A5101895073- Sarcoma Diagnosis and Treatment
- Viral Infections and Outbreaks Research
- Cancer Cells and Metastasis
- Viral Infections and Vectors
- interferon and immune responses
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Reproductive System and Pregnancy
- Endometrial and Cervical Cancer Treatments
- Peptidase Inhibition and Analysis
- Gynecological conditions and treatments
- Bacteriophages and microbial interactions
- Congenital Diaphragmatic Hernia Studies
- Medical Imaging and Pathology Studies
- Medical and Biological Ozone Research
- Bone health and treatments
- NF-κB Signaling Pathways
- Protease and Inhibitor Mechanisms
- Renal Diseases and Glomerulopathies
- Tissue Engineering and Regenerative Medicine
- Nephrotoxicity and Medicinal Plants
- MicroRNA in disease regulation
- Respiratory viral infections research
- Bone Tumor Diagnosis and Treatments
Czech Academy of Sciences, Institute of Biotechnology
2023-2024
Academy of Military Medical Sciences
2023-2024
First Affiliated Hospital of Kunming Medical University
2024
Kunming Medical University
2024
First Affiliated Hospital of Anhui Medical University
2020
Anhui Medical University
2020
Central South University
2008-2015
Xiangya Hospital Central South University
2015
Zhejiang University
2010
Union Hospital
2008
Currently, bone marrow mesenchymal stem cells (BMSCs) have been reported to promote endometrial regeneration in rat models of mechanically injury-induced uterine adhesions (IUAs), but the therapeutic effects and mechanisms hypoxic BMSC-derived exosomes on IUAs not elucidated.
Transforming growth factor alpha (TGFA) gene is involved in the proliferation and metastasis of various tumors, but its role cell sensitivity to cisplatin chemotherapy unclear. In this study, we investigated mechanism underlying inhibitory effects on osteosarcoma cells. Osteosarcoma normal skeletal muscle tissues were collected from 26 patients by biopsy. TGFA was silenced or overexpressed Saos-2 cells transfection with TGFA-shRNA ORF clone, respectively. MiR-376c inhibited miR-376c sponge...
Viral inclusion bodies (IBs) are commonly formed during the replication of Ebola virus (EBOV) in infected cells, but their role viral immune evasion has rarely been explored. Here, we found that interferon regulatory factor 3 (IRF3), not TANK-binding kinase 1 (TBK-1) or IκB epsilon (IKKε), was recruited and sequestered IBs when cells were by EBOV transcription- replication-competent virus-like particles (trVLPs). NP/VP35-induced formation critical for IRF3 recruitment sequestration, probably...
Objective To construct a plasmid DNA encoding G glycoprotein of respiratory syncytial virus(RSV) and investigate the protective immune response against RSV infection. Methods Recombinant pcDNA3.1~G was constructed by standard RT-PCR based cloning procedure. The immunogenicity recombinant protein transiently expressed in HEK293 cells detected Western blot. BABL/c mice were intramuscularly immunized with pcDNA3.1~G. Samples lung, sera, bronchoalveolar lavage fluid(BALF) collected before after...
Objective To investigate the effect of zoledronic acid on vasculogenic mimicrv formatlon in osteosarcoma cell line LM8 vitro.Methods Osteosarcoma was tested fortheir ability to form mimicry and formation three-dimensional culture containing type I collagen.The ultrastructure cells determined by electron microscope laser scanning confocal microscope.Results Zoledronic significantly inhibited vitro,and decreased surface microvillus destroyed cytoskeletal protein F-actin cells.Conclusions The...