A5082979865- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Inflammasome and immune disorders
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Neuroendocrine Tumor Research Advances
- Diagnosis and treatment of tuberculosis
- Neonatal Health and Biochemistry
- Veterinary medicine and infectious diseases
- Liver Disease Diagnosis and Treatment
- Renal Diseases and Glomerulopathies
- Diverticular Disease and Complications
- Gastrointestinal disorders and treatments
- Hepatitis C virus research
- Nausea and vomiting management
- Pediatric Hepatobiliary Diseases and Treatments
- Streptococcal Infections and Treatments
- Metabolism and Genetic Disorders
- Microscopic Colitis
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Pancreatic and Hepatic Oncology Research
- IL-33, ST2, and ILC Pathways
- Hormonal Regulation and Hypertension
- Genetic and Kidney Cyst Diseases
Anadolu University
2024
Konya Eğitim ve Araştırma Hastanesi
2015-2018
Education and Research Institute
2015
Military Medical Academy
2000-2012
Maltepe University
2011-2012
Naval Academy
1996-2010
Turkcell (Turkey)
2010
Selçuk University
1991-2007
GATA Haydarpaşa Eğitim Hastanesi
2003-2007
Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi
2006
ObjectiveThe purpose of this trial was to determine the spectrum diseases with fever unknown origin (FUO) in Turkey.MethodsA prospective multicenter study 154 patients FUO twelve Turkish tertiary-care hospitals conducted.ResultsThe mean age 42 ± 17 years (range 17–75). Fifty-three (34.4%) had infectious (ID), 47 (30.5%) non-infectious inflammatory (NIID), 22 (14.3%) malignant (MD), and eight (5.2%) miscellaneous (Mi). In 24 (15.6%) cases, reason for high could not be determined despite...
To study the effect of continuous ambulatory peritoneal dialysis on nucleoside levels and clinical course in a patient with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). Patient We studied genetically verified MNGIE, who prior to treatment had lost weight progressively, developed amenorrhea, vomited multiple times daily, abdominal pain. Intervention The was treated for 3 years, symptoms plasma concentrations thymidine deoxyuridine were monitored.Dialysis stopped vomiting...
Leptin, a recently discovered protein, acts as hormonal feedback signal in regulating adipose tissue mass via hypothalamic mechanisms. Inflammatory bowel disease is often associated with anorexia and weight loss. The aim of the present study was to investigate serum leptin levels during time course acute phase ulcerative colitis (UC) evaluate whether leads bodyweight loss these patients.Serum 29 male patients UC 17 healthy controls similar age, sex body index (BMI) were measured. Erythrocyte...
Dental plaque is considered by some to be a secondary reservoir for Helicobacter pylori and thus responsible gastric reinfection. The aim of this study was investigate whether testing dental using rapid urease test (CLOtest) can used determine H. status.We investigated colonization its correlation with infection in 75 dyspeptic patients. CLOtest positivity.Tests were positive samples from 68 patients stomach 65 sensitivity status 89.7%, diagnostic accuracy 86.7%. Gastric eradication achieved...
Abstract Background and Aim: Many studies have reported poor results with standard first‐line treatment for Helicobacter pylori . Second‐line regimens that may overcome bacterial resistance can minimize side‐effects optimize compliance. The aim of this study was to evaluate the efficacy proton pump inhibitor (PPI) bismuth subcitrate‐based quadruple therapy, after failure a PPI plus clarithromycin amoxicillin as therapy. Methods: Patients who failed eradicate infection initial therapy were...
Use of mucolytic agents that result in reduced mucous viscosity the gastric has been suggested to have an additive effect curing Helicobacter pylori infection.Seventy Hpylori-positive patients were given either eradication treatment consisting 500 mg clarithromycin bid and 30 lansoprazole for 10 days plus mL (400 mg) N-acetyl cysteine (NAC) liquid tid (AC group) or only (control group). The results compared 1 month after completion treatment.Fifty-eight available statistical analysis. Of 28...
