A5059493656- Multiple Sclerosis Research Studies
- Ocular Diseases and Behçet’s Syndrome
- Peripheral Neuropathies and Disorders
- Autoimmune Neurological Disorders and Treatments
- Retinal and Optic Conditions
- Systemic Lupus Erythematosus Research
- Cerebral Venous Sinus Thrombosis
- Autoimmune and Inflammatory Disorders Research
- Polyomavirus and related diseases
- Systemic Sclerosis and Related Diseases
- Sphingolipid Metabolism and Signaling
- Migraine and Headache Studies
- Urinary Bladder and Prostate Research
- CNS Lymphoma Diagnosis and Treatment
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cerebrovascular and genetic disorders
- Pelvic floor disorders treatments
- Inflammasome and immune disorders
- Long-Term Effects of COVID-19
- Vasculitis and related conditions
- Cytokine Signaling Pathways and Interactions
- Neuroinflammation and Neurodegeneration Mechanisms
- Immunotherapy and Immune Responses
- RNA regulation and disease
- Protein Tyrosine Phosphatases
Istanbul University
2016-2025
Acıbadem University
2009-2023
Adli Tıp Kurumu
2022
Neurology, Inc
2020
Npistanbul Brain Hospital
2015
Istanbul Bilim University
2015
University of Illinois Urbana-Champaign
2008
University of Illinois Chicago
2008
University of Cambridge
2003
Addenbrooke's Hospital
2003
Background: Many studies on multiple sclerosis (MS) reveal different prevalence and epidemiologic results. Objectives: In this study, we aimed to determine the profile of MS using official health records in Turkey. Methods: Patients diagnosed with from data Ministry Health, representing entire population Turkey, were included study. Prevalence incidence calculations performed gender, age, year birth, city residence, diagnosis. Results: As a result number patients ICD code G35 was determined...
Anti-aquaporin-4 (Aqp-4) antibody and complement system have emerged as major pathogenic factors in neuromyelitis optica (NMO). To test the significance of interleukin-6 (IL-6), another important humoral immunity factor, NMO pathogenesis, we measured serum cerebrospinal fluid (CSF) IL-6 levels 23 NMO, 11 transverse myelitis, 16 optic neuritis, 27 relapsing remitting multiple sclerosis patients, 20 neurologically normal controls. myelitis patients had higher CSF than other groups....
Neurologic involvement in the pediatric population with Behçet disease (BD) is limited to case reports. The aim of this study examine frequency and type neurologic patients BD.Medical records 728 a diagnosis neuro-BD (NBD) 2 large BD cohorts followed Istanbul University were included study. Patients an onset both systemic symptoms at or before age 16 (pediatric neuro-BD) identified. Demographic clinical characteristics NBD compared adult NBD.There 26 cases (3.6%) 702 (96.4%) adult-onset...
The pathogenesis of idiopathic intracranial hypertension (IIH) is currently unknown and there are speculations about the contribution some immunologic factors. aim this study to investigate presence oligoclonal bands (OCBs) cerebrospinal fluid (CSF) and/or serum cytokine levels in patients with IIH.Patients fulfilling revised diagnostic criteria for IIH were included. Their demographic, clinical, ophthalmologic laboratory features examined. Serum CSF samples detected by isoelectric focusing...
Background : Thyroid antibodies (Thy-Abs) are frequently detected in various autoimmune disorders coexistence with other systemic autoantibodies. In association an encephalopathy, they often taken as evidence of Hashimoto's encephalitis (HE). However, the presence Thy-Abs a cohort limbic (LE) patients and their anti-neuronal autoimmunity has not been explored. Patients Methods We investigated thyroid sera 24 LE without identified tumors by cell-based assay radioimmunoassay evaluated clinical...
IntroductionGABAB-R encephalitis is a rare and newly recognized autoimmune disease. This study investigates the clinical laboratory features, treatment response, prognosis, malignancy associations in GABAB-R encephalitis.MethodsWe included consecutive patients with autoantibodies retrospectively analyzed their data, neuroimaging, EEG findings, seizure characteristics, responses, cancer presence. Prognosis was classified using final Modified Rankin Score (mRS), mRS>2 indicating poor...
GABAB-R encephalitis is a rare recognized autoimmune disease. This study investigates the clinical and laboratory features, treatment response, prognosis, malignancy associations in encephalitis. We included consecutive patients with autoantibodies retrospectively analyzed their data, neuroimaging, EEG findings, seizure characteristics, responses, cancer presence. Prognosis was classified using final Modified Rankin Score (mRS), mRS > 2 indicating poor prognosis. There were 17 antibodies (12...
Patients with the syndrome of headache neurological deficits and lymphocytosis (HaNDL) typically present recurrent temporary attacks symptoms cerebrospinal fluid lymphocytosis.To identify potential HaNDL-associated antibodies directed against neuronal surface and/or synapse antigens, sera four HaNDL patients controls were screened indirect immunohistochemistry, immunofluorescence, cell-based assay, radioimmunoassay, protein macroarray enzyme-linked immunosorbent assay (ELISA).Although did...
Uveitis is occasionally encountered in multiple sclerosis (MS) patients. The objective of this report to investigate whether uveitis has a prognostic impact on the clinical course MS. Several and demographic features were compared between 41 MS patients with 100 randomly selected without uveitis. While there no significant differences by means gender, age onset, oligoclonal band positivity disease duration, EDSS progression index (PI) scores significantly lower than those (p = 0.004 <0.001,...
<h3>SUMMARY:</h3> We report 2 patients with migraine aura, in whom SWI showed transient prominence of the venous vasculature within areas impaired perfusion. The findings resolved spontaneously both patients. This imaging technique may play a helpful role assessing vascular events aura.