ABSTRACT Priestia megaterium strain AB-S79 isolated from active gold mine soil previously expressed in vitro heavy metal resistance and has a 5.7 Mb genome useful for biotechnological exploitation. This study used web-based bioinformatic resources to analyze P. genomic relatedness, decipher its secondary metabolite biosynthetic gene clusters (BGCs), better comprehend taxa. Genes were highly conserved across the 14 P . genomes examined here. The pangenome reflected total of 61,397...

Abstract The results of this study indicate that the maize rhizosphere remains a reservoir for microbial strains with unique beneficial properties. sought to provide an indigenous Bacillus strain bioprotective potential alleviate fusariosis in South Africa. We selected seven isolates (MORWBS1.1, MARBS2.7, VERBS5.5, MOREBS6.3, MOLBS8.5, MOLBS8.6, and NWUMFkBS10.5) biosuppressive effects against two fungal pathogens ( Fusarium graminearum culmorum ) based on 16S rDNA gene characterization...

In the interest of developing more effective and safer anti-tuberculosis drugs, we used a GCxGC-TOF-MS metabolomics research approach to investigate compare metabolic profiles Mtb in presence absence ciprofloxacin. The metabolites that best describe differences between compared groups were identified as markers characterizing changes induced by Malic acid was ranked most significantly altered metabolite marker ciprofloxacin, indicative an inhibition tricarboxylic (TCA) glyoxylate cycle Mtb....

Based on in vitro assessments, molecular and chemical analysis, Pseudomonas fulva PS9.1 Bacillus velezensis NWUMFkBS10.5 are candidate biocontrol agents for plant disease management including maize fusariosis, a caused by members of the Fusarium species. This vivo study evaluated bio-protective potential aforementioned rhizobacteria strains against proliferation pathogenic fungus graminearum (Fg). The results show that bacterized plants were not susceptible to Fg aggression antagonists...

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), still remains one of the leading causes death from a single infectious agent worldwide. The high prevalence this disease is mostly ascribed to rapid development drug resistance current anti-TB drugs, exacerbated lack patient adherence due toxicity. aforementioned highlights urgent need for new compounds with different antimycobacterial mechanisms action those currently being used. An N-alkyl quinolone; decoquinate derivative...

Abstract Phytopathogens causing mycotoxicoses in maize are a potential threat to grain quality and availability many producing countries including South Africa. The use of natural biological agents for controlling fusariosis other such plant diseases, as opposed the more traditional chemicals, is growing popularity globally, greater emphasis gets placed on public health. In this study, nine Fusarium inhibiting isolates representing subset 200 native Pseudomonas from rhizosphere 10 different...

We screened and isolated

Many strains from Bacillus thuringiensis are known for their genomic robustness and antimicrobial potentials. As a result, the quest biotechnological applications, especially in agroindustry (e.g., as biopesticides), has increased over years. This study documents genome sequencing probing of Fusarium antagonist (B. strain MORWBS1.1) with possible biopesticidal metabolite producing capacity South Africa. Based on vitro evaluation silico antiSMASH investigation, B. MORWBS1.1 exhibited...

In the interest of developing more effective and safer anti-Tuberculosis treatment, we aimed for a better understanding antimycobacterial action ciprofloxacin against Mycobacterium tuberculosis (Mtb). We used GCxGC-TOF-MS well described metabolomics statistical approaches, to investigate compare metabolic profiles Mtb in presence absence drug. The metabolites that best describe differences between compared groups were identified as markers characterizing changes induced by ciprofloxacin....

The genus Pseudomonas contains a variety of genomic robust strains and species, well known for their beneficial use in applications, hence the vast amount research done on this organism to date. We report here draft genome sequence an anti-Fusarium rhizospheric fulva HARBPS9.1 strain from South Africa. This analysis identified clusters genes responsible synthesis pyoverdin rhizomide HARBPS9.1; these compounds should confer competitive advantage pseudomonad.

ABSTRACT Genomic features of Staphylococcus auricularis PAPLE_T1 isolated from waste sample Carica papaya obtained Lagos State, Nigeria, revealed its putative capability to synthesize valuable secondary metabolites. S. has a 2.4 Mb genome and could be useful as biological agro-antibiotics, for soil bioremediation in biotechnological industry.

Candidate biocontrol agent Bacillus velezensis NWUMFkBS10.5 possesses unique genomic characteristics revealed by antiSMASH analysis and in vitro metabolomic elucidation. Besides its capability to produce antimicrobial lipopeptides, further silico genome profiling predicted the presence of metabolic pathways for synthesizing antioxidants like lampranthin-2, miraxanthin V, 2-decarboxybetanidin.

Lysinibacillus fusiformis PwPw_T2 isolated from deteriorating Ananas comosus sample collected Lagos State, Nigeria putatively possesses genomic features like potential enzymes catalyzing acetic acid production and xenobiotic compounds degradation via various pathways as indicated by its genome sequences. These could make the organism relevant in food waste valorization micro-biotechnology.

Pseudomonas iranensis ABS_30, isolated from gold mining soil, exhibits metal-resistant properties valuable for heavy metal removal. We report the draft genome sequencing of P. ABS_30 strain, which is 5.9 Mb in size.