A5012418051- Protein Hydrolysis and Bioactive Peptides
- Proteins in Food Systems
- Milk Quality and Mastitis in Dairy Cows
- Probiotics and Fermented Foods
- Animal Genetics and Reproduction
- Gut microbiota and health
- Infant Nutrition and Health
- Food and Agricultural Sciences
- Advanced Drug Delivery Systems
- Animal Diversity and Health Studies
- Microscopic Colitis
- Neuropeptides and Animal Physiology
- Transgenic Plants and Applications
- Microbial Metabolism and Applications
- Food Allergy and Anaphylaxis Research
- Meat and Animal Product Quality
- Genetic and phenotypic traits in livestock
- Digestive system and related health
- Celiac Disease Research and Management
Norwegian University of Life Sciences
2017-2025
Aarhus University
2017
This study focused on identifying amylase-trypsin inhibitors (ATIs) in seven Norwegian-cultivated wheat varieties, including common and ancestral species, potentially harmful opioid peptides within the ex vivo digesta of these wheats. LC–MS/MS analysis tryptic from ATI fractions revealed that variety Børsum exhibited highest diversity ATIs (n = 24), while they were less represented tetraploid emmer 11). Hexaploid Bastian showed low relative abundance ATIs. Nevertheless, digestion Mirakel by...
Safety is the most important criteria of any substance or microorganism applied in food industry. The whole-genome sequencing (WGS) an indigenous dairy isolate LL16 confirmed it to be Lactococcus lactis subsp. with genome size 2,589,406 bp, 35.4% GC content, 246 subsystems, and 1 plasmid (repUS4). Nextera XT library preparation kit was used generate DNA libraries, carried out on Illumina MiSeq platform. In silico analysis L. strain revealed non-pathogenicity absence genes involved...
We investigated the digestive peptide profiles of pea and faba bean proteins to evaluate possible bioactive peptides (BAPs), test immune-modulating properties selected using in vitro cell model. More than 400 unique were released upon gastrointestinal digestion identified by high-resolution mass spectrometry (HPLC-ESI-MS/MS). Among these, 24 potentially as predicted silico analysis. Also, up 275 recognized BAPs eight known allergens within sequences digests. Four significantly decreased IL-8...
This work aimed to study the opioid peptide β-casomorphin-7 (BCM7) degradation or stability during digestion using human gastrointestinal (GI) juices and porcine jejunal brush border membrane (BBM) peptidases. Synthetic BCM7 was subjected in vitro by GI fluids obtained from volunteers for 180 min, downstream with BBM vesicles. The sampled at 4 time points over 24 h after addition. digests were profiled HPLC-electrospray ionization mass spectrometry (ESI/MS) monitor digestion, intact through...
Six cattle breeds native to Norway, have for almost half a century been at risk of extinction. Due their small population sizes, they hardly improved by breeding many decades. Still, the endangered represent source genetic diversity with special milk qualities compared modern breed, Norwegian red (NRF). This study reports first time detailed overview composition. Milk from seven breeds, in total 200 individuals, were included study. Rare variants αs1-and αs2-casein, and β-casein A1 κ-casein...
Celiac disease (CeD) is an autoimmune enteropathy triggered by immunogenic gluten peptides released during the gastrointestinal digestion of wheat. Our aim was to identify T cell epitope-containing after ex vivo ancestral (einkorn, spelt and emmer) common (hexaploid) wheat (Fram, Bastian, Børsum Mirakel) using human juices. Wheat porridge digested a static model. Peptides 240 min were analyzed liquid chromatography coupled high-resolution mass spectrometry (HPLC-ESI MS/MS). Ex fewer from...
Six cattle breeds native to Norway, have for almost half a century been at risk of extinction. Due their small population sizes, they hardly improved by breeding many decades. Still, the endangered represent source genetic diversity with special milk qualities compared modern breed, Norwegian red (NRF). This study reports first time detailed overview composition. Milk from seven breeds, in total 200 individuals, were included study. Rare variants αs1- and αs2-casein, β-casein A1 κ-casein B...