Benign recurrent intrahepatic cholestasis (BRIC) is a rare autosomal recessive or sporadic disorder, characterized by episodes of intense pruritus and jaundice that resolve spontaneously without leaving considerable liver damage. The attacks can start at any age, but the first attack usually seen before second decade life. We report case young adult male patient with BRIC who presented cholestatic negative work up for all possible etiologies biopsy consistent cholestasis. He improved on...
CagA seropositivity is closely associated with that of vacuolating cytotoxin (VacA). Helicobacter pylori strains positive for both VacA and were reported to be strongly peptic ulcer disease. Different results reporting cagA gene not more serious diseases, lowers the importance protein as a marker. In this study, examined in Turkish nonulcer dyspepsia patients; histopathologic scores (+) (-) groups compared.Sixty consecutive patients (one gastric ulcer, 13 duodenal 46 dyspepsia) (mean age...
abstract Background. N‐acetyl cystein, a mucolytic agent, might make Helicobacter pylori antigens shed more easily to stool, and therefore contribute the diagnostic accuracy of stool antigen test. The aim this study is investigate if cystein contributes test by increasing sensitivity specificity Materials Methods. 107 patients were separated into treatment placebo groups. AC group (n = 53) was given 5 ml acetyl (4%) t.i.d. Placebo 54) placebo, for 3 days. status determined both histology...
We assessed the diagnostic value of 14 C urea breath test (UBT) in detection Helicobacter pylori compared with histology and rapid urease (RUT). The study included 68 patients (22 men 46 women) dyspeptic symptoms. H. status was evaluated by UBT, RUT histology. Sensitivity, specificity, positive negative predictive values, accuracy were determined for UBT RUT. Histology revealed dense yeast-like micro-organisms biopsy specimens all false-positive results (n = 8), a significantly higher...
Studies performed on mice suggest that adropin is a peptide hormone playing role in metabolic homeostasis and prevention of obesity-associated insulin resistance. Our study was conducted to investigate the children with obesity or syndrome. The group consisted 70 patients, including 42 obese 28 syndrome, 26 healthy volunteers. After anthropometric variables blood pressure all participants were measured, serum lipids analyzed, liver USG oral glucose tolerance test performed, HOMA-IR values...
Idiopathic slow-transit constipation (STC) has been suggested to be a pangastrointestinal motility disorder. We investigated scintigraphically whether in the gallbladder and stomach was impaired constipation.Twenty-four patients with STC were studied. Colon transit time, motility, solid-phase gastric emptying measured by scintigraphy.Gallbladder dysmotility observed 8 of 18 (44.4%) patients. Mean ejection fraction 41.6 +/- 13.6% (range, 16.3-67.0%). Gastric delayed 9 (50%) half-emptying time...
It is being questioned if Helicobacter pylori infection, which causes a chronic inflammatory response, can increase the frequency and severity of attacks in patients with Familial Mediterranean Fever (FMF) impact response be diminished by eradication infection. To evaluate there difference interleukin (IL)-6 levels H. pylori-positive -negative both before during FMF attacks; change IL-6 following successful treatment; MEFV gene mutations have an effect on levels. were evaluated 47 attacks....
Patients with sickle cell anemia have various forms of renal dysfunction.The purpose this study is to demonstrate the abnormalities HbSS patients' function in childhood. Renal studies were performed 55 patients homozygote and compared 13 healthy children. The blood timed urine samples obtained for hematological biochemical determinations.Mean serum creatinine, sodium, phosphorus calcium levels not statistically different between controls. Mean potassium uric acid significantly higher than...
Dyssynergic defecation, a subgroup of functional constipation, is relatively new definition, diagnostic criteria which have recently been described. Distribution subgroups constipation in our population scarcely known. We aimed to evaluate the demographic characteristics and defecation features patients as we determined frequency dyssynergic with community.Eighty-two patients, 52 women 30 men, were included study by using questionnaire after secondary causes excluded. Colonic transit time...