- Pain Management and Opioid Use
- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Opioid Use Disorder Treatment
- Pediatric Pain Management Techniques
- Patient-Provider Communication in Healthcare
- Intensive Care Unit Cognitive Disorders
- Pharmacological Effects and Toxicity Studies
- Childhood Cancer Survivors' Quality of Life
- Anesthesia and Pain Management
- Cancer Treatment and Pharmacology
- Empathy and Medical Education
- Family and Patient Care in Intensive Care Units
- Cardiac Structural Anomalies and Repair
- Management of metastatic bone disease
- Mechanical Circulatory Support Devices
- AI in cancer detection
- Cardiovascular Function and Risk Factors
- Peptidase Inhibition and Analysis
- Cardiac Valve Diseases and Treatments
- Retinal Development and Disorders
- Cancer Genomics and Diagnostics
- Myofascial pain diagnosis and treatment
- Cloud Data Security Solutions
- Liver Disease Diagnosis and Treatment
The University of Texas MD Anderson Cancer Center
2016-2025
Nottingham University Hospitals NHS Trust
2024
Shaheed Mohtarma Benazir Bhutto Medical University
2024
Chandka Medical College
2024
Rice University
2024
Nishtar Medical College and Hospital
2023-2024
National Institute for Implementation Research on Non-Communicable Diseases
2024
Yeshiva University
2024
Aga Khan University Hospital Nairobi
2024
Aga Khan University Hospital
2024
In the United States, opioid regulations have become increasingly stringent in recent years. Increased regulatory scrutiny, part, is related to heightened awareness through literature and a media blitz on prescription epidemic. These potential impact trends by health care providers. Our objective was evaluate changes type dose of prescriptions among patients who are referred oncologists an outpatient palliative clinic.We reviewed electronic records 750 were seen as new consultations at MD...
Abstract Background Few studies examine how patients with advanced cancer cope stress. The objective of our study was to evaluate coping strategies adopted by and their relationship symptom burden. Methods A secondary data analysis a prospective cross-sectional survey tobacco use conducted, which examined demographics, burden (Edmonton Symptom Assessment System), (the Brief COPE Questionnaire). Demographic characteristics were summarized standard summary statistics; we also associations...
An analytical benchmark for high-sensitivity cardiac troponin (hs-cTn) assays is to achieve a coefficient of variation (CV) ≤ 10.0 % at the 99th percentile upper reference limit (URL) used diagnosis myocardial infarction. Few prospective multicenter studies have evaluated assay imprecision and none determined precision female URL which lower than male all assays. Human serum plasma matrix samples were constructed yield hs-cTn concentrations near URLs Abbott, Beckman, Roche, Siemens These...
Aberrant opioid use is a public health issue, which has not been adequately described in the palliative care literature. With increasing integration of into oncologic care, clinicians are seeing patients earlier disease trajectory, and therefore, more outpatients with chronic pain requiring therapy. This may have resulted concomitant rise number aberrant use. In this article, we report on two opioid-related behavior seen at our clinic. A high suspicion abuse, misuse, or diversion based...
PURPOSE Increasing opioid regulations have resulted in reduced prescriptions, including for cancer pain, despite guideline exemptions. Data after 2017 following the Centers Disease Control's 2016 pain management guidelines are limited on prescribing practices of oncologists. The purpose this study was to examine trend dose opioids prescribed by oncologists patients with referred outpatient palliative care between and 2021. METHODS A single-center, cross-sectional, retrospective conducted at...
The systematic inability of the Pakistani legal system to meet demands marginalized people is examined in this study utilizing a Critical Legal Studies framework, with particular emphasis on judiciary and legislation. It investigates experiences several groups, such as socioeconomic, gender, religious, ethnic minorities, using qualitative case methodology. According research, main causes inequality are discriminatory laws, judicial bias, obstacles obtaining justice. draws attention flaws...
BACKGROUND Transdermal fentanyl (TDF) is 1 of the most common opioids prescribed to patients with cancer. However, accurate opioid rotation ratio (ORR) from other TDF unknown, and various currently used methods result in wide variation ORR. The objective this study was determine ORR oral morphine equivalent daily dose (MEDD) when correcting for MEDD breakthrough (the net MEDD) cancer outpatients. METHODS records 6790 consecutive were reviewed at authors' supportive care center 2010 2013...
ContextThe optimal dose of fentanyl sublingual spray (FSS) for exertional dyspnea has not been determined.ObjectivesWe examined the effect two doses prophylactic FSS on dyspnea.MethodsIn this parallel, dose-finding, double-blind randomized clinical trial, opioid-tolerant cancer patients completed a shuttle walk test at baseline. Patients second 10 minutes after single equivalent to either 35%–45% (high dose) or 15%–25% (low total daily opioid dose. The primary outcome was change in modified...
Post-cardiac injury syndrome (PCIS) is an umbrella term used for the post-pericardiotomy syndrome, post-myocardial infarction (MI) related pericarditis (Dressler syndrome), and post-traumatic (percutaneous coronary intervention (PCI) or cardiac implantable electronic device (CIED) placement). All these conditions give rise to PCIS due inciting pericardial pleural mesothelial cells, leading subsequent inflammation syndromes ranging from uncomplicated massive effusion. We did a literature...
Regulation of biological processes occurs through complex, synergistic mechanisms. In this study, we discovered the orchestration multiple mechanisms regulating normal and diseased state (age related macular degeneration, AMD) in retina. We uncovered gene networks with overlapping feedback loops that are modulated by nuclear hormone receptors (NHR), miRNAs, epigenetic factors. utilized a comprehensive filtering pathway analysis strategy comparing miRNA microarray data between three mouse...
Establishing care preferences and selecting a prepared medical decision-maker (MDM) are basic components of advance planning (ACP) integral to treatment planning. Systematic ACP in the cancer setting is uncommon. We evaluated systematic social work (SW)-driven process for patient selection MDM.We used pre/post design, centered on SW counseling incorporated into standard-of-care practice. New patients with gynecologic malignancies were eligible if they had an available family caregiver or...
Background There is limited information regarding the true frequency of nonmedical opioid use (NMOU) among patients receiving therapy for cancer pain. Data to guide patient selection urine drug testing (UDT) as well timing and ordering UDT are insufficient. This study examined abnormal with who underwent random their characteristics. Methods Demographic clinical were retrospectively reviewed compared a historical cohort that targeted UDT. Random was ordered regardless patient's risk...
Background: The opioid rotation ratios (ORRs) and conversion (CRs) used worldwide among palliative care (PC) professionals to perform rotations (ORs) route conversions may have a wide variation. Methods: We surveyed PC on through email the Multinational Association of Supportive Care in Cancer's study group Twitter Facebook posts between September November 2020. Results: received 370 responses from respondents 53 countries: 276 (76%) were physicians, 46 (13%) advanced practice providers, 39...
This randomized controlled crossover study compares patients' perception of physicians' compassion and communication skills professionalism overall physician preference after watching two standardized scripted-video vignettes physicians.
Abstract Background There is limited evidence about the response of breakthrough pain (BTP) to most commonly used oral immediate-release (IR) opioids. Our aim was determine rate IR opioids for BTP control in patients with advanced cancer. Materials and Methods In this prospective study, palliative care outpatients, cancer adequately managed background pain, were asked complete a self-administered survey. We assessed patients’ baseline demographics, characteristics, alcoholism (CAGE...