A5067210117- RNA Research and Splicing
- Cardiomyopathy and Myosin Studies
- Mitochondrial Function and Pathology
- Pharmacological Effects and Toxicity Studies
- Viral Infections and Immunology Research
- Genetic Neurodegenerative Diseases
- Nuclear Structure and Function
- Endoplasmic Reticulum Stress and Disease
- Dementia and Cognitive Impairment Research
- Systemic Lupus Erythematosus Research
- Genomics and Chromatin Dynamics
- Neurogenetic and Muscular Disorders Research
- Cytomegalovirus and herpesvirus research
- Autism Spectrum Disorder Research
- Neurological Complications and Syndromes
- Intensive Care Unit Cognitive Disorders
- Neuroscience and Neuropharmacology Research
- Cardiovascular Effects of Exercise
- DNA Repair Mechanisms
- Alzheimer's disease research and treatments
Seattle Photonics Associates (United States)
2024-2025
University of New Mexico
2018-2019
Oregon Health & Science University
2001-2002
Medford Radiology Group
2002
Hennepin County Medical Center
2001
The identification of many medications that delay neurodegeneration in animal models has created too combinations to try patients when time is short. We hypothesized biomarkers premature neuronal aging are part the amyloid-tau-neurodegeneration (ATN) profile, namely amyloid-β ratio, phosphorylated tau 181 (pTau181), and neurofilament light chain (NfL), could provide tools optimize treatment single-patient trials rapidly. retrospectively analyzed these with extensive neuropsychiatric...
Abstract Idiopathic dilated cardiomyopathy (IDC), a treatable condition characterized by left ventricular dilatation and systolic dysfunction of unknown cause, has only recently been recognized to have genetic etiologies. Although familial (FDC) was thought be infrequent, it is now believed that 30‐50% cases IDC may familial. Echocardiographic electrocardiographic (ECG) screening first‐degree relatives individuals with FDC indicated because detection treatment are possible prior the onset...
Background. It has been suggested that cytomegalovirus infection increases the risk of ischemic heart disease. Both and disease are common after renal transplantation, suggesting a possible causal association in this population. Methods Patients. We studied 1004 consecutive transplants with no prior history grafts functioned at least 12 months. performed univariate multivariate analyses to examine effect other factors (measured during first posttransplant year) on development primary events...
A combinatorial explosion of agents that delay neurodegeneration in animal models has created a crisis abundance human applications with too many combinations to try when time is short. Plasma biomarkers premature neuronal aging, the amyloid-tau-neurodegeneration (ATN) profile, may provide tool rapidly optimize treatment single-patient trials. We retrospectively analyzed plasma ATN profiles patients extensive neuropsychiatric polypharmacy and aging. were based on amyloid-β ratio,...
Abstract Chart review of initial N=73 cohort screening for dementia risk revealed expected positive control with age across standard ATN measures. All measures were independent insulin sensitivity (insulin/BMI) Amyloid ratio was uncorrelated ptau181/Nfl. Broad chart a divergence between amyloid and tau serum markers: associates opioid use (r. 259, p. 01) increased fecundity 215, 079) while adverse decreased -0.223, p.067) absent statistical association use. This data is consistent previous...