Jiakun Zhang

ORCID: 0000-0003-3410-6009
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About
Contact & Profiles
Research Areas
  • Retinal Development and Disorders
  • Genomics and Chromatin Dynamics
  • Developmental Biology and Gene Regulation

St. Jude Children's Research Hospital
2022

Abstract Super-enhancers are expansive regions of genomic DNA comprised multiple putative enhancers that contribute to the dynamic gene expression patterns during development. This is particularly important in neurogenesis because many essential transcription factors have complex developmental stage– and cell–type specific across central nervous system. In developing retina, Vsx2 expressed retinal progenitor cells maintained differentiated bipolar neurons Müller glia. A single super-enhancer...

10.1038/s41467-021-27924-y article EN cc-by Nature Communications 2022-01-11
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