G. Friedman

ORCID: 0000-0003-3362-2562
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About
Contact & Profiles
Research Areas
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Lipid metabolism and disorders
  • Fatty Acid Research and Health
  • Diabetes and associated disorders
  • Lipid metabolism and biosynthesis
  • Immune Response and Inflammation
  • Vasculitis and related conditions
  • Adipose Tissue and Metabolism
  • Otitis Media and Relapsing Polychondritis
  • Immune Cell Function and Interaction
  • Cholesterol and Lipid Metabolism
  • Cancer, Lipids, and Metabolism
  • Lipoproteins and Cardiovascular Health
  • Vitamin C and Antioxidants Research
  • Adipokines, Inflammation, and Metabolic Diseases
  • Diabetes Management and Research
  • Atherosclerosis and Cardiovascular Diseases
  • Monoclonal and Polyclonal Antibodies Research
  • Cancer, Hypoxia, and Metabolism
  • Metabolism, Diabetes, and Cancer
  • Hormonal and reproductive studies
  • Autoimmune Bullous Skin Diseases
  • Influenza Virus Research Studies
  • Liver Disease Diagnosis and Treatment
  • Urticaria and Related Conditions

Seattle Pacific University
2025

Drexel University
2017

University of Michigan
2015

University of Pittsburgh
2015

Providence Hospital
2015

University College London
2015

Alzheimer’s Disease Neuroimaging Initiative
2015

Brigham and Women's Hospital
2015

Ixico (United Kingdom)
2015

Pfizer (United Kingdom)
2015

<b><i>Objective:</i></b> To determine the ability of apolipoprotein E (<i>APOE</i>) genotypes to predict days unconsciousness and a suboptimal functional outcome in traumatic brain injury (TBI) survivors. <b><i>Background:</i></b> TBI is known be associated with neuropsychological deficits disability. Recent evidence indicates that <i>APOE</i> plays pivotal role CNS response injury. <b><i>Methods:</i></b> In this prospective study authors determined tested their after at least 6 months 69...

10.1212/wnl.52.2.244 article EN Neurology 1999-01-01

Previous results have demonstrated that liver membranes possess two distinct lipoprotein receptors: a low density (LDL) receptor binds lipoproteins containing either apolipoprotein (apo-) B or apo-E, and an apo-E-specific apo-Econtaining lipoproteins, but not the apo-B-containing LDL.This study reports isolation purification of apo-B,E(LDL) apo-E receptors from canine human membranes.The were solubilized with zwitterionic detergent 3 -[ (3...

10.1016/s0021-9258(17)35655-7 article EN cc-by Journal of Biological Chemistry 1986-03-01

10.1016/0005-2760(76)90010-2 article EN Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1976-12-01

This study investigated whether parental socialization of negative emotions moderated the relationship between adolescents’ low executive function or high impulsivity and their current subsequent emotion dysregulation. Emotion dysregulation, characterized by difficulties in managing intensity duration emotions, is a transdiagnostic factor linked to adverse outcomes. Youth with poor functioning and/or are at risk for dysregulation; however, role parenting influencing this trajectory warrants...

10.1177/00332941241312315 article EN Psychological Reports 2025-01-04

Objectives. Hyperhomocysteinemia as well insulin resistance are considered to be risk factors for the development of coronary artery disease. This study was aimed at determining whether any relationship between plasma and glucose levels total homocysteine (tHcy) concentrations exists in a population based survey performed 10 years apart. Design Setting. A cross‐sectional undertaken during 1986–87 examine diabetes disease (CAD) Jewish Jerusalem. Ten later two groups individuals were invited...

10.1046/j.1365-2796.2000.00592.x article EN Journal of Internal Medicine 2000-02-01

In this investigation in cultured human fibroblasts, an attempt was made to determine the optimal metabolism of apolipoprotein (apo) B-100 lipoproteins from normolipidemic subjects. We supplemented culture systems containing 125I-lipoproteins with exogenous recombinant or plasmatic apo E-3. Very low density lipoprotein (VLDL) fractions I, II, and III, (LDL) were prepared one E 4/3 four 3/3 Without added E-3, cellular (binding, cell association, degradation) VLDL-I, III negligible. Exogenous...

10.1161/01.atv.8.5.480 article EN Arteriosclerosis An Official Journal of the American Heart Association Inc 1988-09-01

10.1016/0005-2760(81)90100-4 article EN Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1981-10-01

Onychomycosis is a fungal infection of the nail unit, and most common disorders. Current therapies for onychomycosis have less than ideal efficacy potential adverse effects. As previous studies shown that nonthermal plasma inhibits in vitro growth Trichophyton rubrum, we conducted pilot study on 19 participants with toenail onychomycosis. The primary endpoint was safety device, secondary outcome measures were clinical mycological cure. Patient satisfaction measured using questionnaires at...

10.1111/ced.12973 article EN Clinical and Experimental Dermatology 2017-02-11

Abstract Background. Dehydroepiandrosterone (DHEA) is a native steroid with an immunomodulating activity that was suggested to counterregulate some phenomena of immunosenescence. Recently, it shown reverse the age-associated decline immune response against influenza vaccine in aged mice. The present study designed evaluate effect DHEA on immunization elderly volunteers influenza. Methods. Seventy-one age 61–89 yr were enrolled prospective randomized, double-blind receive either (50 mg qd...

10.1210/jcem.82.9.4256 article EN The Journal of Clinical Endocrinology & Metabolism 1997-09-01

10.1016/0005-2760(78)90146-7 article EN Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1978-11-01

Intramuscular (IM) influenza vaccines are about 50% effective in preventing clinical illness among the elderly and their effectiveness eliciting mucosal response may be even lower. The aim of present study was to evaluate immunological effect a novel inactivated intranasal (IN) trivalent whole virus vaccine community-dwelling elderly. Sixty-one subjects were vaccinated with two doses an IN control group 31 commercial IM vaccine. Viral strains 1997/8 used A/Nanchang/933/95(H3N2),...

10.1002/(sici)1096-9071(200005)61:1<100::aid-jmv16>3.0.co;2-5 article EN Journal of Medical Virology 2000-05-01
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