- Advanced MRI Techniques and Applications
- Medical Imaging Techniques and Applications
- Cardiac Imaging and Diagnostics
- Atomic and Subatomic Physics Research
- NMR spectroscopy and applications
- Optical measurement and interference techniques
- Ultrasonics and Acoustic Wave Propagation
- Structural Health Monitoring Techniques
- Image Processing and 3D Reconstruction
- Cardiovascular Function and Risk Factors
- Advanced NMR Techniques and Applications
- Advanced Radiotherapy Techniques
- Distributed and Parallel Computing Systems
- Superconducting Materials and Applications
Columbia University
2022-2025
Cornell University
2024-2025
Weill Cornell Medicine
2025
Functional scans in cardiovascular magnetic resonance (CMR) adopting bSSFP sequences suffer from dark band artifacts due to B0 inhomogeneity. The best remedy mitigate this issue is through cardiac shimming. development of an optimal shim strategy for the human heart hindered by a limited understanding conditions clinical diagnostic orientations CMR. Here, we present high-resolution distributions imaging planes, derived simulations utilizing computed tomography (CT) images 1008 subjects, and...
Abstract Purpose High‐quality fat suppression is essential for various MRI applications. In musculoskeletal imaging, poor caused by severe B 0 inhomogeneity can obscure important lesions, potentially leading to inaccurate diagnoses. This problem particularly exacerbated in off‐isocenter where conventional shimming using second‐order spherical harmonic shim coils often proves inadequate due elevated inhomogeneity. To address this challenge, we configured a simple local insert provide...
Motivation: MRI has evolved into an indispensable tool, but remains inaccessible to much of the world’s population. Goal(s): To build a compact, low-cost, mid- high-field system capable producing diagnostic-quality images. Approach: A complete redesign MR scanner architecture and key technologies; including compact high temperature superconducting magnet, multi-coil gradient array, digital spectrometer. The required extensive testing prior integration initial imaging. Results:...
To design and implement a multi-coil (MC) array for B
Functional cardiac MRI scans employing balanced steady-state free precession sequences suffer from dark band artifacts in the myocardium due to B0 inhomogeneity. We recently introduced a novel method for theoretical derivation of distributions human heart. This study aims simulate heart across cycle using structural MR images and validate simulations via vivo measured phase-specific maps on same subjects at 3T.Cardiac field were acquired eight healthy 3T. conditions simulated based tissue...
Motivation: Balanced SSFP sequences in cardiovascular MRI suffer from dark band artifacts due to B0 inhomogeneity. Limited detail of vivo conditions apparent various population groups impede the development optimal cardiac shim methods. Goal(s): To validate our recently-published high-resolution simulation approach human heart based on structural CT images. Approach: Validation was achieved through direct comparison computationally derived images, vs. maps obtained experimentally same five...
Cardiac functional scans adopting bSSFP sequences suffer from dark band artifacts due to B0 inhomogeneity. The best remedy mitigate this issue is through cardiac shimming. A limited understanding of the conditions in clinical diagnostic orientations impedes development an optimal shim strategy human heart. Here we perform a theoretical analysis spherical harmonic at 3 T using static global approach and slice-specific dynamic updating short-axis views hearts 921 subjects as starting point for...
B0 inhomogeneity leads to imaging artifacts in cardiac magnetic resonance (MRI), particular dark band with steady-state free precession pulse sequences. The limited spatial resolution of MR-derived vivo maps and the lack population data prevent systematic analysis problem at hand development optimized shim strategies. We used readily available clinical computed tomography (CT) images simulate conditions human heart high resolution. Calculated fields showed consistency MRI-based measurements....
Motivation: Adequate B0 shimming of deep brain regions at 7T using 3rd order shims. Goal(s): Reproduce shim matrix calibration after hardware replacement and estimate possible compensation residual fields in vivo. Approach: Calibration the system was measured gradient coil. Results were compared with previous calibration. Whole-brain ROI-specific spherical harmonic decompositions maps performed optimized whole-brain shimming. Results: Shimming matrices could be reproduced high accuracy on...
As part of a multi-center effort to design and build an accessible 1.5 T head-only MRI scanner (NIH U01EB025153, PI M. Garwood), we designed constructed prototype multi-coil array fitting the limited available space capable generating linear non-linear image encoding fields as well strong concomitant localized B 0 shim fields. Here, describe construction process, present system characteristics experimental validation its field generation capabilities utilizing conventional 4 scanner.
This article highlights a research study on the fabrication of 25.2 T ultra-high field NMR magnet for an extreme condition user facility in China.
Cardiac MRI suffers susceptibility-induced artifacts due to B 0 inhomogeneity across the heart. The lack of population data in cardiac conditions and practical inability obtain such large populations impedes development optimal shim strategy. Here, we establish population-based from readily available CT images simulate maps 254 subjects with broad demographic parameters. results are expected develop subject- population-specific strategies.