The present study involved in vivo evaluation of the growth promoting effects thymol and nanoemulsion their protection against Salmonella Typhimurium infection broilers. One-day old 2400 chicks were randomly divided into eight groups; negative positive control groups fed basal diet without additives (0.25, 0.5 1% each). At d 23, all except challenged with S. Typhimurium. Over total growing period, birds showed better performance even after challenge, which came parallel upregulation...

Salmonella enterica serovar Typhimurium (S. typhimurium) is known for its intracellular survival, evading the robust inflammation and adaptive immune response of host. The emergence decreased ciprofloxacin (CIP) susceptibility (DCS) requires a prolonged antibiotic course with increased dosage, leading to threatening, adverse effects. Moreover, antibiotic-resistant bacteria can persist in biofilms, causing serious diseases. Hence, we validated vitro vivo efficacy ciprofloxacin-loaded...

Abstract Promising therapy is needed for treating inflammatory bowel diseases (IBD) to overcome current treatment that inefficient and associated with unnecessary health risks. Recently, the concept of incorporating natural products into nanocarriers has been intended as a promising IBD via modulating their stability bioavailability. Thus, we aimed explore potential alleviating effects dietary nano-supplement combined bacillus strains ( Bacillus amyloliquefaciens ; BANPs) in colitis model....

Recently, the use of essential oils (EOs) or their bioactive compounds encapsulated by nanoparticles as alternative supplements for in-feed antimicrobials is gaining attention, especially in organic poultry production. Focusing on eugenol, its incorporation into nanoformulation a novel strategy to improve stability and bioavailability thus augment growth-boosting antimicrobial activities. Therefore, we explored eugenol nanoemulsion activities modulating growth, digestive gut barrier...

Salmonella enterica is an invasive intracellular pathogen and hires diverse systems to manipulate its survival in the host cells. could eavesdrop on cells, sensing responding produced adrenergic hormones other neurotransmitters, which results augmentation of virulence establishes accommodation The current study aims assess anti-virulence effect α-adrenergic antagonist terazosin S. Typhimurium. Our findings show that significantly reduced Typhimurium adhesion biofilm formation. Furthermore,...

Encapsulated phytochemicals with augmented therapeutic and nutritional characteristics have become promising alternatives to antimicrobials in the poultry industry. Hence, our key target was explore efficacy of liposomal encapsulation, as a novel carrier, for essential oils (LEOs) on growth, digestibility, intestinal microbiota, bacterial metabolites broiler chickens. Moreover, impact encapsulated EOs transcription mechanisms targeting genes encoding digestive enzymes, gut barrier functions...

Typical formulated broiler diets are deficient in n-3 poly-unsaturated fatty acids (PUFA) due to widening n-6:n-3 PUFA ratio which could greatly affect performance, immune system of birds and, more importantly, meat quality. This study was conducted evaluate the effect modifying dietary from plant and animal oil sources on behavior, cytokine mRNA expression, antioxidative status acid profile chickens. Birds (n = 420) were fed 7 enriched with different ratios as follows: sunflower control...

Foodborne pathogens have been associated with severe and complicated diseases. Therefore, these types of infections are a concern for public health officials food dairy industries. Regarding the wide-spread multidrug resistant (MDR) extensively drug (XDR) foodborne such as Salmonella Enteritidis (S. Enteritidis), new alternative therapeutic approaches urgently needed. we investigated antimicrobial, anti-virulence, immunostimulant activities stable formulation thymol nanoemulsion in an vivo...

This study compares between different selenium forms (sodium selenite; SeS, selenomethionine; Met-Se or nano-Se) and levels on growth performance, Se retention, antioxidative potential of fresh frozen meat, genes related to oxidative stress in Ross broilers. Birds (n = 450) were randomly divided into nine experimental groups with five replicates each fed diets supplemented 0.3, 0.45, 0.6 mg Se/kg as (SeS, Met-Se), nano-Se. For overall dietary inclusion nano-Se significantly increased (p <...

