A5027177975- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- COVID-19 Clinical Research Studies
- Liver Disease and Transplantation
- Telemedicine and Telehealth Implementation
- Mobile Health and mHealth Applications
- Pancreatic and Hepatic Oncology Research
- COVID-19 and healthcare impacts
- Helicobacter pylori-related gastroenterology studies
- Liver Diseases and Immunity
- Long-Term Effects of COVID-19
- Autophagy in Disease and Therapy
- Adolescent Sexual and Reproductive Health
- Chronic Disease Management Strategies
- Vaccine Coverage and Hesitancy
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Pancreatitis Pathology and Treatment
- Inflammasome and immune disorders
- Proteoglycans and glycosaminoglycans research
- SARS-CoV-2 and COVID-19 Research
- Kawasaki Disease and Coronary Complications
- Gastric Cancer Management and Outcomes
Alexandria University
2019-2025
The study is aimed at evaluating knowledge, attitude, and barriers to telemedicine among the general population in Egypt.A questionnaire-based cross-sectional design was carried out Egyptian population. A convenience sampling method used approach eligible participants from University Teaching Hospitals of eight governorates May July 2020.A total 686 filled questionnaire (49.4% were males, mean age 36.7 ± 11.2 years old). Half stated that they previously a tool, mainly follow up laboratory...
Familial Mediterranean Fever (FMF) is a hereditary autosomal recessive disease which mainly seen in the Turks, Armenians, Arabs, and Jews. It characterized by recurrent episodes of fever, polyserositis, rash. MEFV gene, encoding pyrin protein, located on short arm chromosome 16. FMF associated with broad mutational spectrum this gene. Certain mutations are more common particular ethnic groups. To date, different were observed studies carried out regions worldwide. However, most these did not...
Incorporation of telemedicine in general clinical practice is becoming a compelling need nowadays the context COVID-19 pandemic and its consequent burdens on healthcare systems. Though appears to be appealing carries lot advantages, yet it still faced by many challenges barriers especially developing countries. Our aim was explore impression providers about applicability Egypt. A cross-sectional study conducted among from different Egyptian governorates through web-based survey. The survey...
Healthcare workers (HCWs) are still at higher risk of acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections than the general population. Identifying factors associated with SARS-CoV-2 is paramount importance to protect HCWs and non-infected patients attending different healthcare facilities.To recognize predictors for severity SARS-CoV2 infection among working in either COVID-19 or non-COVID-19 settings. Also, assess compliance HCW standard precautions control...
Introduction: In Egypt, there is a paucity of new data regarding awareness HIV/AIDS among physicians. This study aimed to assess the level awareness, attitude, practice, and knowledge sample Egyptian physicians HIV natural history, epidemiology, virology, method transmission, clinical manifestations, diagnosis, prevention, management. Methodology: Sixty-eight were enrolled in an observational analytic multicenter cross-sectional KAP tertiary health care facilities covering different...
Hepatitis C virus (HCV)-related decompensated cirrhosis is a severe life-threatening illness. The safety of direct-acting antivirals (DAAs) has opened gate hope for that subgroup patients who were previously contraindicated interferon therapy.We aimed at the investigation and efficacy different DAAs regimens in treatment HCV-related patients, to determine sustained virological response (SVR)12 rates analyze factors associated with response.A retrospective, single-center study including...
Abstract The continuous search for simple, noninvasive methods assessing liver fibrosis remains very important to help risk-stratify and follow-up patients with chronic hepatitis C virus (HCV). This study aimed evaluate the diagnostic performance accuracy of six serological scores assessment in comparison histopathology. retrospective cohort included data from 19501 HCV infection who had biopsies as an treatment prerequisite within Egyptian national program. Six (FIB-4, APRI, King’s score,...
Abstract The first direct-acting antiviral (DAA) medications were approved for the treatment of chronic hepatitis C virus (HCV) in 2011. Later, appearance novel DAAs had revolutionized landscape HCV whose early options limited to interferon (IFN) either alone or combinations. This review discusses paradigm shift legibility treating different groups patients with after introduction DAAs, along consequent changes guidelines. IFN-based therapy was firstly used HCV. Unfortunately, it exhibited...
To assess serum 25-hydroxyvitamin D3 level and insulin resistance (IR) in hepatitis B virus (HBV) patients compared with controls to evaluate the correlation HBV viral load, severity of liver disease degree fibrosis.A case-control study. Sixty 60 were enrolled. Chemiluminescence was used determine levels. Insulin evaluated using homeostasis model assessment method. Polymerase chain reaction quantify loads. Severity assessed by Child-Pugh scores. Transient elastography...
Abstract Background The most common primary liver cancer in adults is hepatocellular carcinoma (HCC) which commonly presented with a poor prognosis. Therefore, it important to explore effective biomarkers and therapeutic targets for HCC patients. Autophagy involved the development prevention of cancer. Mammalian Beclin-1 needed an autophagic vesicle HCC. Autophagy-related protein-5 (ATG5) molecule cell death during autophagy. objective investigate serum ATG 5 Beclin 1 levels HCV-induced...
Background Virus C infection is recently treated successfully with plenty of direct antiviral agents (DAAs). We aimed to evaluate the effect disease stage and treatment outcome on dynamics liver functions during hepatitis DAAs. Methods reported function in 2354 subjects diagnosed as chronic before, after different DAAs regimens. Patients were classified into two groups according response further subclassification presence or absence cirrhosis, changes compared each group subgroup. Results...
Objectives The objective of this study was to screen for significant hepatic fibrosis or steatosis in asymptomatic, apparently healthy subjects by using Vibration-controlled transient elastography and controlled attenuation parameter (CAP). Methods Prospectively, 433 asymptomatic adults were included. Fibroscan/CAP examination performed all them. Subjects with liver stiffness measurement > 6 kPa CAP >248 dB/m further evaluated assess underlying chronic disease. Results According...
CD44 has been demonstrated to play a pivotal role in regulating tumor cell progression, including hepatocellular carcinoma (HCC) development. Here, we aimed establish scoring system evaluate the risk of developing HCC utilizing CD44-rs187115 SNP polymorphism. A prospective cohort 120 individuals was enrolled four groups: 19 non-metastatic patients, 21 metastatic, 40 patients with hepatitis C-related cirrhosis, and controls. Allelic discrimination gene polymorphism assessed using TaqMan...
Background: Micro-ribonucleic acids (MiRNAs) are small, non-coding RNA molecules which regulate gene expression.Several miRNAs including miR-23a were found to be frequently deregulated in hepatocellular carcinoma (HCC).Objective: This study aimed evaluate serum as a biomarker of hepatitis C related HCC.Methods: was conducted on 60 virus (HCV) infected patients (group I: without cirrhosis, group II with cirrhosis and III HCV associated HCC) control 20 healthy volunteers.All submitted history...