A5069376400- Autism Spectrum Disorder Research
- BRCA gene mutations in cancer
- Race, Genetics, and Society
- Genomics and Rare Diseases
- Genetics and Neurodevelopmental Disorders
- Genomic variations and chromosomal abnormalities
- History of Science and Medicine
- Prenatal Screening and Diagnostics
- Congenital heart defects research
- Genetics, Bioinformatics, and Biomedical Research
- Nutrition, Genetics, and Disease
- Child and Adolescent Health
- Coronary Artery Anomalies
- Fetal and Pediatric Neurological Disorders
- Congenital Heart Disease Studies
- Biotechnology and Related Fields
- Neuroethics, Human Enhancement, Biomedical Innovations
- Philosophy and History of Science
- Genetic Associations and Epidemiology
- Art History and Market Analysis
- Ethics and Legal Issues in Pediatric Healthcare
- Pregnancy and Medication Impact
- Bacillus and Francisella bacterial research
- Animal Genetics and Reproduction
- Historical Psychiatry and Medical Practices
University of California, San Diego
2016-2024
University of Bristol
2021
King Edward Memorial Hospital
2021
Harvard University
2014
Columbia University
2011-2012
This article builds on Hacking's framework of "dynamic nominalism" to show how knowledge about biological etiology can interact with the "kinds people" delineated by diagnostic categories in ways that "loop" or modify both over time. The authors use historical materials "geneticization" played a crucial role binding together autism as biosocial community and evidence from genetics research later made an important contribution expansion autism. In second part article, draw quantitative...
This paper reports and discusses ‘genomic designation’ as a way of classifying people. In genomic designation the object biomedical analysis — concomitant medical category that is subject to scientific, clinical, social action delineated on basis, while phenotype decentralized tabulated post factum. Unlike prominent sociological concepts such biosociality or geneticization, where genetic proclivities for explanations phenotypic categories affect processes, treats characteristics genome...
Abstract This paper presents a sociological examination of the role genetic counselors as advocates, not only for patients and their families, but also conditions themselves. In becoming activists new disorders, are helping to create categories that will shape expectations treatment regimens both existing those who yet be diagnosed. By virtue expertise position at intersection several key professions constituencies, likely play central in way testing technologies, especially ‘genotype‐first’...
In this article, we discuss the radical uncertainties unleashed by expanded prenatal genetics. We show how are now routinely screening fetuses in absence of two essential sorts information. At population level, do not have sound, unbiased data about prevalence, penetrance, and clinical variability most mutations. level proband, it is often too soon to discern relevant information fetus’ phenotype. First, outline longstanding ethical objections newborn for poorly understood genetic anomalies...
Human genetics has uncovered a vast trove of medically relevant changes in our genomes—variants and mutations that are both far more common difficult to interpret than experts anticipated. What will this mean as we move into an era genomic or "precision" medicine? For over century the overriding goal human was explain inheritance traits conditions hailed from disciplines like medicine, psychology, criminology. Yet today, genomics research is calling prevailing categories illness difference...
Scientific facts are an essential element of modern life. Yet, despite abundance illuminating work in science and technology studies (STS), we lack a rigorous sociological framework for explaining how scientific emerge, gain traction, then change over time. This article fills that gap. Drawing on Fleck ([1935] 1981), Haydu (1998), wealth STS scholarship, I develop comparative-historical approach called “reiterated fact-making” analyzes according to (1) the prevailing conditions possibility;...
Abstract This paper examines how the “narrative‐identities” of J ewish communities in I srael and US were unified through events surrounding srael's 1967 war with E gypt, ordan S yria. Using a range historical materials, show key elements two communities' identities rearranged untied new, shared narrative that linked H olocaust, victimhood srael. argue old Z ionist enabled new one, which turn helped bind discursively, materially politically. Finally, discuss implications for our...
The changing epidemiology of IBD suggests that environmental factors have a major role in inducing or modifying disease expression. Nevertheless, identifying modifiable is challenging. We aimed to determine the association very early-life exposure with subsequent development unique cohort follow-up nearly 50 years, by merging data from Jerusalem Perinatal Study (JPS) and Israeli Research Network (epiIIRN). linked two relevant datasets: epiIIRN JPS. former validated registry all patients 4...
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