- Molecular Biology Techniques and Applications
- Forensic and Genetic Research
- Environmental DNA in Biodiversity Studies
- Biosensors and Analytical Detection
- Epigenetics and DNA Methylation
- RNA Research and Splicing
- RNA regulation and disease
- Genomic variations and chromosomal abnormalities
- Graphene research and applications
- Medical Image Segmentation Techniques
- Spinal Cord Injury Research
- Advanced biosensing and bioanalysis techniques
- Gene expression and cancer classification
- Cancer-related molecular mechanisms research
- Wireless Signal Modulation Classification
- 2D Materials and Applications
- Circular RNAs in diseases
- Pharmacogenetics and Drug Metabolism
- Genomics and Phylogenetic Studies
- Nuclear materials and radiation effects
- SARS-CoV-2 detection and testing
- Cardiac electrophysiology and arrhythmias
- Digital Imaging for Blood Diseases
- Ion channel regulation and function
- Boron and Carbon Nanomaterials Research
Suzhou Institute of Biomedical Engineering and Technology
2023-2025
Chinese Academy of Sciences
2023-2025
Shanxi Medical University
2018-2025
China Rehabilitation Research Center
2025
Chinese Institute for Brain Research
2025
Gannan Medical University
2024-2025
Capital Medical University
2025
Sun Yat-sen University Cancer Center
2023
Chengdu University of Technology
2019-2023
Universidad del Noreste
2023
At present, the planning of 15-minute community-life circle is being actively promoted in China. Taking Baoding City as an example, status quo service facilities layout was analyzed based on POI data. Using spatial accessibility algorithm, ranges life more than 1000 communities were determined. By calculating up-to-standard rates public each district, it found that allocation medical and commercial urban community relatively perfect, but cultural pension obviously inadequate. Based this,...
Abstract Age prediction is of great importance for criminal investigation and judicial expertise. DNA methylation status considered a promising method to infer tissue age by virtue age‐dependent changes on sites. In recent years, forensic scientists have established various models predict the chronological blood, saliva, semen based status. However, hair‐inferred has not been studied in field science. this study, we measured statuses potential age‐related CpG sites using multiplex SNaPshot...
Abstract Background Observational studies have shown an association between cerebrospinal fluid (CSF) metabolites and low back pain (LBP), but the causal relationship these factors remains unclear. Methods We performed a two-sample Mendelian randomization (MR) analysis to examine whether there is CSF LBP. applied several MR methods, including inverse variance weighting, weighted median, MR-Egger, Wald ratio, MR-PRESSO, test conducted sensitivity assess robustness of results. Results...
ABSTRACT The detection of body fluids in biological stains at crime scenes and their association with donors is increasingly important for the validity evidence case investigations prosecutions. While autosomal short tandem repeats (STR) DNA methylation markers can effectively analyze personal identification fluid origin, there currently no integrated system simultaneous STR typing (subsource level) biofluid (source level). This study has developed a codetection based on...
Unbalanced and degraded mixtures (UDM) are frequently encountered during forensic DNA analysis. For example, units regularly encounter mixture signal where the from alleged offender is masked or swamped by high quantities of victim. Our previous data presented a new kind markers that composed deletion/insertion polymorphism (DIP) SNP we termed this microhaplotypes DIP-SNP (combination DIP SNP). Since such could be designed short enough for amplification, hypothesized applicable typing UDM....
Abstract In the past decades, messenger RNA (mRNA) biomarkers have been employed to identify origin of body fluids in forensic medicine. We hypothesized that polymorphism mRNA could be applied individuals mixture samples composed two fluids. this study, we selected five blood‐specific venous blood (SPTB, CD3G, AMICA1, ANK1, and GYPA) encompass 16 SNPs contributor(s). Five specific gene markers for menstrual blood, semen, skin, saliva, vaginal secretions were amplified typed as body‐fluid...
Complement is an important innate immune defence machinery. Once dysregulated, it often linked to pathogenesis of diverse autoimmune diseases. Artesunate (ART) a well-known anti-malarial compound. Recently, ART has been highlighted by its potential therapeutic effects on certain complement-related However, the underlying mechanisms are hitherto unknown. In present study, we found that mediated complement interception as validated analysis haemolytic assay. cell-based setup using dying Jurkat...
Delineating the lesion area is an important task in image-based diagnosis. Pixel-wise classification a popular approach to segmenting region of interest. However, at fuzzy boundaries, such methods usually result glitches, discontinuity or disconnection, inconsistent with fact that lesions are solid and smooth. To overcome these problems provide efficient, accurate, robust concise solution simplifies whole segmentation pipeline AI-assisted applications, we propose BézierSeg model which...