A5009218233- Visual perception and processing mechanisms
- Glaucoma and retinal disorders
- Retinal Development and Disorders
- Ophthalmology and Visual Impairment Studies
- Retinal Imaging and Analysis
- Neural dynamics and brain function
- Visual Attention and Saliency Detection
- Face Recognition and Perception
- Drug-Induced Ocular Toxicity
- Mitochondrial Function and Pathology
Wellcome Centre for Human Neuroimaging
2022-2025
University College London
2018-2025
Institute of Ophthalmology
2025
Simulations of visual impairment are used to educate and inform the public. However, evidence regarding their accuracy remains lacking. Here we evaluated effectiveness modern digital technologies simulate everyday difficulties caused by glaucoma. 23 normally sighted adults performed two tasks that glaucoma patients often report with: a search task in which participants attempted locate mobile phone virtual domestic environments (virtual reality (VR)), mobility navigated physical, room-scale...
Peripheral vision is crucial for daily activities and quality of life, yet traditional measures visual function like acuity primarily assess central vision. Visual field tests can evaluate peripheral but require extended focus combined with precise fixation, often very challenging patients severe sight loss. Functional MRI (fMRI) population receptive (pRF) mapping offers a non-invasive way to map scotomas limited by its reliance on single contrast levels the necessity accurate fixation.We...
Peripheral vision is crucial for daily activities and quality of life, yet traditional measures visual function like acuity primarily assess central vision. Visual field tests can evaluate peripheral but require extended focus combined with precise fixation, often very challenging patients severe sight loss. Functional MRI (fMRI) population receptive (pRF) mapping offers a non-invasive way to map scotomas limited by its reliance on single contrast levels the necessity accurate fixation.We...
In instances of asymmetric peripheral vision loss (e.g., glaucoma), binocular performance on simple psychophysical tasks static threshold perimetry) is well-predicted by the better seeing eye alone. This suggests that largely 'better-eye limited'. present study, we examine whether this also holds true for real-world tasks, or even a degraded fellow contributes important information daily living. Twelve normally-sighted adults performed an everyday visually-guided action (finding mobile...
Face recognition is widely considered to be "special", involving dedicated brain regions with unique patterns of selectivity. This contrasts increasing evidence for common 'visuospatial coding', where even high-level category-selective areas share the spatial properties earlier regions. Here we examined whether retinotopic face-selective vary around visual field in a similar fashion those early cortex, and these could explain variations face perception field. We carried out mapping (V1-V3)...
Abstract Peripheral vision is crucial for daily activities and quality of life, yet traditional measures visual function like acuity primarily assess central vision. Visual field tests can evaluate peripheral but require extended focus combined with precise fixation, often very challenging patients severe sight loss. Functional MRI (fMRI) population receptive (pRF) mapping offers a non-invasive way to map scotomas limited by its reliance on single contrast levels the necessity accurate...
Many common blinding diseases, such as Glaucoma, begin in one eye. Being able to measure how asymmetric vision loss affects people's performance on everyday tasks may help identify pathologies early, and could provide an important endpoint when evaluating new therapies. Here, we report a series of studies which used virtual reality evaluate simulated, vision-loss affected response-speed visual search tasks. In Experiment I, six healthy adults (25.8 ± 3.8 years old) performed...