A5004563169- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Cardiovascular and exercise physiology
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiomyopathy and Myosin Studies
- Mechanical Circulatory Support Devices
- Viral Infections and Immunology Research
- Congenital Heart Disease Studies
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrest and Resuscitation
- Pericarditis and Cardiac Tamponade
- Heart Failure Treatment and Management
- Aortic Disease and Treatment Approaches
- Pulmonary Hypertension Research and Treatments
- Parathyroid Disorders and Treatments
- Heart Rate Variability and Autonomic Control
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiac Health and Mental Health
- Coronary Artery Anomalies
- Transplantation: Methods and Outcomes
- Cardiovascular Disease and Adiposity
University of Siena
2018-2025
Azienda Ospedaliero-Universitaria Careggi
2017-2018
Although structured exercise training is strongly recommended in cardiac patients, uncertainties exist about the methods for determining intensity (EI) and their correspondence with effective EI obtained by ventilatory thresholds. We aimed to determine first (VT
AimsMyocardial work (MW) estimation by pressure-strain loops using speckle tracking echocardiography (STE) has shown to evaluate left ventricular (LV) contraction overcoming the load-dependency limit of LV global longitudinal strain (GLS). This proved useful hemodynamic variation settings e.g. heart failure and valvular disease. However, MW parameters across different stages primary mitral regurgitation (MR) its impact on symptoms, which was aim our study, never been investigated.Methods...
Sodium-glucose cotransporter 2 inhibitors were shown to reduce morbidity and mortality in patients with heart failure. This study aims assess potential effects of dapagliflozin nondiabetic failure reduced ejection fraction (HFrEF) mildly (HFmrEF) on cardiac function assessed by speckle tracking echocardiography (STE). randomized, prospective, single-center, open-label trial compared consecutive outpatients HFrEF or HFmrEF receiving treated optimal medical therapy (OMT) except sodium-glucose...
Right heart failure (RHF) after left ventricular assist device (LVAD) implant is burdened by high morbidity and mortality rates should be prevented appropriate patient selection. Adequate right function of paramount importance but its assessment complex cannot disregard afterload. Myocardial work (MW) a non-invasive Speckle Tracking Echocardiography-derived method to estimate pressure-volume loops. The aim this study was evaluate the performance myocardial predict RHF long-term LVAD...
Abstract Background Mitral regurgitation (MR) is the second most common valvular heart disease (VHD) in Europe, for which resolutive treatment surgical intervention. A careful preoperative evaluation of patients with MR important to optimize timing intervention and avoid possible complication after surgery. For this purpose, finding reliable prognostic markers predict adverse outcome mitral valve surgery may be fundamental. The aim study was assess parameters, among basic speckle tracking...
Abstract Background The diagnostic pathway of pulmonary hypertension (PH) is complex and requires several parameters. Differential diagnosis between left heart disease (group 2) 3) as PH etiology also challenging. latest European guidelines recommend a comprehensive echocardiographic evaluation for suspected PH, the use basic indices to assess cardiac PH. Speckle tracking echocardiography (STE) has emerged more sensitive technique evaluate myocardial performance in different clinical...
Abstract Aims Heart failure (HF) is a global health burden which prognostic assessment currently challenging. Speckle tracking left atrial strain widely recognized as predictor of HF outcome. Our aim was to systematically investigate the value peak longitudinal (PALS) in acute and chronic according ventricular (LV) function, age gender. Methods results A systematic literature search medical databases performed using PRISMA principles. All relevant studies reporting LA with reduced, mildly...
Accurate prognostic stratification in patients with chronic heart failure and reduced ejection fraction (HFrEF) remains a significant clinical challenge. Many different parameters, including left ventricular (LV) right (RV) function cardiopulmonary exercise testing (CPET) are available the literature. LV (LVEF) is most used parameter practice. This study aimed to analyze CPET echocardiographic data under evaluation for transplantation (HTx) identify that best correlates cardiac events....
The benefits of physical activity are well established, leading to both cardiovascular and non-cardiovascular benefits, improving quality life reducing mortality. Despite such striking body evidence, patients with hypertrophic cardiomyopathy often discouraged by health professionals practice personalised exercise prescription is an exception rather than the rule. As a result, on average less active spend significantly time at work or recreational general population. Exercise restriction...
Endurance sports practice has significantly increased over the last decades, with a growing proportion of master athletes. However, concerns exist regarding potential proarrhythmic effects induced by ultra-endurance sports. This study aimed to analyse acute an ultramarathon race on atrial remodelling and supraventricular arrhythmias in population athletes.Master athletes participating (50 km, 600 m elevation gain) no history heart disease were recruited. A single-lead ECG was recorded...
Abstract Aims To develop and validate equations predicting heart rate (HR) at the first second ventilatory thresholds (VTs) an optimized range-adjusted prescription for patients with cardiometabolic disease (CMD). compare their performance against guideline-based exercise intensity domains. Methods results Cross-sectional study involving 2868 CMD from nine countries. HR predictive VTs (VT1, VT2) were developed using multivariate linear regression 975 cycle-ergometer cardiopulmonary tests...
The non-ischaemic left ventricular scar (NILVS) is an emerging substrate of arrhythmias (VA) in the athlete. We tested diagnostic value VA reproducibility at repeated exercise testing (ET).We included consecutive athletes who underwent cardiac magnetic resonance (CMR) for evaluation and two ET off-therapy within 12 months. Those with a positive family history premature sudden death/cardiomyopathy, syncope/pre-syncope, ECG or echocardiography abnormalities, low-risk (exercise-suppressed...
Advanced heart failure (AdHF) is characterized by variable degrees of left ventricular (LV) dysfunction, myocardial fibrosis, and raised filling pressures which lead to atrial (LA) dilatation cavity dysfunction. This study investigated the relationship between LA peak longitudinal strain (PALS), assessed speckle-tracking echocardiography (STE), invasive measures LV fibrosis in a group AdHF patients undergoing transplantation (HTX).
Background SARS-CoV-2 infection might be associated with cardiac complications in low-risk populations, such as competitive athletes. However, data obtained adults cannot directly transferred to preadolescents and adolescents who are less susceptible adverse clinical outcomes often asymptomatic. Objectives We conducted this prospective multicentre study describe the incidence of cardiovascular following a large cohort junior athletes examine effectiveness screening protocol for safe return...