- Edible Oils Quality and Analysis
- Cholesterol and Lipid Metabolism
- Advanced Glycation End Products research
- Antioxidant Activity and Oxidative Stress
- Blood disorders and treatments
- Genomics and Rare Diseases
- Neonatal Respiratory Health Research
- Neonatal and Maternal Infections
- Cystic Fibrosis Research Advances
Hospital Regional Universitario de Málaga
2019
The aim of this study was to assess the possible neuroprotective effect 3',4'-dihydroxyphenylglycol (DHPG), a polyphenol from extra virgin olive oil (EVOO), in an experimental model diabetes and whether is modified by presence another EVOO polyphenol, hydroxytyrosol (HT). assessed hypoxia-reoxygenation brain slices quantifying retinal nerve cells. animals were distributed as follows: (1) normoglycemic rats (NDR), (2) diabetic (DR), (3) DR treated with HT (5 mg/kg/day p.o.), (4) DHPG (0.5...
Hydroxytyrosol (HT) is the component primarily responsible for neuroprotective effect of extra virgin olive oil (EVOO). However, it less effective on its own than demonstrated EVOO, and this reason, can be postulated that there an interaction between several polyphenols EVOO. The objective study was to assess possible four EVOO (HT, tyrosol, dihydroxyphenylglycol, oleocanthal) in experimental model hypoxia-reoxygenation rat brain slices. lactate dehydrogenase (LDH) efflux, lipid...
Identifying newborns at risk for cystic fibrosis (CF) by newborn screening (NBS) using dried blood spot (DBS) specimens provides an opportunity presymptomatic detection. All NBS strategies CF begin with measuring immunoreactive trypsinogen (IRT). Pancreatitis-associated protein (PAP) has been suggested as second-tier testing. The main objective of this study was to evaluate the analytical performance IRT/PAP/IRT strategy versus current IRT/IRT over a two-year pilot including 68,502 newborns....