Phytogenic feed additives have been gaining considerable interest due to their ability improve gut health and thereby performance of broiler chickens. The impact Glycyrrhiza glabra (licorice) extract (GE) on expression genes coding for tight junction proteins protection Campylobacter jejuni colonization in broilers has not discussed until now. Thus, the current study assessed effective dose GE maximum growth chickens, clear-cut molecular mechanisms related integrity intestine, controlling C....

The aim of the present study was to evaluate mannan oligosaccharides (MOS) or glycerol (GLY) as a carbon source on biofloc systems Nile tilapia (O. niloticus) juveniles. Fish (n = 750) were reared in open flow (Controls) (B-GLY and B-MOS) fed with plant fish protein over period twelve weeks. Total ammonia nitrogen nitrate decreased groups, while volume increased B-MOS. Compared controls, B-MOS B-GLY exhibited higher weight gain improved feed conversion, irrespectively diet. Serum level...

Necrotic enteritis (NE) caused by Clostridium perfringens (C. perfringens) results in impaired bird growth performance and increased production costs. Nanotechnology application the poultry industry to control NE outbreaks is still not completely clarified. Therefore, efficacy of dietary garlic nano-hydrogel (G-NHG) on broilers performance, intestinal integrity, economic returns its potency alleviate C. levels using challenge model were addressed. A total 1200 male broiler chicks (Ross 308)...

Optimal combinations of essential oils (EOs) can enhance performance and maintain poultry productivity. The effects EOs with black pepper oil (BPO) or radish seed (RSO) on the expression digestive enzymes, lipogenesis, immunity, autophagy-related genes in broiler chickens were explored. Six dietary treatments for 300 one-day-old chicks allocated as follows: controls fed a basal diet, one group was an EO-supplemented diet (1.5 g/kg parsley, mint, carrot (1:1:1)), other groups received Eos +...

Oxidative stress is considered the main etiologic factor involved in inflammatory bowel disease (IBD). Integration of nanocarriers for natural therapeutic agents with antioxidant and anti-inflammatory potential a novel promising candidate curing IBD. Herein, colonic effects different concentrations quercetin nanoparticles (QT-NPs) were evaluated using dextran sulfate sodium (DSS)-induced colitis model. Following induction, efficacy mechanistic actions QT-NPs by assessing lesion severity,...

The oxidative stress facing fish during intensive production brings about diseases and mortalities that negatively influence their performance. Along with that, the increased awareness of omega-3 polyunsaturated fatty acids (omega-3-PUFAs) health benefits has been triggered introduction alternative additives in aqua feed cause not only modulation immune response but also fortification fillet. In this context, role microalgae mix (NSS) containing Nannochloropsis oculate Schizochytrium...

In the modern poultry industry, application of novel phytogenic bioactive compounds with antioxidant potential aims to enhance productivity and quality minimize stress associated diseases. Herein, myricetin, a natural flavonoid, was evaluated for first time on broiler chickens' performance, antioxidants immune modulating functions, tackling avian coccidiosis. A total 500 one-day-old chicks were divided into five groups. The negative (NC) infected control (IC) groups fed diet without...

Different sources of Zinc (Zn) were compared to assess their possible effects on performance, nutrients retention, mineral distribution and some serum parameters broiler chickens. A total 200 one-day old Ross 308 chicks divided into in equal four dietary treatments groups with five replicates each ten chicks. The experimental given the basal diet (inorganic ZnO), supplemented organic Zn (Zn methionine), nano-ZnO Znmix (organic nano-ZnO) at a concentration 50 mg/kg diet. After 42 days feeding...

Feeding broiler chickens on diets based cereal grains of high non-starch polysaccharides content such as wheat and barley can negatively impact their performance gut health. Plant extracts be used a potential tool to alleviate these negative effects. The present study assessed the effects dietary type inclusion plant extract blend (PEB) growth performance, intestinal histomorphology, caecal microflora, gene expression selected biomarkers for integrity in 42-d experiment. Ross-308 male...