #5q, #9q, #10q or #12q, except for two whose donor origins unable to determine. break point band at q32. 6q- due a one patient interstitial six A 14q-...
To compare the differences in metal artefact degree and depiction of structures helical neck CT, patients with metallic dental fillings, among adaptive iterative dose reduction three dimensional (AIDR 3D), forward-projected model-based reconstruction solution (FIRST) AIDR 3D single-energy (SEMAR-A).In this retrospective clinical study, 22 (males, 13; females, 9; mean age, 64.6 ± 12.6 years) fillings who underwent contrast-enhanced CT involving oropharyngeal region were included. Neck axial...
Objective This study aimed to introduce and evaluate a novel software-based system, BioTrace, designed for real-time monitoring of thermal ablation tissue damage during image-guided radiofrequency hepatocellular carcinoma (HCC). Methods BioTrace utilizes proprietary algorithm analyze the temporo-spatial behavior gas bubble activity ablation, as seen in conventional B-mode ultrasound imaging. Its predictive accuracy was assessed by comparing zones it predicted with those annotated...